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Screening of donor and candidate prior to solid organ transplantation-Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice.
Clin Transplant. 2019 09; 33(9):e13548.CT

Abstract

This updated section of the guideline from the Infectious Diseases Community of Practice of the American Society of Transplantation reviews the screening of donor and candidate prior to solid organ transplantation. Screening of donor and candidate is vital for optimizing post-transplant outcomes. Risk assessment based on detailed history and appropriate diagnostic evaluation is essential. Serologic screening for certain viral infections is important and aids in immunization counseling and risk mitigation of recipients. In addition to serology, nucleic acid testing for hepatitis B, hepatitis C and human immunodeficiency virus has been required for deceased and living donors. Certain endemic exposure may warrant additional evaluation beyond recommended standard testing. Diagnosed infection in the donor or recipient warrants treatment as well as additional testing and/or prophylaxis to mitigate risk for post-transplant complications. Certain infections in the immediate pre-transplant period may warrant delay of transplantation.

Authors+Show Affiliations

Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut.Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Boston, Massachusetts.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30900327

Citation

Malinis, Maricar, et al. "Screening of Donor and Candidate Prior to Solid Organ transplantation-Guidelines From the American Society of Transplantation Infectious Diseases Community of Practice." Clinical Transplantation, vol. 33, no. 9, 2019, pp. e13548.
Malinis M, Boucher HW, AST Infectious Diseases Community of Practice. Screening of donor and candidate prior to solid organ transplantation-Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice. Clin Transplant. 2019;33(9):e13548.
Malinis, M., & Boucher, H. W. (2019). Screening of donor and candidate prior to solid organ transplantation-Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice. Clinical Transplantation, 33(9), e13548. https://doi.org/10.1111/ctr.13548
Malinis M, Boucher HW, AST Infectious Diseases Community of Practice. Screening of Donor and Candidate Prior to Solid Organ transplantation-Guidelines From the American Society of Transplantation Infectious Diseases Community of Practice. Clin Transplant. 2019;33(9):e13548. PubMed PMID: 30900327.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Screening of donor and candidate prior to solid organ transplantation-Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice. AU - Malinis,Maricar, AU - Boucher,Helen W, AU - ,, Y1 - 2019/04/29/ PY - 2019/03/05/received PY - 2019/03/15/accepted PY - 2019/3/23/pubmed PY - 2020/10/2/medline PY - 2019/3/23/entrez KW - candidate evaluation KW - donor evaluation KW - donor-derived infections KW - infection SP - e13548 EP - e13548 JF - Clinical transplantation JO - Clin Transplant VL - 33 IS - 9 N2 - This updated section of the guideline from the Infectious Diseases Community of Practice of the American Society of Transplantation reviews the screening of donor and candidate prior to solid organ transplantation. Screening of donor and candidate is vital for optimizing post-transplant outcomes. Risk assessment based on detailed history and appropriate diagnostic evaluation is essential. Serologic screening for certain viral infections is important and aids in immunization counseling and risk mitigation of recipients. In addition to serology, nucleic acid testing for hepatitis B, hepatitis C and human immunodeficiency virus has been required for deceased and living donors. Certain endemic exposure may warrant additional evaluation beyond recommended standard testing. Diagnosed infection in the donor or recipient warrants treatment as well as additional testing and/or prophylaxis to mitigate risk for post-transplant complications. Certain infections in the immediate pre-transplant period may warrant delay of transplantation. SN - 1399-0012 UR - https://www.unboundmedicine.com/medline/citation/30900327/Screening_of_donor_and_candidate_prior_to_solid_organ_transplantation_Guidelines_from_the_American_Society_of_Transplantation_Infectious_Diseases_Community_of_Practice_ L2 - https://doi.org/10.1111/ctr.13548 DB - PRIME DP - Unbound Medicine ER -