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Benefits of Vitamins in the Treatment of Parkinson's Disease.
Oxid Med Cell Longev 2019; 2019:9426867OM

Abstract

Parkinson's disease (PD) is the second most common neurodegenerative disease in the elderly, which is clinically characterized by bradykinesia, resting tremor, abnormal posture balance, and hypermyotonia. Currently, the pathogenic mechanism of PD remains unclear. Numerous clinical studies as well as animal and cell experiments have found a certain relationship between the vitamin family and PD. The antioxidant properties of vitamins and their biological functions of regulating gene expression may be beneficial for the treatment of PD. Current clinical evidence indicates that proper supplementation of various vitamins can reduce the incidence of PD in the general population and improve the clinical symptoms of patients with PD; nevertheless, the safety of regular vitamin supplements still needs to be highlighted. Vitamin supplementation may be an effective adjuvant treatment for PD. In this review, we summarized the biological correlations between vitamins and PD as well as the underlying pathophysiological mechanisms. Additionally, we elaborated the therapeutic potentials of vitamins for PD.

Authors+Show Affiliations

Department of Neurology and Neuroscience Center, First Hospital of Jilin University, Xinmin Street No. 71, Changchun 130000, China.Department of Pharmacology, College of Basic Medical Sciences, Jilin University, 126 Xin Min Street, Changchun, Jilin 130021, China.Department of Neurology and Neuroscience Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China.Department of Neurology and Neuroscience Center, First Hospital of Jilin University, Xinmin Street No. 71, Changchun 130000, China.Department of Neurology and Neuroscience Center, First Hospital of Jilin University, Xinmin Street No. 71, Changchun 130000, China.Department of Neurology and Neuroscience Center, First Hospital of Jilin University, Xinmin Street No. 71, Changchun 130000, China.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

30915197

Citation

Zhao, Xiuzhen, et al. "Benefits of Vitamins in the Treatment of Parkinson's Disease." Oxidative Medicine and Cellular Longevity, vol. 2019, 2019, p. 9426867.
Zhao X, Zhang M, Li C, et al. Benefits of Vitamins in the Treatment of Parkinson's Disease. Oxid Med Cell Longev. 2019;2019:9426867.
Zhao, X., Zhang, M., Li, C., Jiang, X., Su, Y., & Zhang, Y. (2019). Benefits of Vitamins in the Treatment of Parkinson's Disease. Oxidative Medicine and Cellular Longevity, 2019, p. 9426867. doi:10.1155/2019/9426867.
Zhao X, et al. Benefits of Vitamins in the Treatment of Parkinson's Disease. Oxid Med Cell Longev. 2019;2019:9426867. PubMed PMID: 30915197.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Benefits of Vitamins in the Treatment of Parkinson's Disease. AU - Zhao,Xiuzhen, AU - Zhang,Ming, AU - Li,Chunxiao, AU - Jiang,Xue, AU - Su,Yana, AU - Zhang,Ying, Y1 - 2019/02/20/ PY - 2018/10/04/received PY - 2019/02/04/accepted PY - 2019/3/28/entrez PY - 2019/3/28/pubmed PY - 2019/4/16/medline SP - 9426867 EP - 9426867 JF - Oxidative medicine and cellular longevity JO - Oxid Med Cell Longev VL - 2019 N2 - Parkinson's disease (PD) is the second most common neurodegenerative disease in the elderly, which is clinically characterized by bradykinesia, resting tremor, abnormal posture balance, and hypermyotonia. Currently, the pathogenic mechanism of PD remains unclear. Numerous clinical studies as well as animal and cell experiments have found a certain relationship between the vitamin family and PD. The antioxidant properties of vitamins and their biological functions of regulating gene expression may be beneficial for the treatment of PD. Current clinical evidence indicates that proper supplementation of various vitamins can reduce the incidence of PD in the general population and improve the clinical symptoms of patients with PD; nevertheless, the safety of regular vitamin supplements still needs to be highlighted. Vitamin supplementation may be an effective adjuvant treatment for PD. In this review, we summarized the biological correlations between vitamins and PD as well as the underlying pathophysiological mechanisms. Additionally, we elaborated the therapeutic potentials of vitamins for PD. SN - 1942-0994 UR - https://www.unboundmedicine.com/medline/citation/30915197/Benefits_of_Vitamins_in_the_Treatment_of_Parkinson's_Disease_ L2 - https://dx.doi.org/10.1155/2019/9426867 DB - PRIME DP - Unbound Medicine ER -