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Causes and consequences of reciprocal translocations on sex chromosomes.
Mol Ecol 2019; 28(8):1863-1865ME

Abstract

Under XY sex determination, the Y chromosome is only inherited via males, whereas the X chromosome is predominantly found in females. Thus, it is favourable when alleles with high male fitness become associated with the Y chromosome and when alleles with high female fitness become associated with the X chromosome. These favourable associations can be strengthened through linkage. Rearrangements, such as inversions and sex chromosome-autosome fusions, can increase linkage and thereby become favoured (Charlesworth, 2017). In a From the Cover article in this issue of Molecular Ecology, Toups, Rodrigues, Perrin, and Kirkpatrick (2019) present the first genomic analysis of a sex chromosome reciprocal translocation, a particularly dramatic chromosomal rearrangement that modifies linkage with the sex chromosome. As a result of reciprocal translocation, one studied population of the common frog (Rana temporaria, Figure 1) displays a remarkable sex-determining system in which there are two physically unlinked sex chromosomes that are exclusively cotransmitted (Figure 2a).

Authors+Show Affiliations

UCL Genetics Institute, Department of Genetics, Evolution and Environment, University College London, London, UK.

Pub Type(s)

News
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

31099463

Citation

Scott, Michael F.. "Causes and Consequences of Reciprocal Translocations On Sex Chromosomes." Molecular Ecology, vol. 28, no. 8, 2019, pp. 1863-1865.
Scott MF. Causes and consequences of reciprocal translocations on sex chromosomes. Mol Ecol. 2019;28(8):1863-1865.
Scott, M. F. (2019). Causes and consequences of reciprocal translocations on sex chromosomes. Molecular Ecology, 28(8), pp. 1863-1865. doi:10.1111/mec.15064.
Scott MF. Causes and Consequences of Reciprocal Translocations On Sex Chromosomes. Mol Ecol. 2019;28(8):1863-1865. PubMed PMID: 31099463.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Causes and consequences of reciprocal translocations on sex chromosomes. A1 - Scott,Michael F, Y1 - 2019/05/05/ PY - 2019/01/31/received PY - 2019/02/23/revised PY - 2019/02/25/accepted PY - 2019/5/18/entrez PY - 2019/5/18/pubmed PY - 2019/5/18/medline SP - 1863 EP - 1865 JF - Molecular ecology JO - Mol. Ecol. VL - 28 IS - 8 N2 - Under XY sex determination, the Y chromosome is only inherited via males, whereas the X chromosome is predominantly found in females. Thus, it is favourable when alleles with high male fitness become associated with the Y chromosome and when alleles with high female fitness become associated with the X chromosome. These favourable associations can be strengthened through linkage. Rearrangements, such as inversions and sex chromosome-autosome fusions, can increase linkage and thereby become favoured (Charlesworth, 2017). In a From the Cover article in this issue of Molecular Ecology, Toups, Rodrigues, Perrin, and Kirkpatrick (2019) present the first genomic analysis of a sex chromosome reciprocal translocation, a particularly dramatic chromosomal rearrangement that modifies linkage with the sex chromosome. As a result of reciprocal translocation, one studied population of the common frog (Rana temporaria, Figure 1) displays a remarkable sex-determining system in which there are two physically unlinked sex chromosomes that are exclusively cotransmitted (Figure 2a). SN - 1365-294X UR - https://www.unboundmedicine.com/medline/citation/31099463/Causes_and_consequences_of_reciprocal_translocations_on_sex_chromosomes L2 - https://doi.org/10.1111/mec.15064 DB - PRIME DP - Unbound Medicine ER -
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