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Paediatric inflammatory bowel disease: review with a focus on practice in low- to middle-income countries.
Paediatr Int Child Health 2019; 39(1):48-58PI

Abstract

Inflammatory bowel disease (IBD) should be considered in any child with a persistently altered bowel habit. Growth failure may be a consequence and there may also be extra-intestinal manifestations. Oesophago-gastroduodenoscopy and colonoscopy and conventional histopathology are the diagnostic tools of choice in IBD. The identification and management of children with IBD in resource-poor settings is difficult and there are few data on its prevalence in low- and middle-income countries. The main challenges are a lack of resources and infrastructure including trained personnel in settings where there are other priorities for maintaining the health and wellbeing of children. The identification and management of children with inflammatory bowel conditions often depends on the enthusiasm, skill and commitment of a few dedicated individuals. Abbreviations: ADA: Adalimumab; CD: Crohn disease; ECCO: European Crohn's and Colitis Organisation; EEN: exclusive enteral nutrition; ESPGHAN: European Society for Paediatric Gastroenterology Hepatology and Nutrition; FMT: faecal microbiota transplantation; GDP: gross domestic product; HIC: high-income countries; IBD: inflammatory bowel disease; IBDU: inflammatory bowel disease unclassified; IC: ileocolonoscopy; IFX: infliximab; IPAA: ileal pouch anal anastomosis; LMIC: low- and middle-income countries; MH: mucosal healing; OGD: oesophago-gastroduodenoscopy; PCDAI: Paediatric Crohn's Disease Activity Index; PIBD: paediatric inflammatory bowel disease; PUCAI: Paediatric Ulcerative Colitis Activity Index; UC: ulcerative colitis; UGIT: upper gastrointestinal tract; VEO-IBD: very early-onset IBD; WLE: white light endoscopy; 5-ASA: 5 aminosalicylic acid; 6-MP: 6-mercaptopurine.

Authors+Show Affiliations

a Alder Hey Children's NHS Foundation Trust , Liverpool , UK.b Bab Alhawa Relief Hospital , Syria.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

30900526

Citation

Dalzell, Anthony Mark, and Muhammad Eyad Ba'Ath. "Paediatric Inflammatory Bowel Disease: Review With a Focus On Practice in Low- to Middle-income Countries." Paediatrics and International Child Health, vol. 39, no. 1, 2019, pp. 48-58.
Dalzell AM, Ba'Ath ME. Paediatric inflammatory bowel disease: review with a focus on practice in low- to middle-income countries. Paediatr Int Child Health. 2019;39(1):48-58.
Dalzell, A. M., & Ba'Ath, M. E. (2019). Paediatric inflammatory bowel disease: review with a focus on practice in low- to middle-income countries. Paediatrics and International Child Health, 39(1), pp. 48-58. doi:10.1080/20469047.2019.1575056.
Dalzell AM, Ba'Ath ME. Paediatric Inflammatory Bowel Disease: Review With a Focus On Practice in Low- to Middle-income Countries. Paediatr Int Child Health. 2019;39(1):48-58. PubMed PMID: 30900526.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Paediatric inflammatory bowel disease: review with a focus on practice in low- to middle-income countries. AU - Dalzell,Anthony Mark, AU - Ba'Ath,Muhammad Eyad, PY - 2019/3/23/entrez PY - 2019/3/23/pubmed PY - 2019/5/7/medline KW - Crohn’s disease KW - Inflammatory bowel disease KW - low- to middle-income countries KW - medical management KW - paediatric KW - surgery KW - ulcerative colitis KW - very early onset SP - 48 EP - 58 JF - Paediatrics and international child health JO - Paediatr Int Child Health VL - 39 IS - 1 N2 - Inflammatory bowel disease (IBD) should be considered in any child with a persistently altered bowel habit. Growth failure may be a consequence and there may also be extra-intestinal manifestations. Oesophago-gastroduodenoscopy and colonoscopy and conventional histopathology are the diagnostic tools of choice in IBD. The identification and management of children with IBD in resource-poor settings is difficult and there are few data on its prevalence in low- and middle-income countries. The main challenges are a lack of resources and infrastructure including trained personnel in settings where there are other priorities for maintaining the health and wellbeing of children. The identification and management of children with inflammatory bowel conditions often depends on the enthusiasm, skill and commitment of a few dedicated individuals. Abbreviations: ADA: Adalimumab; CD: Crohn disease; ECCO: European Crohn's and Colitis Organisation; EEN: exclusive enteral nutrition; ESPGHAN: European Society for Paediatric Gastroenterology Hepatology and Nutrition; FMT: faecal microbiota transplantation; GDP: gross domestic product; HIC: high-income countries; IBD: inflammatory bowel disease; IBDU: inflammatory bowel disease unclassified; IC: ileocolonoscopy; IFX: infliximab; IPAA: ileal pouch anal anastomosis; LMIC: low- and middle-income countries; MH: mucosal healing; OGD: oesophago-gastroduodenoscopy; PCDAI: Paediatric Crohn's Disease Activity Index; PIBD: paediatric inflammatory bowel disease; PUCAI: Paediatric Ulcerative Colitis Activity Index; UC: ulcerative colitis; UGIT: upper gastrointestinal tract; VEO-IBD: very early-onset IBD; WLE: white light endoscopy; 5-ASA: 5 aminosalicylic acid; 6-MP: 6-mercaptopurine. SN - 2046-9055 UR - https://www.unboundmedicine.com/medline/citation/30900526/Paediatric_inflammatory_bowel_disease:_review_with_a_focus_on_practice_in_low-_to_middle-income_countries L2 - http://www.tandfonline.com/doi/full/10.1080/20469047.2019.1575056 DB - PRIME DP - Unbound Medicine ER -