Tags

Type your tag names separated by a space and hit enter

Leonardo da Vinci's studies of the brain.
Lancet. 2019 Apr 06; 393(10179):1465-1472.Lct

Abstract

Leonardo da Vinci (1452-1519) contributed to the study of the nervous system. His earliest surviving anatomical drawings (circa 1485-93) included studies of the skull, brain, and cerebral ventricles. These works reflected his efforts to understand medieval psychology, including the localisation of sensory and motor functions to the brain. He was also the first to pith a frog, concluding that piercing the spinal medulla causes immediate death. After a 10-year interval in the early 1500s Leonardo resumed his anatomical studies and developed a method to inject hot wax into the ventricular system, creating a cast that showed the shape and extent of the ventricles. During this period he also progressed in his understanding of the anatomy of the cranial nerves. Besides being the first to identify the olfactory nerve as a cranial nerve, his dissections showed him that contrary to previous theories, the nerves do not converge on the lateral or third ventricles. Leonardo also performed detailed studies of the peripheral nervous system. Although his discoveries had little influence on the development of the field of anatomy, they represent an astonishingly sharp break from the field that had seen little if any progress in the previous 13 centuries. His work reflects the emergence of the modern scientific era and forms a key part of his integrative approach to art and science.

Authors+Show Affiliations

Department of Neurology, Kennedy Krieger Institute, Baltimore, MD, USA. Electronic address: pevsner@kennedykrieger.org.

Pub Type(s)

Biography
Historical Article
Journal Article
Review

Language

eng

PubMed ID

30967217

Citation

Pevsner, Jonathan. "Leonardo Da Vinci's Studies of the Brain." Lancet (London, England), vol. 393, no. 10179, 2019, pp. 1465-1472.
Pevsner J. Leonardo da Vinci's studies of the brain. Lancet. 2019;393(10179):1465-1472.
Pevsner, J. (2019). Leonardo da Vinci's studies of the brain. Lancet (London, England), 393(10179), 1465-1472. https://doi.org/10.1016/S0140-6736(19)30302-2
Pevsner J. Leonardo Da Vinci's Studies of the Brain. Lancet. 2019 Apr 6;393(10179):1465-1472. PubMed PMID: 30967217.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Leonardo da Vinci's studies of the brain. A1 - Pevsner,Jonathan, Y1 - 2019/04/04/ PY - 2018/11/11/received PY - 2019/01/24/revised PY - 2019/01/25/accepted PY - 2019/4/11/entrez PY - 2019/4/11/pubmed PY - 2019/5/9/medline SP - 1465 EP - 1472 JF - Lancet (London, England) JO - Lancet VL - 393 IS - 10179 N2 - Leonardo da Vinci (1452-1519) contributed to the study of the nervous system. His earliest surviving anatomical drawings (circa 1485-93) included studies of the skull, brain, and cerebral ventricles. These works reflected his efforts to understand medieval psychology, including the localisation of sensory and motor functions to the brain. He was also the first to pith a frog, concluding that piercing the spinal medulla causes immediate death. After a 10-year interval in the early 1500s Leonardo resumed his anatomical studies and developed a method to inject hot wax into the ventricular system, creating a cast that showed the shape and extent of the ventricles. During this period he also progressed in his understanding of the anatomy of the cranial nerves. Besides being the first to identify the olfactory nerve as a cranial nerve, his dissections showed him that contrary to previous theories, the nerves do not converge on the lateral or third ventricles. Leonardo also performed detailed studies of the peripheral nervous system. Although his discoveries had little influence on the development of the field of anatomy, they represent an astonishingly sharp break from the field that had seen little if any progress in the previous 13 centuries. His work reflects the emergence of the modern scientific era and forms a key part of his integrative approach to art and science. SN - 1474-547X UR - https://www.unboundmedicine.com/medline/citation/30967217/Leonardo_da_Vinci's_studies_of_the_brain_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0140-6736(19)30302-2 DB - PRIME DP - Unbound Medicine ER -