Tags

Type your tag names separated by a space and hit enter

Phytochemical screening and evaluation of the antimicrobial and antioxidant activities of Ferula caspica M. Bieb. extracts.
Saudi Pharm J. 2019 May; 27(4):525-531.SP

Abstract

Chloroform, ethyl acetate and methanol extracts from the aerial parts of Ferula caspica M. Bieb. were tested for their antioxidant capacities by CUPRAC, ABTS, FRAP, Folin-Ciocalteu and aluminum chloride methods and for antimicrobial activities by the broth microdilution method. Chloroform and ethyl acetate extracts showed the highest antioxidant capacity and antimicrobial activity. Three known sesquiterpene derivatives; 1-(2',4'-dihydroxyphenyl)-3,7,11-trimethyl-3-vinyl-6(E),10-dodecadien-1-one (1), 2,3-dihydro-7-hydroxy-2,3-dimethyl-2-[4',8'-dimethyl-3',7'-nonadienyl]-furo[3,2,c]coumarin (2), 2,3-dihydro-7-hydroxy-2,3-dimethyl-3-[4',8'-dimethyl-3',7'-nonadienyl]-furo[3,2,c]coumarin(3); phenylpropanoid; laserine/2-epilaserine (4/5) and steroid mixtures; stigmasterol and β-sitosterol (6/7) were isolated from chloroform extract; three known flavonoids; kaempferol-3-O-β-glucopyranoside (8), kaempferol-3-O-α-rhamnopyranoside (9), quercetin-3-O-β-glucopyranoside (10), and one benzoic acid derivative; 2,4-dihydroxybenzoic acid (11) were isolated from the ethyl acetate extract. The structures were elucidated by spectroscopic methods.

Links

PMC Free PDF

Authors+Show Affiliations

Kahraman C
Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.
Topcu G
Department of Pharmacognosy, Faculty of Pharmacy, Bezmialem Vakif University, İstanbul, Turkey.
Bedir E
Department of Bioengineering, Faculty of Engineering, İzmir Institute of Technology, İzmir, Turkey.
Tatli II
Department of Pharmaceutical Botany, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.
Ekizoglu M
Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.
Akdemir ZS
Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31061621

Citation

Kahraman, Cigdem, et al. "Phytochemical Screening and Evaluation of the Antimicrobial and Antioxidant Activities of Ferula Caspica M. Bieb. Extracts." Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical Society, vol. 27, no. 4, 2019, pp. 525-531.
Kahraman C, Topcu G, Bedir E, et al. Phytochemical screening and evaluation of the antimicrobial and antioxidant activities of Ferula caspica M. Bieb. extracts. Saudi Pharm J. 2019;27(4):525-531.
Kahraman, C., Topcu, G., Bedir, E., Tatli, I. I., Ekizoglu, M., & Akdemir, Z. S. (2019). Phytochemical screening and evaluation of the antimicrobial and antioxidant activities of Ferula caspica M. Bieb. extracts. Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical Society, 27(4), 525-531. https://doi.org/10.1016/j.jsps.2019.01.016
Kahraman C, et al. Phytochemical Screening and Evaluation of the Antimicrobial and Antioxidant Activities of Ferula Caspica M. Bieb. Extracts. Saudi Pharm J. 2019;27(4):525-531. PubMed PMID: 31061621.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Phytochemical screening and evaluation of the antimicrobial and antioxidant activities of Ferula caspica M. Bieb. extracts. AU - Kahraman,Cigdem, AU - Topcu,Gulacti, AU - Bedir,Erdal, AU - Tatli,I Irem, AU - Ekizoglu,Melike, AU - Akdemir,Zeliha S, Y1 - 2019/02/02/ PY - 2018/10/17/received PY - 2019/01/27/accepted PY - 2019/5/8/entrez PY - 2019/5/8/pubmed PY - 2019/5/8/medline KW - Antimicrobial KW - Antioxidant KW - Constituents KW - Ferula caspica KW - NMR SP - 525 EP - 531 JF - Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society JO - Saudi Pharm J VL - 27 IS - 4 N2 - Chloroform, ethyl acetate and methanol extracts from the aerial parts of Ferula caspica M. Bieb. were tested for their antioxidant capacities by CUPRAC, ABTS, FRAP, Folin-Ciocalteu and aluminum chloride methods and for antimicrobial activities by the broth microdilution method. Chloroform and ethyl acetate extracts showed the highest antioxidant capacity and antimicrobial activity. Three known sesquiterpene derivatives; 1-(2',4'-dihydroxyphenyl)-3,7,11-trimethyl-3-vinyl-6(E),10-dodecadien-1-one (1), 2,3-dihydro-7-hydroxy-2,3-dimethyl-2-[4',8'-dimethyl-3',7'-nonadienyl]-furo[3,2,c]coumarin (2), 2,3-dihydro-7-hydroxy-2,3-dimethyl-3-[4',8'-dimethyl-3',7'-nonadienyl]-furo[3,2,c]coumarin(3); phenylpropanoid; laserine/2-epilaserine (4/5) and steroid mixtures; stigmasterol and β-sitosterol (6/7) were isolated from chloroform extract; three known flavonoids; kaempferol-3-O-β-glucopyranoside (8), kaempferol-3-O-α-rhamnopyranoside (9), quercetin-3-O-β-glucopyranoside (10), and one benzoic acid derivative; 2,4-dihydroxybenzoic acid (11) were isolated from the ethyl acetate extract. The structures were elucidated by spectroscopic methods. SN - 1319-0164 UR - https://www.unboundmedicine.com/medline/citation/31061621/Phytochemical_screening_and_evaluation_of_the_antimicrobial_and_antioxidant_activities_of_Ferula_caspica_M__Bieb__extracts_ DB - PRIME DP - Unbound Medicine ER -