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Autologous transobturator sling as an alternative therapy for stress urinary incontinence.
Int J Gynaecol Obstet. 2019 Jun; 145(3):300-305.IJ

Abstract

OBJECTIVE

To evaluate efficacy and outcomes of the autologous transobturator midurethral sling for treatment of stress urinary incontinence (SUI).

METHODS

In a prospective cohort study, an autologous transobturator mid-urethral sling was used to treat SUI among women attending a university hospital in Montevideo, Uruguay, from June 2017 to July 2018. In the first phase, autologous tissue of the abdominis rectus fascia was collected. In the second phase, the midurethral sling was placed via the transobturator approach. Outcomes were measured every 3 months by the International Consultation on Incontinence Questionnaire Female Lower Urinary Tract Symptoms (ICIQ-FLUTS) Score. Preoperative and postoperative results were compared by Wilcoxon test.

RESULTS

Eighteen women with a median age of 51 years were enrolled. The median follow-up was 9 months (range 6-15 months). Overall, 17 women showed symptomatic improvement after the procedure. In a comparison of preoperative versus postoperative ICIQ-FLUTS questionnaires, improvement in the incontinence subscore was observed at 3 (P<0.001), 6 (P<0.001), and 12 (P=0.008) months. No severe complications were observed.

CONCLUSION

Use of an autologous transobturator urethral sling was found to be technically feasible and safe for SUI, with good short-term outcomes. Longer follow up and larger series are needed to validate the procedure.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Department of Obstetrics and Gynecology, School of Medicine, University of Uruguay, Montevideo, Uruguay.

Department of Obstetrics and Gynecology, School of Medicine, University of Uruguay, Montevideo, Uruguay.

Department of Obstetrics and Gynecology, School of Medicine, University of Uruguay, Montevideo, Uruguay.

Department of Obstetrics and Gynecology, School of Medicine, University of Uruguay, Montevideo, Uruguay.

Department of Obstetrics and Gynecology, School of Medicine, University of Uruguay, Montevideo, Uruguay.

Department of Urology, Mayo Clinic, Rochester, NY, USA.

MeSH

AdultAgedFemaleHumansMiddle AgedOutcome Assessment, Health CarePostoperative PeriodProspective StudiesSuburethral SlingsSurveys and QuestionnairesUrinary Incontinence, StressUrologic Surgical ProceduresUruguay

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30874306

Citation

Laufer, Joel, et al. "Autologous Transobturator Sling as an Alternative Therapy for Stress Urinary Incontinence." International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics, vol. 145, no. 3, 2019, pp. 300-305.

Laufer J, Scasso S, Bentancor V, et al. Autologous transobturator sling as an alternative therapy for stress urinary incontinence. Int J Gynaecol Obstet. 2019;145(3):300-305.

Laufer, J., Scasso, S., Bentancor, V., Bertoche, C., Sosa, C. G., & Elliott, D. S. (2019). Autologous transobturator sling as an alternative therapy for stress urinary incontinence. International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics, 145(3), 300-305. https://doi.org/10.1002/ijgo.12804

Laufer J, et al. Autologous Transobturator Sling as an Alternative Therapy for Stress Urinary Incontinence. Int J Gynaecol Obstet. 2019;145(3):300-305. PubMed PMID: 30874306.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Autologous transobturator sling as an alternative therapy for stress urinary incontinence. AU - Laufer,Joel, AU - Scasso,Santiago, AU - Bentancor,Valeria, AU - Bertoche,Cecilia, AU - Sosa,Claudio G, AU - Elliott,Daniel S, Y1 - 2019/04/01/ PY - 2018/09/06/received PY - 2018/11/16/revised PY - 2019/03/13/accepted PY - 2019/3/16/pubmed PY - 2019/6/19/medline PY - 2019/3/16/entrez KW - Autograft KW - Autologous sling KW - Stress incontinence KW - Transobturator KW - Urethral sling Urinary incontinence SP - 300 EP - 305 JF - International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics JO - Int J Gynaecol Obstet VL - 145 IS - 3 N2 - OBJECTIVE: To evaluate efficacy and outcomes of the autologous transobturator midurethral sling for treatment of stress urinary incontinence (SUI). METHODS: In a prospective cohort study, an autologous transobturator mid-urethral sling was used to treat SUI among women attending a university hospital in Montevideo, Uruguay, from June 2017 to July 2018. In the first phase, autologous tissue of the abdominis rectus fascia was collected. In the second phase, the midurethral sling was placed via the transobturator approach. Outcomes were measured every 3 months by the International Consultation on Incontinence Questionnaire Female Lower Urinary Tract Symptoms (ICIQ-FLUTS) Score. Preoperative and postoperative results were compared by Wilcoxon test. RESULTS: Eighteen women with a median age of 51 years were enrolled. The median follow-up was 9 months (range 6-15 months). Overall, 17 women showed symptomatic improvement after the procedure. In a comparison of preoperative versus postoperative ICIQ-FLUTS questionnaires, improvement in the incontinence subscore was observed at 3 (P<0.001), 6 (P<0.001), and 12 (P=0.008) months. No severe complications were observed. CONCLUSION: Use of an autologous transobturator urethral sling was found to be technically feasible and safe for SUI, with good short-term outcomes. Longer follow up and larger series are needed to validate the procedure. SN - 1879-3479 UR - https://www.unboundmedicine.com/medline/citation/30874306/Autologous_transobturator_sling_as_an_alternative_therapy_for_stress_urinary_incontinence_ DB - PRIME DP - Unbound Medicine ER -