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[Results of the GnRH-TRH and arginine-GnRH-TRH test in females with hyperprolactinemic galactorrhea].
Zentralbl Gynakol. 1987; 109(8):501-9.ZG

Abstract

In 7 patients aged from 21 to 33 years (average age 24.6 years) with hyperprolactinemic galactorrhea a stimulation test with GnRH-TRH or arginine-GnRH-TRH was performed. The serum levels of LH, FSH, PRL, HGH, TSH and total thyroxine (T4) were determined by RIA, the thyroxine binding capacity (TBC) by radio agent assay. The free thyroxine index (FT4-I) was calculated. An adenoma of the pituitary gland was diagnosed in 3 patients by X-ray of sella turcica. In all patients there were disturbances of the menstrual cycle. Independent of the existence of an adenoma of the pituitary gland in all patients with high basal levels. PRL could not have been shown stimulated by TRH. On the other hand it could be shown that despite of high basal PRL-levels in serum there was a normal stimulation of the gonadotrophs in 5 patients. Out of one patient the stimulation of the thyreotropic cells of pituitary by TRH was normal, too, whereas there was no or an inadaquate stimulation of HGH by arginine in all patients.--T4, TBC and FT4-I showed no deviation from the normal range.

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

3111128

Citation

Rudolf, K, et al. "[Results of the GnRH-TRH and arginine-GnRH-TRH Test in Females With Hyperprolactinemic Galactorrhea]." Zentralblatt Fur Gynakologie, vol. 109, no. 8, 1987, pp. 501-9.
Rudolf K, Kunkel S, Rudolf H. [Results of the GnRH-TRH and arginine-GnRH-TRH test in females with hyperprolactinemic galactorrhea]. Zentralbl Gynakol. 1987;109(8):501-9.
Rudolf, K., Kunkel, S., & Rudolf, H. (1987). [Results of the GnRH-TRH and arginine-GnRH-TRH test in females with hyperprolactinemic galactorrhea]. Zentralblatt Fur Gynakologie, 109(8), 501-9.
Rudolf K, Kunkel S, Rudolf H. [Results of the GnRH-TRH and arginine-GnRH-TRH Test in Females With Hyperprolactinemic Galactorrhea]. Zentralbl Gynakol. 1987;109(8):501-9. PubMed PMID: 3111128.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Results of the GnRH-TRH and arginine-GnRH-TRH test in females with hyperprolactinemic galactorrhea]. AU - Rudolf,K, AU - Kunkel,S, AU - Rudolf,H, PY - 1987/1/1/pubmed PY - 1987/1/1/medline PY - 1987/1/1/entrez SP - 501 EP - 9 JF - Zentralblatt fur Gynakologie JO - Zentralbl Gynakol VL - 109 IS - 8 N2 - In 7 patients aged from 21 to 33 years (average age 24.6 years) with hyperprolactinemic galactorrhea a stimulation test with GnRH-TRH or arginine-GnRH-TRH was performed. The serum levels of LH, FSH, PRL, HGH, TSH and total thyroxine (T4) were determined by RIA, the thyroxine binding capacity (TBC) by radio agent assay. The free thyroxine index (FT4-I) was calculated. An adenoma of the pituitary gland was diagnosed in 3 patients by X-ray of sella turcica. In all patients there were disturbances of the menstrual cycle. Independent of the existence of an adenoma of the pituitary gland in all patients with high basal levels. PRL could not have been shown stimulated by TRH. On the other hand it could be shown that despite of high basal PRL-levels in serum there was a normal stimulation of the gonadotrophs in 5 patients. Out of one patient the stimulation of the thyreotropic cells of pituitary by TRH was normal, too, whereas there was no or an inadaquate stimulation of HGH by arginine in all patients.--T4, TBC and FT4-I showed no deviation from the normal range. SN - 0044-4197 UR - https://www.unboundmedicine.com/medline/citation/3111128/[Results_of_the_GnRH_TRH_and_arginine_GnRH_TRH_test_in_females_with_hyperprolactinemic_galactorrhea]_ DB - PRIME DP - Unbound Medicine ER -