Tags

Type your tag names separated by a space and hit enter

Biomarkers of Nutrition and Health: New Tools for New Approaches.

Abstract

A main challenge in nutritional studies is the valid and reliable assessment of food intake, as well as its effects on the body. Generally, food intake measurement is based on self-reported dietary intake questionnaires, which have inherent limitations. They can be overcome by the use of biomarkers, capable of objectively assessing food consumption without the bias of self-reported dietary assessment. Another major goal is to determine the biological effects of foods and their impact on health. Systems analysis of dynamic responses may help to identify biomarkers indicative of intake and effects on the body at the same time, possibly in relation to individuals' health/disease states. Such biomarkers could be used to quantify intake and validate intake questionnaires, analyse physiological or pathological responses to certain food components or diets, identify persons with specific dietary deficiency, provide information on inter-individual variations or help to formulate personalized dietary recommendations to achieve optimal health for particular phenotypes, currently referred as "precision nutrition." In this regard, holistic approaches using global analysis methods (omics approaches), capable of gathering high amounts of data, appear to be very useful to identify new biomarkers and to enhance our understanding of the role of food in health and disease.

Links

  • PMC Free PDF
  • PMC Free Full Text
  • FREE Publisher Full Text
  • Authors+Show Affiliations

    ,

    Laboratory of Molecular Biology, Nutrition and Biotechnology (Group of Nutrigenomics and Obesity), CIBER de Fisiopatología de la Obesidad y Nutrición (CIBERobn) and Instituto de Investigación Sanitaria Illes Balears (IdISBa), University of the Balearic Islands, ES-07122 Palma de Mallorca, Spain. cati.pico@uib.es.

    ,

    Laboratory of Molecular Biology, Nutrition and Biotechnology (Group of Nutrigenomics and Obesity), CIBER de Fisiopatología de la Obesidad y Nutrición (CIBERobn) and Instituto de Investigación Sanitaria Illes Balears (IdISBa), University of the Balearic Islands, ES-07122 Palma de Mallorca, Spain. francisca.serra@uib.es.

    ,

    Laboratory of Molecular Biology, Nutrition and Biotechnology (Group of Nutrigenomics and Obesity), CIBER de Fisiopatología de la Obesidad y Nutrición (CIBERobn) and Instituto de Investigación Sanitaria Illes Balears (IdISBa), University of the Balearic Islands, ES-07122 Palma de Mallorca, Spain. amrodriguez@uib.es.

    ,

    Human and Animal Physiology, Wageningen University, PO Box 338, 6700 AH Wageningen, The Netherlands. jaap.keijer@wur.nl.

    Laboratory of Molecular Biology, Nutrition and Biotechnology (Group of Nutrigenomics and Obesity), CIBER de Fisiopatología de la Obesidad y Nutrición (CIBERobn) and Instituto de Investigación Sanitaria Illes Balears (IdISBa), University of the Balearic Islands, ES-07122 Palma de Mallorca, Spain. andreu.palou@uib.es.

    Source

    Nutrients 11:5 2019 May 16 pg

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    31100942

    Citation

    Picó, Catalina, et al. "Biomarkers of Nutrition and Health: New Tools for New Approaches." Nutrients, vol. 11, no. 5, 2019.
    Picó C, Serra F, Rodríguez AM, et al. Biomarkers of Nutrition and Health: New Tools for New Approaches. Nutrients. 2019;11(5).
    Picó, C., Serra, F., Rodríguez, A. M., Keijer, J., & Palou, A. (2019). Biomarkers of Nutrition and Health: New Tools for New Approaches. Nutrients, 11(5), doi:10.3390/nu11051092.
    Picó C, et al. Biomarkers of Nutrition and Health: New Tools for New Approaches. Nutrients. 2019 May 16;11(5) PubMed PMID: 31100942.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Biomarkers of Nutrition and Health: New Tools for New Approaches. AU - Picó,Catalina, AU - Serra,Francisca, AU - Rodríguez,Ana María, AU - Keijer,Jaap, AU - Palou,Andreu, Y1 - 2019/05/16/ PY - 2019/04/04/received PY - 2019/05/07/revised PY - 2019/05/08/accepted PY - 2019/5/19/entrez PY - 2019/5/19/pubmed PY - 2019/5/19/medline KW - food intake assessment KW - integrative biomarkers KW - omics technologies KW - precision nutrition JF - Nutrients JO - Nutrients VL - 11 IS - 5 N2 - A main challenge in nutritional studies is the valid and reliable assessment of food intake, as well as its effects on the body. Generally, food intake measurement is based on self-reported dietary intake questionnaires, which have inherent limitations. They can be overcome by the use of biomarkers, capable of objectively assessing food consumption without the bias of self-reported dietary assessment. Another major goal is to determine the biological effects of foods and their impact on health. Systems analysis of dynamic responses may help to identify biomarkers indicative of intake and effects on the body at the same time, possibly in relation to individuals' health/disease states. Such biomarkers could be used to quantify intake and validate intake questionnaires, analyse physiological or pathological responses to certain food components or diets, identify persons with specific dietary deficiency, provide information on inter-individual variations or help to formulate personalized dietary recommendations to achieve optimal health for particular phenotypes, currently referred as "precision nutrition." In this regard, holistic approaches using global analysis methods (omics approaches), capable of gathering high amounts of data, appear to be very useful to identify new biomarkers and to enhance our understanding of the role of food in health and disease. SN - 2072-6643 UR - https://www.unboundmedicine.com/medline/citation/31100942/Biomarkers_of_Nutrition_and_Health:_New_Tools_for_New_Approaches L2 - http://www.mdpi.com/resolver?pii=nu11051092 DB - PRIME DP - Unbound Medicine ER -