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An Extended Endoscopic Endonasal Approach for Sellar Area Chondrosarcoma: A Case Report and Literature Review.
World Neurosurg. 2019 Jul; 127:469-477.WN

Abstract

BACKGROUND

Chondrosarcoma is a malignant tumor that originates from mesenchymal cells that have differentiated into chondrocytes, often growing laterally, rarely seen in the cranium, and seldom seen in the saddle area. We believe that only a few cases have been reported in the literature. We report a case of pituitary fossa chondrosarcoma, which was completely resected by an extended endoscopic endonasal approach, and a literature review.

CASE DESCRIPTION

A 20-year-old man was admitted to hospital with bilateral temporal headache and blurred vision, without any history of sexual dysfunction or diabetes insipidus. Endocrine function was normal. Computed tomography of the head showed calcified sellar lesions and sellar bone destruction, which were closely associated with the right cavernous sinus. Magnetic resonance imaging showed saddle area space-occupying lesions, with low signal on the T1-weighted image and high signal on the T2-weighted image, uneven enhancement by enhanced scanning, and unclear pituitary display. The tumor was completely resected by an extended endoscopic endonasal approach and confirmed by magnetic resonance imaging. Postoperative pathology revealed conventional chondrosarcoma (World Health Organization grade II). Postsurgical visual acuity also improved. The patient did not receive radiotherapy or chemotherapy. No recurrence was found at 10-month follow-up.

CONCLUSIONS

Sellar region chondrosarcoma is rare. For space-occupying lesions in this area, chondrosarcoma should be considered and not necessarily pituitary adenoma, craniopharyngioma, meningioma, and chordoma. The extended endoscopic endonasal approach represents a good treatment option for sellar area chondrosarcoma.

Authors+Show Affiliations

Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China.Department of Neurosurgery, First Hospital of Nanping City, Nanping, Fujian, People's Republic of China.Department of Neurosurgery, First Hospital of Nanping City, Nanping, Fujian, People's Republic of China.Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China. Electronic address: 893416880@qq.com.Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China.Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China.Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China.Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China.Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China.Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China.

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

30995554

Citation

Zhang, Yuanlong, et al. "An Extended Endoscopic Endonasal Approach for Sellar Area Chondrosarcoma: a Case Report and Literature Review." World Neurosurgery, vol. 127, 2019, pp. 469-477.
Zhang Y, Huang J, Zhang C, et al. An Extended Endoscopic Endonasal Approach for Sellar Area Chondrosarcoma: A Case Report and Literature Review. World Neurosurg. 2019;127:469-477.
Zhang, Y., Huang, J., Zhang, C., Jiang, C., Ding, C., Lin, Y., Wu, X., Wang, C., Kang, D., & Lin, Z. (2019). An Extended Endoscopic Endonasal Approach for Sellar Area Chondrosarcoma: A Case Report and Literature Review. World Neurosurgery, 127, 469-477. https://doi.org/10.1016/j.wneu.2019.04.075
Zhang Y, et al. An Extended Endoscopic Endonasal Approach for Sellar Area Chondrosarcoma: a Case Report and Literature Review. World Neurosurg. 2019;127:469-477. PubMed PMID: 30995554.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An Extended Endoscopic Endonasal Approach for Sellar Area Chondrosarcoma: A Case Report and Literature Review. AU - Zhang,Yuanlong, AU - Huang,Jinsheng, AU - Zhang,Chunlin, AU - Jiang,Changzhen, AU - Ding,Chenyu, AU - Lin,Yuanxiang, AU - Wu,Xiyue, AU - Wang,Chenyang, AU - Kang,Dezhi, AU - Lin,Zhangya, Y1 - 2019/04/14/ PY - 2019/01/29/received PY - 2019/04/06/revised PY - 2019/04/08/accepted PY - 2019/4/18/pubmed PY - 2020/1/21/medline PY - 2019/4/18/entrez KW - Chondrosarcoma KW - Neuroendoscopy KW - Sellar area SP - 469 EP - 477 JF - World neurosurgery JO - World Neurosurg VL - 127 N2 - BACKGROUND: Chondrosarcoma is a malignant tumor that originates from mesenchymal cells that have differentiated into chondrocytes, often growing laterally, rarely seen in the cranium, and seldom seen in the saddle area. We believe that only a few cases have been reported in the literature. We report a case of pituitary fossa chondrosarcoma, which was completely resected by an extended endoscopic endonasal approach, and a literature review. CASE DESCRIPTION: A 20-year-old man was admitted to hospital with bilateral temporal headache and blurred vision, without any history of sexual dysfunction or diabetes insipidus. Endocrine function was normal. Computed tomography of the head showed calcified sellar lesions and sellar bone destruction, which were closely associated with the right cavernous sinus. Magnetic resonance imaging showed saddle area space-occupying lesions, with low signal on the T1-weighted image and high signal on the T2-weighted image, uneven enhancement by enhanced scanning, and unclear pituitary display. The tumor was completely resected by an extended endoscopic endonasal approach and confirmed by magnetic resonance imaging. Postoperative pathology revealed conventional chondrosarcoma (World Health Organization grade II). Postsurgical visual acuity also improved. The patient did not receive radiotherapy or chemotherapy. No recurrence was found at 10-month follow-up. CONCLUSIONS: Sellar region chondrosarcoma is rare. For space-occupying lesions in this area, chondrosarcoma should be considered and not necessarily pituitary adenoma, craniopharyngioma, meningioma, and chordoma. The extended endoscopic endonasal approach represents a good treatment option for sellar area chondrosarcoma. SN - 1878-8769 UR - https://www.unboundmedicine.com/medline/citation/30995554/An_Extended_Endoscopic_Endonasal_Approach_for_Sellar_Area_Chondrosarcoma:_A_Case_Report_and_Literature_Review_ DB - PRIME DP - Unbound Medicine ER -