Tags

Type your tag names separated by a space and hit enter

Functional and morphological results of treatment of macula-on and macula-off rhegmatogenous retinal detachment with pars plana vitrectomy and sulfur hexafluoride gas tamponade.
BMC Ophthalmol 2019; 19(1):118BO

Abstract

BACKGROUND

To examine morphological and functional results after pars plana vitrectomy (PPV) with sulfur hexafluoride (SF6) gas tamponade due to macula-on and macula-off rhegmatogenous retinal detachment (RRD) during 6 months of the follow-up.

METHODS

The study included 62 eyes that underwent successful PPV with SF6 tamponade with macula-on (34 eyes) and macula-off (28 eyes) RRD preoperatively. The best-corrected visual acuity (BCVA), Amsler test, M-charts, optical coherence tomography (OCT) and microperimetry were performed at 1, 3 and 6 months postoperatively.

RESULTS

Results of the Amsler test were abnormal postoperatively in 54% of the patients in the group with macula-off and in 32% of the patients with macula-on RRD. Horizontal M-charts improved significantly from 0.33 to 0.2, vertical M-charts- from 0.29 to 0.17 during 6 months of the follow-up. There was a significant increase in the central retinal thickness (CRT) and average thickness (AT) between follow-up examinations only in the macula-off group. 29 of 62 eyes (47%) after surgery (equally with macula-on and macula-off RRD) showed morphological changes in OCT in the macular region, as epiretinal membrane, macular edema, subretinal fluid or alterations of the outer layers of the retina. The average threshold in microperimetry increased significantly within both groups during the follow-up.

CONCLUSION

Both horizontal and vertical M-charts scores, as were as microperimetry sensitivity improved significantly during the 6 months of the follow-up both in macula-on and macula-off group. Although PPV with SF6 gas tamponade was successful, almost half of eyes revealed anatomical changes in the macular region in OCT both with macula-on and macula-off group.

TRIAL REGISTRATION

Current Controlled Trials NCT03902795 registered on 03/04/2019. Retrospectively registered.

Authors+Show Affiliations

Department of General Ophthalmology, Medical University of Lublin, Poland, ul. Chmielna 1, 20-079, Lublin, Poland.Department of General Ophthalmology, Medical University of Lublin, Poland, ul. Chmielna 1, 20-079, Lublin, Poland. katarzynanowomiejska@mailcity.com.Department of General Ophthalmology, Medical University of Lublin, Poland, ul. Chmielna 1, 20-079, Lublin, Poland.Department of Mathematics and Medical Biostatistics, Medical University, Lublin, Poland.Department of General Ophthalmology, Medical University of Lublin, Poland, ul. Chmielna 1, 20-079, Lublin, Poland. Department of Ophthalmology, University of Catania, Catania, Italy.Department of Ophthalmology, University of Catania, Catania, Italy.Department of General Ophthalmology, Medical University of Lublin, Poland, ul. Chmielna 1, 20-079, Lublin, Poland. University Eye Hospital, Rostock, Germany.Department of General Ophthalmology, Medical University of Lublin, Poland, ul. Chmielna 1, 20-079, Lublin, Poland. Department of Experimental Pharmacology, Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31126280

Citation

Borowicz, Dorota, et al. "Functional and Morphological Results of Treatment of Macula-on and Macula-off Rhegmatogenous Retinal Detachment With Pars Plana Vitrectomy and Sulfur Hexafluoride Gas Tamponade." BMC Ophthalmology, vol. 19, no. 1, 2019, p. 118.
Borowicz D, Nowomiejska K, Nowakowska D, et al. Functional and morphological results of treatment of macula-on and macula-off rhegmatogenous retinal detachment with pars plana vitrectomy and sulfur hexafluoride gas tamponade. BMC Ophthalmol. 2019;19(1):118.
Borowicz, D., Nowomiejska, K., Nowakowska, D., Brzozowska, A., Toro, M. D., Avitabile, T., ... Rejdak, R. (2019). Functional and morphological results of treatment of macula-on and macula-off rhegmatogenous retinal detachment with pars plana vitrectomy and sulfur hexafluoride gas tamponade. BMC Ophthalmology, 19(1), p. 118. doi:10.1186/s12886-019-1120-3.
Borowicz D, et al. Functional and Morphological Results of Treatment of Macula-on and Macula-off Rhegmatogenous Retinal Detachment With Pars Plana Vitrectomy and Sulfur Hexafluoride Gas Tamponade. BMC Ophthalmol. 2019 May 24;19(1):118. PubMed PMID: 31126280.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Functional and morphological results of treatment of macula-on and macula-off rhegmatogenous retinal detachment with pars plana vitrectomy and sulfur hexafluoride gas tamponade. AU - Borowicz,Dorota, AU - Nowomiejska,Katarzyna, AU - Nowakowska,Dominika, AU - Brzozowska,Agnieszka, AU - Toro,Mario D, AU - Avitabile,Teresio, AU - Jünemann,Anselm G, AU - Rejdak,Robert, Y1 - 2019/05/24/ PY - 2018/09/27/received PY - 2019/05/03/accepted PY - 2019/5/26/entrez PY - 2019/5/28/pubmed PY - 2019/6/5/medline KW - M-charts KW - Metamorphopsia KW - Microperimetry KW - Rhegmatogenous retinal detachment SP - 118 EP - 118 JF - BMC ophthalmology JO - BMC Ophthalmol VL - 19 IS - 1 N2 - BACKGROUND: To examine morphological and functional results after pars plana vitrectomy (PPV) with sulfur hexafluoride (SF6) gas tamponade due to macula-on and macula-off rhegmatogenous retinal detachment (RRD) during 6 months of the follow-up. METHODS: The study included 62 eyes that underwent successful PPV with SF6 tamponade with macula-on (34 eyes) and macula-off (28 eyes) RRD preoperatively. The best-corrected visual acuity (BCVA), Amsler test, M-charts, optical coherence tomography (OCT) and microperimetry were performed at 1, 3 and 6 months postoperatively. RESULTS: Results of the Amsler test were abnormal postoperatively in 54% of the patients in the group with macula-off and in 32% of the patients with macula-on RRD. Horizontal M-charts improved significantly from 0.33 to 0.2, vertical M-charts- from 0.29 to 0.17 during 6 months of the follow-up. There was a significant increase in the central retinal thickness (CRT) and average thickness (AT) between follow-up examinations only in the macula-off group. 29 of 62 eyes (47%) after surgery (equally with macula-on and macula-off RRD) showed morphological changes in OCT in the macular region, as epiretinal membrane, macular edema, subretinal fluid or alterations of the outer layers of the retina. The average threshold in microperimetry increased significantly within both groups during the follow-up. CONCLUSION: Both horizontal and vertical M-charts scores, as were as microperimetry sensitivity improved significantly during the 6 months of the follow-up both in macula-on and macula-off group. Although PPV with SF6 gas tamponade was successful, almost half of eyes revealed anatomical changes in the macular region in OCT both with macula-on and macula-off group. TRIAL REGISTRATION: Current Controlled Trials NCT03902795 registered on 03/04/2019. Retrospectively registered. SN - 1471-2415 UR - https://www.unboundmedicine.com/medline/citation/31126280/Functional_and_morphological_results_of_treatment_of_macula_on_and_macula_off_rhegmatogenous_retinal_detachment_with_pars_plana_vitrectomy_and_sulfur_hexafluoride_gas_tamponade_ L2 - https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12886-019-1120-3 DB - PRIME DP - Unbound Medicine ER -