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Enterovirus D68-Associated Acute Respiratory Illness - New Vaccine Surveillance Network, United States, July-October, 2017 and 2018.
MMWR Morb Mortal Wkly Rep. 2019 Mar 29; 68(12):277-280.MM

Abstract

In the fall of 2014, an outbreak of enterovirus D68 (EV-D68)-associated acute respiratory illness (ARI) occurred in the United States (1,2); before 2014, EV-D68 was rarely reported to CDC (2,3). In the United States, reported EV-D68 detections typically peak during late summer and early fall (3). EV-D68 epidemiology is not fully understood because testing in clinical settings seldom has been available and detections are not notifiable to CDC. To better understand EV-D68 epidemiology, CDC recently established active, prospective EV-D68 surveillance among pediatric patients at seven U.S. medical centers through the New Vaccine Surveillance Network (NVSN) (4). This report details a preliminary characterization of EV-D68 testing and detections among emergency department (ED) and hospitalized patients with ARI at all NVSN sites during July 1-October 31, 2017, and the same period in 2018. Among patients with ARI who were tested, EV-D68 was detected in two patients (0.8%) in 2017 and 358 (13.9%) in 2018. Continued active, prospective surveillance of EV-D68-associated ARI is needed to better understand EV-D68 epidemiology in the United States.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

30921299

Citation

Kujawski, Stephanie A., et al. "Enterovirus D68-Associated Acute Respiratory Illness - New Vaccine Surveillance Network, United States, July-October, 2017 and 2018." MMWR. Morbidity and Mortality Weekly Report, vol. 68, no. 12, 2019, pp. 277-280.
Kujawski SA, Midgley CM, Rha B, et al. Enterovirus D68-Associated Acute Respiratory Illness - New Vaccine Surveillance Network, United States, July-October, 2017 and 2018. MMWR Morb Mortal Wkly Rep. 2019;68(12):277-280.
Kujawski, S. A., Midgley, C. M., Rha, B., Lively, J. Y., Nix, W. A., Curns, A. T., Payne, D. C., Englund, J. A., Boom, J. A., Williams, J. V., Weinberg, G. A., Staat, M. A., Selvarangan, R., Halasa, N. B., Klein, E. J., Sahni, L. C., Michaels, M. G., Shelley, L., McNeal, M., ... Gerber, S. I. (2019). Enterovirus D68-Associated Acute Respiratory Illness - New Vaccine Surveillance Network, United States, July-October, 2017 and 2018. MMWR. Morbidity and Mortality Weekly Report, 68(12), 277-280. https://doi.org/10.15585/mmwr.mm6812a1
Kujawski SA, et al. Enterovirus D68-Associated Acute Respiratory Illness - New Vaccine Surveillance Network, United States, July-October, 2017 and 2018. MMWR Morb Mortal Wkly Rep. 2019 Mar 29;68(12):277-280. PubMed PMID: 30921299.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Enterovirus D68-Associated Acute Respiratory Illness - New Vaccine Surveillance Network, United States, July-October, 2017 and 2018. AU - Kujawski,Stephanie A, AU - Midgley,Claire M, AU - Rha,Brian, AU - Lively,Joana Y, AU - Nix,W Allan, AU - Curns,Aaron T, AU - Payne,Daniel C, AU - Englund,Janet A, AU - Boom,Julie A, AU - Williams,John V, AU - Weinberg,Geoffrey A, AU - Staat,Mary A, AU - Selvarangan,Rangaraj, AU - Halasa,Natasha B, AU - Klein,Eileen J, AU - Sahni,Leila C, AU - Michaels,Marian G, AU - Shelley,Lynne, AU - McNeal,Monica, AU - Harrison,Christopher J, AU - Stewart,Laura S, AU - Lopez,Adriana S, AU - Routh,Janell A, AU - Patel,Manisha, AU - Oberste,M Steven, AU - Watson,John T, AU - Gerber,Susan I, Y1 - 2019/03/29/ PY - 2019/3/29/entrez PY - 2019/3/29/pubmed PY - 2019/3/30/medline SP - 277 EP - 280 JF - MMWR. Morbidity and mortality weekly report JO - MMWR Morb Mortal Wkly Rep VL - 68 IS - 12 N2 - In the fall of 2014, an outbreak of enterovirus D68 (EV-D68)-associated acute respiratory illness (ARI) occurred in the United States (1,2); before 2014, EV-D68 was rarely reported to CDC (2,3). In the United States, reported EV-D68 detections typically peak during late summer and early fall (3). EV-D68 epidemiology is not fully understood because testing in clinical settings seldom has been available and detections are not notifiable to CDC. To better understand EV-D68 epidemiology, CDC recently established active, prospective EV-D68 surveillance among pediatric patients at seven U.S. medical centers through the New Vaccine Surveillance Network (NVSN) (4). This report details a preliminary characterization of EV-D68 testing and detections among emergency department (ED) and hospitalized patients with ARI at all NVSN sites during July 1-October 31, 2017, and the same period in 2018. Among patients with ARI who were tested, EV-D68 was detected in two patients (0.8%) in 2017 and 358 (13.9%) in 2018. Continued active, prospective surveillance of EV-D68-associated ARI is needed to better understand EV-D68 epidemiology in the United States. SN - 1545-861X UR - https://www.unboundmedicine.com/medline/citation/30921299/Enterovirus_D68_Associated_Acute_Respiratory_Illness___New_Vaccine_Surveillance_Network_United_States_July_October_2017_and_2018_ L2 - https://doi.org/10.15585/mmwr.mm6812a1 DB - PRIME DP - Unbound Medicine ER -