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Vancomycin-resistant Enterococcus in solid organ transplant recipients: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice.
Clin Transplant. 2019 09; 33(9):e13549.CT

Abstract

These updated guidelines from the Infectious Diseases Community of Practice of the American Society of Transplantation address vancomycin-resistant enterococci (VRE) infections in SOT candidates and recipients. VRE are an important cause of infection and have been named by the CDC as a serious public threat. Typically, a commensal of the gastrointestinal tract, VRE may become pathogenic after abdominal organ manipulation like transplantation. This guideline reviews the microbiology, antimicrobial resistance mechanisms, epidemiology, and clinical manifestations of VRE infection in the context of solid organ transplantation. Treatment regimens including combination therapies and novel investigational agents are also reviewed. Finally, an updated appraisal of infection control measures relevant to VRE infection and colonization is presented.

Authors+Show Affiliations

Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30913322

Citation

Nellore, Anoma, et al. "Vancomycin-resistant Enterococcus in Solid Organ Transplant Recipients: Guidelines From the American Society of Transplantation Infectious Diseases Community of Practice." Clinical Transplantation, vol. 33, no. 9, 2019, pp. e13549.
Nellore A, Huprikar S, AST ID Community of Practice. Vancomycin-resistant Enterococcus in solid organ transplant recipients: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice. Clin Transplant. 2019;33(9):e13549.
Nellore, A., & Huprikar, S. (2019). Vancomycin-resistant Enterococcus in solid organ transplant recipients: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice. Clinical Transplantation, 33(9), e13549. https://doi.org/10.1111/ctr.13549
Nellore A, Huprikar S, AST ID Community of Practice. Vancomycin-resistant Enterococcus in Solid Organ Transplant Recipients: Guidelines From the American Society of Transplantation Infectious Diseases Community of Practice. Clin Transplant. 2019;33(9):e13549. PubMed PMID: 30913322.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vancomycin-resistant Enterococcus in solid organ transplant recipients: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice. AU - Nellore,Anoma, AU - Huprikar,Shirish, AU - ,, Y1 - 2019/05/07/ PY - 2019/03/18/received PY - 2019/03/19/accepted PY - 2019/3/27/pubmed PY - 2020/10/2/medline PY - 2019/3/27/entrez KW - antibiotic resistance KW - enterococcus KW - transplantation SP - e13549 EP - e13549 JF - Clinical transplantation JO - Clin Transplant VL - 33 IS - 9 N2 - These updated guidelines from the Infectious Diseases Community of Practice of the American Society of Transplantation address vancomycin-resistant enterococci (VRE) infections in SOT candidates and recipients. VRE are an important cause of infection and have been named by the CDC as a serious public threat. Typically, a commensal of the gastrointestinal tract, VRE may become pathogenic after abdominal organ manipulation like transplantation. This guideline reviews the microbiology, antimicrobial resistance mechanisms, epidemiology, and clinical manifestations of VRE infection in the context of solid organ transplantation. Treatment regimens including combination therapies and novel investigational agents are also reviewed. Finally, an updated appraisal of infection control measures relevant to VRE infection and colonization is presented. SN - 1399-0012 UR - https://www.unboundmedicine.com/medline/citation/30913322/Vancomycin_resistant_Enterococcus_in_solid_organ_transplant_recipients:_Guidelines_from_the_American_Society_of_Transplantation_Infectious_Diseases_Community_of_Practice_ L2 - https://doi.org/10.1111/ctr.13549 DB - PRIME DP - Unbound Medicine ER -