Tags

Type your tag names separated by a space and hit enter

Glucose and lipid metabolism with triphasic oral contraceptives in women with history of gestational diabetes.
Contraception. 1987 Mar; 35(3):257-69.C

Abstract

The glucose and lipid metabolism in a group of women with previous history of gestational diabetes were evaluated before and after 6 months treatment with a low-dose triphasic oral contraceptives pill (TP). This group was compared with a control group of women, also with history of gestational diabetes, using intrauterine devices (IUD). In the TP group, 26.7% of the women developed impaired glucose tolerance which reverted to normal in all but one after cessation of the TP. The IUD group showed no change in glucose tolerance. The integrated insulin response to a 75g OGTT in the TP group increased by 48.3% at 6 months compared with an increase of 23.4% for the same period in the IUD group. In the TP group there was a significant decrease in serum total cholesterol without changes in HDL-cholesterol and triglycerides level. We conclude that even low-dose triphasic oral contraceptive pills can cause glucose intolerance in women with previous gestational diabetes mellitus.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

3111786

Citation

Kung, A W., et al. "Glucose and Lipid Metabolism With Triphasic Oral Contraceptives in Women With History of Gestational Diabetes." Contraception, vol. 35, no. 3, 1987, pp. 257-69.
Kung AW, Ma JT, Wong VC, et al. Glucose and lipid metabolism with triphasic oral contraceptives in women with history of gestational diabetes. Contraception. 1987;35(3):257-69.
Kung, A. W., Ma, J. T., Wong, V. C., Li, D. F., Ng, M. M., Wang, C. C., Lam, K. S., Young, R. T., & Ma, H. K. (1987). Glucose and lipid metabolism with triphasic oral contraceptives in women with history of gestational diabetes. Contraception, 35(3), 257-69.
Kung AW, et al. Glucose and Lipid Metabolism With Triphasic Oral Contraceptives in Women With History of Gestational Diabetes. Contraception. 1987;35(3):257-69. PubMed PMID: 3111786.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Glucose and lipid metabolism with triphasic oral contraceptives in women with history of gestational diabetes. AU - Kung,A W, AU - Ma,J T, AU - Wong,V C, AU - Li,D F, AU - Ng,M M, AU - Wang,C C, AU - Lam,K S, AU - Young,R T, AU - Ma,H K, PY - 1987/3/1/pubmed PY - 1987/3/1/medline PY - 1987/3/1/entrez KW - Biology KW - Carbohydrate Metabolic Effects KW - Comparative Studies KW - Contraception KW - Contraceptive Agents KW - Contraceptive Agents, Female KW - Contraceptive Methods--pharmacodynamics KW - Diabetes Mellitus KW - Diseases KW - Endocrine Effects KW - Endocrine System KW - Family Planning KW - Glucose Metabolism Effects KW - Lipid Metabolic Effects KW - Lipids KW - Metabolic Effects KW - Oral Contraceptives, Low-dose--pharmacodynamics KW - Oral Contraceptives--pharmacodynamics KW - Physiology KW - Research Methodology KW - Studies SP - 257 EP - 69 JF - Contraception JO - Contraception VL - 35 IS - 3 N2 - The glucose and lipid metabolism in a group of women with previous history of gestational diabetes were evaluated before and after 6 months treatment with a low-dose triphasic oral contraceptives pill (TP). This group was compared with a control group of women, also with history of gestational diabetes, using intrauterine devices (IUD). In the TP group, 26.7% of the women developed impaired glucose tolerance which reverted to normal in all but one after cessation of the TP. The IUD group showed no change in glucose tolerance. The integrated insulin response to a 75g OGTT in the TP group increased by 48.3% at 6 months compared with an increase of 23.4% for the same period in the IUD group. In the TP group there was a significant decrease in serum total cholesterol without changes in HDL-cholesterol and triglycerides level. We conclude that even low-dose triphasic oral contraceptive pills can cause glucose intolerance in women with previous gestational diabetes mellitus. SN - 0010-7824 UR - https://www.unboundmedicine.com/medline/citation/3111786/Glucose_and_lipid_metabolism_with_triphasic_oral_contraceptives_in_women_with_history_of_gestational_diabetes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0010-7824(87)90027-8 DB - PRIME DP - Unbound Medicine ER -