Tags

Type your tag names separated by a space and hit enter

[Famous veteran traditional Chinese medicine doctors' medication rules in treating spermatorrhea].
Zhongguo Zhong Yao Za Zhi. 2019 Mar; 44(6):1266-1272.ZZ

Abstract

To explore famous veteran traditional Chinese medicine(TCM) doctors' medication rules in treating spermatorrhea based on the medical cases about spermatorrhea collected from Hundred TCM Clinical Doctors of Hundred Years in China and Proven Cases and National Medical Master Test Case. Researchers extracted such data as medicinal and therapies from these cases according to the inclusion and exclusion criteria. Then,Excle 2010,SPSS Clementine 12. 0 and SPSS 22. 0 were adopted respectively for frequency analysis,association rules analysis,cluster analysis and factor analysis. Cluster analysis was carried out by Ochiai algorithm of binary variable data,one of the systematic clustering methods. And principal component analysis was used for factor analysis. Finally,27 medical cases and 41 prescriptions were included in total. The frequency analysis showed that the most common therapy was the astringent therapy(n = 28),which was followed by the tonifying method,tranquilizing method,heat-clearing method,damp-dispelling method and Qiregulating method. The top three kinds of high-frequency traditional Chinese medicines were Poria,Ostreae Concha and Dioscoreae Rhizoma. The association rules analysis found out 11 association rules of medicine pairs,23 association rules of medicine combinations of the three kinds of herbs and 6 association rules of medicine combinations of five kinds of herbs. Among them,the representatives were Rubi Fructus→Fossilia Ossis Mastodi,Rehmanniae Radix Praeparata + Corni Fructus→Dioscoreae Rhizoma,and Pinelliae Rhizoma→Citri Reticulatae Pericarpium,which showed the therapeutic characteristics of astringing,tonifying the kidney and replenishing essence,fortifying the spleen and dispelling dampness. Moreover,7 medicine groups with relevance were extracted from the tree map generated by cluster analysis,including " Phellodendri Chinensis Cortex and Anemarrhenae Rhizoma" and " Angelicae Sinensis Radix,Rehmanniae Radix,Bupleuri Radix and Glycyrrhizae Radix et Rhizoma",which demonstrated the effects of nourishing Yin and purging fire,tonifying and soothing the liver. Besides,totally 12 common factors were obtained according to factor analysis,including 14 drug combinations,like " Amomi Fructus,Anemarrhenae Rhizoma and Phellodendri Chinensis Cortex" and " Nelumbinis Stamen,Moutan Cortex,Poria and Scrophulariae Radix",which indicated the compatibility characteristics of tonifying the spleen and purging fire,dispelling dampness and clearing heat. In conclusion,data mining techniques(including frequency analysis,association rules analysis,cluster analysis and factor analysis) were used to comprehensively analyze the famous veteran TCM doctors' medication rules in treating spermatorrhea,which was helpful for guiding the clinical practice of treating spermatorrhea in TCM.

Authors+Show Affiliations

the First Clinical Medical College,Guangzhou University of Chinese Medicine Guangzhou 510405,China.the First Clinical Medical College,Guangzhou University of Chinese Medicine Guangzhou 510405,China.the First Clinical Medical College,Guangzhou University of Chinese Medicine Guangzhou 510405,China.the First Clinical Medical College,Guangzhou University of Chinese Medicine Guangzhou 510405,China.the First Clinical Medical College,Guangzhou University of Chinese Medicine Guangzhou 510405,China.the First Clinical Medical College,Guangzhou University of Chinese Medicine Guangzhou 510405,China.the First Clinical Medical College,Guangzhou University of Chinese Medicine Guangzhou 510405,China.the First Clinical Medical College,Guangzhou University of Chinese Medicine Guangzhou 510405,China.the First Clinical Medical College,Guangzhou University of Chinese Medicine Guangzhou 510405,China.School of Basic Medical Science,Guangzhou University of Chinese Medicine Guangzhou 510405,China.

Pub Type(s)

Journal Article

Language

chi

PubMed ID

30989993

Citation

Qi, Xiang-Jun, et al. "[Famous Veteran Traditional Chinese Medicine Doctors' Medication Rules in Treating Spermatorrhea]." Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, vol. 44, no. 6, 2019, pp. 1266-1272.
Qi XJ, Chen TY, Zhang ZP, et al. [Famous veteran traditional Chinese medicine doctors' medication rules in treating spermatorrhea]. Zhongguo Zhong Yao Za Zhi. 2019;44(6):1266-1272.
Qi, X. J., Chen, T. Y., Zhang, Z. P., Fang, C. S., Chen, G. M., Chen, X. Y., Lu, Y. Q., Chen, Y. M., Liang, H. R., & Lang, J. Y. (2019). [Famous veteran traditional Chinese medicine doctors' medication rules in treating spermatorrhea]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 44(6), 1266-1272. https://doi.org/10.19540/j.cnki.cjcmm.20181128.002
Qi XJ, et al. [Famous Veteran Traditional Chinese Medicine Doctors' Medication Rules in Treating Spermatorrhea]. Zhongguo Zhong Yao Za Zhi. 2019;44(6):1266-1272. PubMed PMID: 30989993.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Famous veteran traditional Chinese medicine doctors' medication rules in treating spermatorrhea]. AU - Qi,Xiang-Jun, AU - Chen,Teng-Yu, AU - Zhang,Zhao-Ping, AU - Fang,Cai-Shan, AU - Chen,Guo-Ming, AU - Chen,Xue-Yan, AU - Lu,Yi-Qian, AU - Chen,Yue-Mei, AU - Liang,Hao-Rui, AU - Lang,Jian-Ying, PY - 2019/4/17/entrez PY - 2019/4/17/pubmed PY - 2019/8/16/medline KW - data mining KW - famous veteran traditional Chinese medicine doctor KW - medication rules KW - spermatorrhea SP - 1266 EP - 1272 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 44 IS - 6 N2 - To explore famous veteran traditional Chinese medicine(TCM) doctors' medication rules in treating spermatorrhea based on the medical cases about spermatorrhea collected from Hundred TCM Clinical Doctors of Hundred Years in China and Proven Cases and National Medical Master Test Case. Researchers extracted such data as medicinal and therapies from these cases according to the inclusion and exclusion criteria. Then,Excle 2010,SPSS Clementine 12. 0 and SPSS 22. 0 were adopted respectively for frequency analysis,association rules analysis,cluster analysis and factor analysis. Cluster analysis was carried out by Ochiai algorithm of binary variable data,one of the systematic clustering methods. And principal component analysis was used for factor analysis. Finally,27 medical cases and 41 prescriptions were included in total. The frequency analysis showed that the most common therapy was the astringent therapy(n = 28),which was followed by the tonifying method,tranquilizing method,heat-clearing method,damp-dispelling method and Qiregulating method. The top three kinds of high-frequency traditional Chinese medicines were Poria,Ostreae Concha and Dioscoreae Rhizoma. The association rules analysis found out 11 association rules of medicine pairs,23 association rules of medicine combinations of the three kinds of herbs and 6 association rules of medicine combinations of five kinds of herbs. Among them,the representatives were Rubi Fructus→Fossilia Ossis Mastodi,Rehmanniae Radix Praeparata + Corni Fructus→Dioscoreae Rhizoma,and Pinelliae Rhizoma→Citri Reticulatae Pericarpium,which showed the therapeutic characteristics of astringing,tonifying the kidney and replenishing essence,fortifying the spleen and dispelling dampness. Moreover,7 medicine groups with relevance were extracted from the tree map generated by cluster analysis,including " Phellodendri Chinensis Cortex and Anemarrhenae Rhizoma" and " Angelicae Sinensis Radix,Rehmanniae Radix,Bupleuri Radix and Glycyrrhizae Radix et Rhizoma",which demonstrated the effects of nourishing Yin and purging fire,tonifying and soothing the liver. Besides,totally 12 common factors were obtained according to factor analysis,including 14 drug combinations,like " Amomi Fructus,Anemarrhenae Rhizoma and Phellodendri Chinensis Cortex" and " Nelumbinis Stamen,Moutan Cortex,Poria and Scrophulariae Radix",which indicated the compatibility characteristics of tonifying the spleen and purging fire,dispelling dampness and clearing heat. In conclusion,data mining techniques(including frequency analysis,association rules analysis,cluster analysis and factor analysis) were used to comprehensively analyze the famous veteran TCM doctors' medication rules in treating spermatorrhea,which was helpful for guiding the clinical practice of treating spermatorrhea in TCM. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/30989993/[Famous_veteran_traditional_Chinese_medicine_doctors'_medication_rules_in_treating_spermatorrhea]_ DB - PRIME DP - Unbound Medicine ER -