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Biotransformation of a major beer prenylflavonoid - isoxanthohumol.
Z Naturforsch C 2018; 74(1-2):1-7ZN

Abstract

Microbial transformations of isoxanthohumol (1), a beer prenylated flavonoid, by 51 fungi were investigated. Many of the tested fungi cultures were capable of effective transformation of 1. Mucor hiemalis and Fusarium oxysporum converted isoxanthohumol (1) into isoxanthohumol 7-O-β-d-glucopyranoside (3) and (2R)-2″-(2″'-hydroxyisopropyl)-dihydrofurano[2″,3″:7,8]-4″,5-hydroxy-5-methoxyflavanone (4), respectively. No product was obtained in the transformation of 1 by Absidia glauca conducted in a phosphate buffer. In the same medium, Beauveria bassiana converted isoxanthohumol (1) to isoxanthohumol 7-O-β-d-4″'-O-methylglucopyranoside (2).

Authors+Show Affiliations

Department of Chemistry, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland.Department of Chemistry, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland.Department of Chemistry, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30864390

Citation

Bartmańska, Agnieszka, et al. "Biotransformation of a Major Beer Prenylflavonoid - Isoxanthohumol." Zeitschrift Fur Naturforschung. C, Journal of Biosciences, vol. 74, no. 1-2, 2018, pp. 1-7.
Bartmańska A, Tronina T, Popłoński J. Biotransformation of a major beer prenylflavonoid - isoxanthohumol. Z Naturforsch, C, J Biosci. 2018;74(1-2):1-7.
Bartmańska, A., Tronina, T., & Popłoński, J. (2018). Biotransformation of a major beer prenylflavonoid - isoxanthohumol. Zeitschrift Fur Naturforschung. C, Journal of Biosciences, 74(1-2), pp. 1-7. doi:10.1515/znc-2018-0101.
Bartmańska A, Tronina T, Popłoński J. Biotransformation of a Major Beer Prenylflavonoid - Isoxanthohumol. Z Naturforsch, C, J Biosci. 2018 Dec 19;74(1-2):1-7. PubMed PMID: 30864390.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Biotransformation of a major beer prenylflavonoid - isoxanthohumol. AU - Bartmańska,Agnieszka, AU - Tronina,Tomasz, AU - Popłoński,Jarosław, PY - 2018/07/02/received PY - 2018/10/08/accepted PY - 2019/3/14/entrez PY - 2019/3/14/pubmed PY - 2019/3/14/medline KW - Absidia glauca KW - Beauveria bassiana KW - Fusarium oxysporum KW - Mucor hiemalis KW - isoxanthohumol SP - 1 EP - 7 JF - Zeitschrift fur Naturforschung. C, Journal of biosciences JO - Z. Naturforsch., C, J. Biosci. VL - 74 IS - 1-2 N2 - Microbial transformations of isoxanthohumol (1), a beer prenylated flavonoid, by 51 fungi were investigated. Many of the tested fungi cultures were capable of effective transformation of 1. Mucor hiemalis and Fusarium oxysporum converted isoxanthohumol (1) into isoxanthohumol 7-O-β-d-glucopyranoside (3) and (2R)-2″-(2″'-hydroxyisopropyl)-dihydrofurano[2″,3″:7,8]-4″,5-hydroxy-5-methoxyflavanone (4), respectively. No product was obtained in the transformation of 1 by Absidia glauca conducted in a phosphate buffer. In the same medium, Beauveria bassiana converted isoxanthohumol (1) to isoxanthohumol 7-O-β-d-4″'-O-methylglucopyranoside (2). SN - 0939-5075 UR - https://www.unboundmedicine.com/medline/citation/30864390/Biotransformation_of_a_major_beer_prenylflavonoid_-_isoxanthohumol L2 - https://www.degruyter.com/doi/10.1515/znc-2018-0101 DB - PRIME DP - Unbound Medicine ER -