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Dermatologically challenging syphilis presentation.
Int J STD AIDS. 2019 06; 30(7):707-709.IJ

Abstract

An atypical early primary syphilis case presentation with multiple umbilicated papular lesions on the penis and a nonreactive syphilis serology was misdiagnosed as molluscum contagiosum. Over a period of eight weeks, prior to dermatologic consultation, the papules enlarged, ulcerated, and healed. New plaque and patch formation on the penis and scrotum led to a differential diagnosis of inverse psoriasis vs. syphilis. Histological examination of a shave biopsy specimen revealed numerous Treponema pallidum organisms and repeat syphilis serological test results confirmed a syphilis diagnosis. Lesions responded to treatment with benzathine penicillin. One must keep a high index of suspicion for syphilis in light of its diverse presentation and increasing incidence.

Authors+Show Affiliations

1 Diamond Head STD Clinic, Hawaii Department of Health, Honolulu, HI, USA. 2 Office of Public Health Studies, University of Hawaii, Honolulu, HI, USA.3 John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, USA.1 Diamond Head STD Clinic, Hawaii Department of Health, Honolulu, HI, USA.1 Diamond Head STD Clinic, Hawaii Department of Health, Honolulu, HI, USA.3 John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, USA.1 Diamond Head STD Clinic, Hawaii Department of Health, Honolulu, HI, USA.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

31112488

Citation

Katz, Alan R., et al. "Dermatologically Challenging Syphilis Presentation." International Journal of STD & AIDS, vol. 30, no. 7, 2019, pp. 707-709.
Katz AR, Johnson DW, Komeya AY, et al. Dermatologically challenging syphilis presentation. Int J STD AIDS. 2019;30(7):707-709.
Katz, A. R., Johnson, D. W., Komeya, A. Y., Tomas, J. E., Namiki, T. S., & Kobayashi, K. (2019). Dermatologically challenging syphilis presentation. International Journal of STD & AIDS, 30(7), 707-709. https://doi.org/10.1177/0956462418817636
Katz AR, et al. Dermatologically Challenging Syphilis Presentation. Int J STD AIDS. 2019;30(7):707-709. PubMed PMID: 31112488.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dermatologically challenging syphilis presentation. AU - Katz,Alan R, AU - Johnson,Douglas W, AU - Komeya,Alan Y, AU - Tomas,Juval E, AU - Namiki,Thomas S, AU - Kobayashi,Kozue, Y1 - 2019/01/09/ PY - 2019/5/22/entrez PY - 2019/5/22/pubmed PY - 2019/11/19/medline KW - Syphilis KW - chancre KW - dermatology diagnosis SP - 707 EP - 709 JF - International journal of STD & AIDS JO - Int J STD AIDS VL - 30 IS - 7 N2 - An atypical early primary syphilis case presentation with multiple umbilicated papular lesions on the penis and a nonreactive syphilis serology was misdiagnosed as molluscum contagiosum. Over a period of eight weeks, prior to dermatologic consultation, the papules enlarged, ulcerated, and healed. New plaque and patch formation on the penis and scrotum led to a differential diagnosis of inverse psoriasis vs. syphilis. Histological examination of a shave biopsy specimen revealed numerous Treponema pallidum organisms and repeat syphilis serological test results confirmed a syphilis diagnosis. Lesions responded to treatment with benzathine penicillin. One must keep a high index of suspicion for syphilis in light of its diverse presentation and increasing incidence. SN - 1758-1052 UR - https://www.unboundmedicine.com/medline/citation/31112488/Dermatologically_challenging_syphilis_presentation L2 - http://journals.sagepub.com/doi/full/10.1177/0956462418817636?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -