Tags

Type your tag names separated by a space and hit enter

The cation competition and electrostatic theory are equally valid in quantifying the toxicity of trivalent rare earth ions (Y3+ and Ce3+) to Triticum aestivum.
Environ Pollut. 2019 Jul; 250:456-463.EP

Abstract

There is a lack of appropriate models to delineate the toxicity of rare earth elements (REEs) while taking into account the factors that affect bioavailability. Here, standardized wheat (Triticum aestivum L.) root elongation tests were conducted to examine the impact of exposure conditions (i.e., varying Ca, Mg, Na, K and pH levels) on Y and Ce toxicity. Cation competition and electrostatic theory were examined for their applicability in explaining the observed variations in toxicity. Only Ca2+ and Mg2+ significantly alleviated the toxicity of Y3+ and Ce3+, while Na+, K+ and H+ showed no significant effects. Based on the cation competition, the derived binding constants for the hypothetical biotic ligands of wheat logKCaBL, logKMgBL, logKYBL, and logKCeBL were 3.87, 3.59, 6.70, and 6.48, respectively. The biotic ligand model (BLM) succeeded in predicting toxicities of Y and Ce, with more than 93% of the variance in toxicity explained. Given the BLM requires large data sets for deriving model parameters, attempts were further made to explore a simpler electrostatic based model to quantify REEs toxicity. The results demonstrated that the predictive capacity of the electrostatic approach, which considers ion activities at the plasma membrane surface, was comparable to that of BLM with at least 87% of the variations in toxicity explained. This suggested that the electrostatic theory can serve as a surrogate to BLM in modeling Y and Ce toxicities. Therefore, we recommend the BLM and electrostatic-based model as effective approaches to incorporate bioavailability in quantifying REEs toxicity in the presence of various levels of other major cations.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Gong B
School of Environmental Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
He E
School of Environmental Science and Engineering, Sun Yat-sen University, Guangzhou, 510275, China.
Qiu H
School of Environmental Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China; Shanghai Institute of Pollution Control and Ecological Security, Shanghai, 200092, China. Electronic address: haoqiu@sjtu.edu.cn.
Li J
School of Environmental Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Ji J
School of Environmental Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Peijnenburg WJGM
Institute of Environmental Sciences, Leiden University, Leiden, 2333CC, the Netherlands; National Institute of Public Health and the Environment, Center for the Safety of Substances and Products, Bilthoven 3720 BA, the Netherlands.
Liu Y
Faculty of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming, 650500, China.
Zhao L
School of Environmental Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Cao X
School of Environmental Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China; Shanghai Institute of Pollution Control and Ecological Security, Shanghai, 200092, China.

MeSH

Biological AvailabilityCationsLigandsMetals, Rare EarthModels, BiologicalSodiumSoil PollutantsStatic ElectricityTriticum

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31026692

Citation

Gong, Bing, et al. "The Cation Competition and Electrostatic Theory Are Equally Valid in Quantifying the Toxicity of Trivalent Rare Earth Ions (Y3+ and Ce3+) to Triticum Aestivum." Environmental Pollution (Barking, Essex : 1987), vol. 250, 2019, pp. 456-463.
Gong B, He E, Qiu H, et al. The cation competition and electrostatic theory are equally valid in quantifying the toxicity of trivalent rare earth ions (Y3+ and Ce3+) to Triticum aestivum. Environ Pollut. 2019;250:456-463.
Gong, B., He, E., Qiu, H., Li, J., Ji, J., Peijnenburg, W. J. G. M., Liu, Y., Zhao, L., & Cao, X. (2019). The cation competition and electrostatic theory are equally valid in quantifying the toxicity of trivalent rare earth ions (Y3+ and Ce3+) to Triticum aestivum. Environmental Pollution (Barking, Essex : 1987), 250, 456-463. https://doi.org/10.1016/j.envpol.2019.04.075
Gong B, et al. The Cation Competition and Electrostatic Theory Are Equally Valid in Quantifying the Toxicity of Trivalent Rare Earth Ions (Y3+ and Ce3+) to Triticum Aestivum. Environ Pollut. 2019;250:456-463. PubMed PMID: 31026692.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The cation competition and electrostatic theory are equally valid in quantifying the toxicity of trivalent rare earth ions (Y3+ and Ce3+) to Triticum aestivum. AU - Gong,Bing, AU - He,Erkai, AU - Qiu,Hao, AU - Li,Jianqiu, AU - Ji,Jie, AU - Peijnenburg,Willie J G M, AU - Liu,Yang, AU - Zhao,Ling, AU - Cao,Xinde, Y1 - 2019/04/17/ PY - 2018/12/26/received PY - 2019/03/12/revised PY - 2019/04/15/accepted PY - 2019/4/27/pubmed PY - 2019/7/26/medline PY - 2019/4/27/entrez KW - Bioavailability KW - Biotic ligand model KW - Electrostatic toxicity model KW - Rare earth elements KW - Toxicity SP - 456 EP - 463 JF - Environmental pollution (Barking, Essex : 1987) JO - Environ Pollut VL - 250 N2 - There is a lack of appropriate models to delineate the toxicity of rare earth elements (REEs) while taking into account the factors that affect bioavailability. Here, standardized wheat (Triticum aestivum L.) root elongation tests were conducted to examine the impact of exposure conditions (i.e., varying Ca, Mg, Na, K and pH levels) on Y and Ce toxicity. Cation competition and electrostatic theory were examined for their applicability in explaining the observed variations in toxicity. Only Ca2+ and Mg2+ significantly alleviated the toxicity of Y3+ and Ce3+, while Na+, K+ and H+ showed no significant effects. Based on the cation competition, the derived binding constants for the hypothetical biotic ligands of wheat logKCaBL, logKMgBL, logKYBL, and logKCeBL were 3.87, 3.59, 6.70, and 6.48, respectively. The biotic ligand model (BLM) succeeded in predicting toxicities of Y and Ce, with more than 93% of the variance in toxicity explained. Given the BLM requires large data sets for deriving model parameters, attempts were further made to explore a simpler electrostatic based model to quantify REEs toxicity. The results demonstrated that the predictive capacity of the electrostatic approach, which considers ion activities at the plasma membrane surface, was comparable to that of BLM with at least 87% of the variations in toxicity explained. This suggested that the electrostatic theory can serve as a surrogate to BLM in modeling Y and Ce toxicities. Therefore, we recommend the BLM and electrostatic-based model as effective approaches to incorporate bioavailability in quantifying REEs toxicity in the presence of various levels of other major cations. SN - 1873-6424 UR - https://www.unboundmedicine.com/medline/citation/31026692/The_cation_competition_and_electrostatic_theory_are_equally_valid_in_quantifying_the_toxicity_of_trivalent_rare_earth_ions__Y3+_and_Ce3+__to_Triticum_aestivum_ DB - PRIME DP - Unbound Medicine ER -