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[Primary angiitis of the central nervous system with cerebral infarction and spinal hemorrhage].
Rinsho Shinkeigaku. 2019 May 28; 59(5):268-273.RS

Abstract

A 61-year-old woman presented with acute intense lower back pain and weakness in her left leg. She also presented with throbbing headache on the same day. On admission, muscle weakness in her left leg, lower left quadrantanopia and left lower extremity deep sensory disturbance were observed. Laboratory data showed no coagulopathy and autoimmune antibody was negative. Cerebrospinal fluid examination showed bloody and inflammatory findings. Brain MRI revealed cerebral infarction with multiple intracranial arterial stenosis and convexal subarachnoid hemorrhage. Spinal MRI revealed spinal hemorrhage in the cervical, thoracic, and part of the lumbar spine. Because these lesions occurred simultaneously, we made a diagnosis of vasculitis. After high dose corticosteroids therapy was undertaken, the multiple arterial stenosis improved. Primary angiitis of the central nervous system is sometimes difficult to distinguish from reversible cerebral vasoconstriction syndrome in its initial stage; although symptoms, examination findings and treatment differ in both.

Authors+Show Affiliations

Department of Neurology, Kurashiki Central Hospital.Department of Neurology, Kurashiki Central Hospital.Department of Neurology, Kurashiki Central Hospital.

Pub Type(s)

Case Reports
Journal Article

Language

jpn

PubMed ID

31061305

Citation

Wada, Takafumi, et al. "[Primary Angiitis of the Central Nervous System With Cerebral Infarction and Spinal Hemorrhage]." Rinsho Shinkeigaku = Clinical Neurology, vol. 59, no. 5, 2019, pp. 268-273.
Wada T, Kitaguchi H, Shindo K. [Primary angiitis of the central nervous system with cerebral infarction and spinal hemorrhage]. Rinsho Shinkeigaku. 2019;59(5):268-273.
Wada, T., Kitaguchi, H., & Shindo, K. (2019). [Primary angiitis of the central nervous system with cerebral infarction and spinal hemorrhage]. Rinsho Shinkeigaku = Clinical Neurology, 59(5), 268-273. https://doi.org/10.5692/clinicalneurol.cn-001288
Wada T, Kitaguchi H, Shindo K. [Primary Angiitis of the Central Nervous System With Cerebral Infarction and Spinal Hemorrhage]. Rinsho Shinkeigaku. 2019 May 28;59(5):268-273. PubMed PMID: 31061305.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Primary angiitis of the central nervous system with cerebral infarction and spinal hemorrhage]. AU - Wada,Takafumi, AU - Kitaguchi,Hiroshi, AU - Shindo,Katsuro, Y1 - 2019/04/26/ PY - 2019/5/8/pubmed PY - 2019/6/20/medline PY - 2019/5/8/entrez KW - primary angiitis of the central nervous system KW - reversible cerebral vasoconstriction syndrome KW - spinal hemorrhage SP - 268 EP - 273 JF - Rinsho shinkeigaku = Clinical neurology JO - Rinsho Shinkeigaku VL - 59 IS - 5 N2 - A 61-year-old woman presented with acute intense lower back pain and weakness in her left leg. She also presented with throbbing headache on the same day. On admission, muscle weakness in her left leg, lower left quadrantanopia and left lower extremity deep sensory disturbance were observed. Laboratory data showed no coagulopathy and autoimmune antibody was negative. Cerebrospinal fluid examination showed bloody and inflammatory findings. Brain MRI revealed cerebral infarction with multiple intracranial arterial stenosis and convexal subarachnoid hemorrhage. Spinal MRI revealed spinal hemorrhage in the cervical, thoracic, and part of the lumbar spine. Because these lesions occurred simultaneously, we made a diagnosis of vasculitis. After high dose corticosteroids therapy was undertaken, the multiple arterial stenosis improved. Primary angiitis of the central nervous system is sometimes difficult to distinguish from reversible cerebral vasoconstriction syndrome in its initial stage; although symptoms, examination findings and treatment differ in both. SN - 1882-0654 UR - https://www.unboundmedicine.com/medline/citation/31061305/[Primary_angiitis_of_the_central_nervous_system_with_cerebral_infarction_and_spinal_hemorrhage]. L2 - https://dx.doi.org/10.5692/clinicalneurol.cn-001288 DB - PRIME DP - Unbound Medicine ER -