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Excellent response to mesotherapy as adjunctive treatment in male androgenetic alopecia.
J Cosmet Dermatol. 2020 Jan; 19(1):75-77.JC

Abstract

Androgenetic alopecia (AGA) is the most common type of alopecia. Currently, only topical minoxidil and oral finasteride, for men, are approved for its treatment. We report a case of a patient with male pattern AGA treated with topical minoxidil and oral finasteride for 2 years, with partial improvement. At this point, we added mesotherapy to the previous treatment. The patient had 20 sessions of sterile mesotherapy blend, containing minoxidil, finasteride, biotin, and D-panthenol. We did the injections every two weeks and made the response assessment with global clinical photographs at the 10th and the 20th sessions when we noted a significant visible improvement in hair density and thickness. Mesotherapy or intradermotherapy is defined as a technique that involves the use of multiple intradermal injections of a mixture of compounds in low doses, at many points, near/over the affected sites. In our case, the patient had an excellent response to intradermotherapy as an adjunctive treatment, with no side effects. Although we still need additional clinical trials to standardize the therapy and treatment guidelines, mesotherapy seems to be a therapeutic option in the treatment of AGA, especially if the procedure happens in a medical facility, with correct indication and adequate execution of this promising technique.

Authors+Show Affiliations

Post-Graduate Program in Medical Sciences of the Hospital Universitário Pedro Ernesto, Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, Brazil. Hospital Naval Marcílio Dias, Rio de Janeiro, Brazil.Hospital Naval Marcílio Dias, Rio de Janeiro, Brazil.Hospital Naval Marcílio Dias, Rio de Janeiro, Brazil.Hospital Naval Marcílio Dias, Rio de Janeiro, Brazil.Post-Graduate Program in Medical Sciences of the Hospital Universitário Pedro Ernesto, Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, Brazil. Hospital Naval Marcílio Dias, Rio de Janeiro, Brazil.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

31066492

Citation

Melo, Daniel Fernandes, et al. "Excellent Response to Mesotherapy as Adjunctive Treatment in Male Androgenetic Alopecia." Journal of Cosmetic Dermatology, vol. 19, no. 1, 2020, pp. 75-77.
Melo DF, de Mattos Barreto T, Plata GT, et al. Excellent response to mesotherapy as adjunctive treatment in male androgenetic alopecia. J Cosmet Dermatol. 2020;19(1):75-77.
Melo, D. F., de Mattos Barreto, T., Plata, G. T., Araujo, L. R., & Tortelly, V. D. (2020). Excellent response to mesotherapy as adjunctive treatment in male androgenetic alopecia. Journal of Cosmetic Dermatology, 19(1), 75-77. https://doi.org/10.1111/jocd.12983
Melo DF, et al. Excellent Response to Mesotherapy as Adjunctive Treatment in Male Androgenetic Alopecia. J Cosmet Dermatol. 2020;19(1):75-77. PubMed PMID: 31066492.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Excellent response to mesotherapy as adjunctive treatment in male androgenetic alopecia. AU - Melo,Daniel Fernandes, AU - de Mattos Barreto,Taynara, AU - Plata,Glaura Tinoco, AU - Araujo,Leonardo Rotolo, AU - Tortelly,Violeta Duarte, Y1 - 2019/05/08/ PY - 2019/02/17/received PY - 2019/04/07/revised PY - 2019/04/11/accepted PY - 2019/5/9/pubmed PY - 2020/11/20/medline PY - 2019/5/9/entrez KW - alopecia KW - androgenetic KW - hair loss KW - intradermal injection KW - mesotherapy SP - 75 EP - 77 JF - Journal of cosmetic dermatology JO - J Cosmet Dermatol VL - 19 IS - 1 N2 - Androgenetic alopecia (AGA) is the most common type of alopecia. Currently, only topical minoxidil and oral finasteride, for men, are approved for its treatment. We report a case of a patient with male pattern AGA treated with topical minoxidil and oral finasteride for 2 years, with partial improvement. At this point, we added mesotherapy to the previous treatment. The patient had 20 sessions of sterile mesotherapy blend, containing minoxidil, finasteride, biotin, and D-panthenol. We did the injections every two weeks and made the response assessment with global clinical photographs at the 10th and the 20th sessions when we noted a significant visible improvement in hair density and thickness. Mesotherapy or intradermotherapy is defined as a technique that involves the use of multiple intradermal injections of a mixture of compounds in low doses, at many points, near/over the affected sites. In our case, the patient had an excellent response to intradermotherapy as an adjunctive treatment, with no side effects. Although we still need additional clinical trials to standardize the therapy and treatment guidelines, mesotherapy seems to be a therapeutic option in the treatment of AGA, especially if the procedure happens in a medical facility, with correct indication and adequate execution of this promising technique. SN - 1473-2165 UR - https://www.unboundmedicine.com/medline/citation/31066492/ L2 - https://doi.org/10.1111/jocd.12983 DB - PRIME DP - Unbound Medicine ER -