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Gold and silver nanoparticles effects to the earthworm Eisenia fetida - the importance of tissue over soil concentrations.
Drug Chem Toxicol. 2021 Jan; 44(1):12-29.DC

Abstract

To address and to compare the respective impact of gold and silver nanoparticles (Au and Ag NPs) in soil invertebrate, the earthworm Eisenia fetida was exposed to soil containing 2, 10, and 50 mg/kg of Au and Ag in both nanoparticulate and ionic forms for 10 days. Both metal NPs were 2-15 times less bioavailable than their ionic forms, and displayed similar transfer coefficients from soil to earthworm tissues. Both metal NPs triggered the onset of an oxidative stress as illustrated by increased glutathione S-transferase levels, decreased catalase levels, and increased malondialdehyde concentrations. Protein carbonylation distinguished the nanoparticular from the ionic forms as its increase was observed only after exposure to the highest concentration of both metal NPs. Au and Ag NPs triggered DNA modifications even at the lowest concentration, and both repressed the expression of genes involved in the general defense and stress response at high concentrations as did their ionic counterparts. Despite the fact that both metal NPs were less bioavailable than their ionic forms, at equivalent concentrations accumulated within earthworms tissues they exerted equal or higher toxic potential than their ionic counterparts.Capsule: At equivalent concentrations accumulated within earthworm tissues Au and Ag NPs exert equal or higher toxic potential than their ionic forms.

Authors+Show Affiliations

CNRS, Laboratory of Fundamental Microbiology and Pathogenicity, European Institute of Chemistry and Biology, University of Bordeaux, Bordeaux, France.Department of Biology, Faculty of Science, Division of Zoology, University of Zagreb, Zagreb, Croatia.Department of Biology, Faculty of Science, Division of Zoology, University of Zagreb, Zagreb, Croatia.Department of Biology, Faculty of Science, Division of Botany, University of Zagreb, Zagreb, Croatia.Department for Marine and Environmental Research, Ruđer Bošković Institute, Zagreb, Croatia.Department of Biology, Faculty of Science, Division of Zoology, University of Zagreb, Zagreb, Croatia.PathCon Laboratories EU, Zagreb, Croatia.Department for Marine and Environmental Research, Ruđer Bošković Institute, Zagreb, Croatia.Department for Marine and Environmental Research, Ruđer Bošković Institute, Zagreb, Croatia.Department of Biology, Faculty of Science, Division of Zoology, University of Zagreb, Zagreb, Croatia.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30945571

Citation

Bourdineaud, Jean-Paul, et al. "Gold and Silver Nanoparticles Effects to the Earthworm Eisenia Fetida - the Importance of Tissue Over Soil Concentrations." Drug and Chemical Toxicology, vol. 44, no. 1, 2021, pp. 12-29.
Bourdineaud JP, Štambuk A, Šrut M, et al. Gold and silver nanoparticles effects to the earthworm Eisenia fetida - the importance of tissue over soil concentrations. Drug Chem Toxicol. 2021;44(1):12-29.
Bourdineaud, J. P., Štambuk, A., Šrut, M., Radić Brkanac, S., Ivanković, D., Lisjak, D., Sauerborn Klobučar, R., Dragun, Z., Bačić, N., & Klobučar, G. I. V. (2021). Gold and silver nanoparticles effects to the earthworm Eisenia fetida - the importance of tissue over soil concentrations. Drug and Chemical Toxicology, 44(1), 12-29. https://doi.org/10.1080/01480545.2019.1567757
Bourdineaud JP, et al. Gold and Silver Nanoparticles Effects to the Earthworm Eisenia Fetida - the Importance of Tissue Over Soil Concentrations. Drug Chem Toxicol. 2021;44(1):12-29. PubMed PMID: 30945571.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gold and silver nanoparticles effects to the earthworm Eisenia fetida - the importance of tissue over soil concentrations. AU - Bourdineaud,Jean-Paul, AU - Štambuk,Anamaria, AU - Šrut,Maja, AU - Radić Brkanac,Sandra, AU - Ivanković,Dušica, AU - Lisjak,Damir, AU - Sauerborn Klobučar,Roberta, AU - Dragun,Zrinka, AU - Bačić,Niko, AU - Klobučar,Göran I V, Y1 - 2019/04/04/ PY - 2019/4/5/pubmed PY - 2021/8/4/medline PY - 2019/4/5/entrez KW - DNA damage KW - Metallothioneins KW - catalase KW - gene expression KW - glutathione reductase KW - gold KW - nanoparticles KW - silver SP - 12 EP - 29 JF - Drug and chemical toxicology JO - Drug Chem Toxicol VL - 44 IS - 1 N2 - To address and to compare the respective impact of gold and silver nanoparticles (Au and Ag NPs) in soil invertebrate, the earthworm Eisenia fetida was exposed to soil containing 2, 10, and 50 mg/kg of Au and Ag in both nanoparticulate and ionic forms for 10 days. Both metal NPs were 2-15 times less bioavailable than their ionic forms, and displayed similar transfer coefficients from soil to earthworm tissues. Both metal NPs triggered the onset of an oxidative stress as illustrated by increased glutathione S-transferase levels, decreased catalase levels, and increased malondialdehyde concentrations. Protein carbonylation distinguished the nanoparticular from the ionic forms as its increase was observed only after exposure to the highest concentration of both metal NPs. Au and Ag NPs triggered DNA modifications even at the lowest concentration, and both repressed the expression of genes involved in the general defense and stress response at high concentrations as did their ionic counterparts. Despite the fact that both metal NPs were less bioavailable than their ionic forms, at equivalent concentrations accumulated within earthworms tissues they exerted equal or higher toxic potential than their ionic counterparts.Capsule: At equivalent concentrations accumulated within earthworm tissues Au and Ag NPs exert equal or higher toxic potential than their ionic forms. SN - 1525-6014 UR - https://www.unboundmedicine.com/medline/citation/30945571/Gold_and_silver_nanoparticles_effects_to_the_earthworm_Eisenia_fetida___the_importance_of_tissue_over_soil_concentrations_ L2 - https://www.tandfonline.com/doi/full/10.1080/01480545.2019.1567757 DB - PRIME DP - Unbound Medicine ER -