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[Fructose and sorbitol as energy-supplying substrates for parenteral nutrition].
Infusionsther Klin Ernahr. 1987 Jun; 14(3):98-109.IK

Abstract

The glucose substitutes (fructose, sorbitol, xylitol) have significant metabolic advantages in stress situations as compared to glucose. Side-effects are usually not to be expected if indications and dosage are carefully determined. The only contraindication for fructose and for sorbitol is hereditary fructose intolerance. However, this metabolic disease should be known to physicians who are involved in parenteral nutrition. Fructose intolerance might also be diagnosed by the metabolic alterations caused by fructose or by sorbitol administration in such patients. It was shown repeatedly during the last few decades that glucose formed in the liver during metabolism of glucose substitutes and delivered to the circulation is obviously metabolized without an increase in blood glucose concentration and without additional requirement of insulin. No explanation for this amazing, long-observed metabolic effect is known to date. These reproducible results should stimulate new investigations. Such effects should not be rejected or questioned because they do not fit into the hypotheses.

Authors

No affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

3112007

Citation

Förster, H. "[Fructose and Sorbitol as Energy-supplying Substrates for Parenteral Nutrition]." Infusionstherapie Und Klinische Ernahrung, vol. 14, no. 3, 1987, pp. 98-109.
Förster H. [Fructose and sorbitol as energy-supplying substrates for parenteral nutrition]. Infusionsther Klin Ernahr. 1987;14(3):98-109.
Förster, H. (1987). [Fructose and sorbitol as energy-supplying substrates for parenteral nutrition]. Infusionstherapie Und Klinische Ernahrung, 14(3), 98-109.
Förster H. [Fructose and Sorbitol as Energy-supplying Substrates for Parenteral Nutrition]. Infusionsther Klin Ernahr. 1987;14(3):98-109. PubMed PMID: 3112007.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Fructose and sorbitol as energy-supplying substrates for parenteral nutrition]. A1 - Förster,H, PY - 1987/6/1/pubmed PY - 1987/6/1/medline PY - 1987/6/1/entrez SP - 98 EP - 109 JF - Infusionstherapie und klinische Ernahrung JO - Infusionsther Klin Ernahr VL - 14 IS - 3 N2 - The glucose substitutes (fructose, sorbitol, xylitol) have significant metabolic advantages in stress situations as compared to glucose. Side-effects are usually not to be expected if indications and dosage are carefully determined. The only contraindication for fructose and for sorbitol is hereditary fructose intolerance. However, this metabolic disease should be known to physicians who are involved in parenteral nutrition. Fructose intolerance might also be diagnosed by the metabolic alterations caused by fructose or by sorbitol administration in such patients. It was shown repeatedly during the last few decades that glucose formed in the liver during metabolism of glucose substitutes and delivered to the circulation is obviously metabolized without an increase in blood glucose concentration and without additional requirement of insulin. No explanation for this amazing, long-observed metabolic effect is known to date. These reproducible results should stimulate new investigations. Such effects should not be rejected or questioned because they do not fit into the hypotheses. SN - 0378-0791 UR - https://www.unboundmedicine.com/medline/citation/3112007/[Fructose_and_sorbitol_as_energy_supplying_substrates_for_parenteral_nutrition]_ DB - PRIME DP - Unbound Medicine ER -