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The efficacy of Tung's acupuncture for sex hormones in polycystic ovary syndrome: A randomized controlled trial.
Complement Ther Med. 2019 Jun; 44:182-188.CT

Abstract

BACKGROUND

Polycystic ovary syndrome (PCOS) is a common and heterogeneous endocrine disorder in reproductive-age women. Tung's acupuncture, a Traditional Chinese Medicine (TCM) treatment, is widely used for PCOS in East Asia, but evidence on its efficacy is rare. The aim of this RCT study was to examine whether the Tung's acupuncture could be a complementary treatment method for PCOS.

METHODS

A total of 60 PCOS patients were randomly assigned to a Tung's acupuncture group (n = 30) or a cyproterone acetate/ethinylestradiol (CPA/EE) group (n = 30). Each participant received treatments for 12 weeks to assess the short-term treatment efficacy and then followed up for another 12 weeks to assess the long-term treatment efficacy. The primary outcome examined was change in the ratio of luteinizing hormone (LH) to follicle-stimulating hormone (FSH); the secondary outcomes examined were changes in body mass index (BMI), LH, FSH, total testosterone (TT), ovarian volume, polycystic ovary number and menstrual frequency.

RESULTS

Both groups showed significant reductions in the LH/FSH ratio, LH and TT after 12-week treatment (p < 0.001) and 12-week follow-up (p < 0.05). No significant differences existed between the two groups (p > 0.05). Both groups showed significant improvement in BMI, menstrual frequency and polycystic ovary number after 12-week treatment (p < 0.05).

CONCLUSION

Compared with CPA/EE, Tung's acupuncture showed no better improvement on LH/FSH ratio for PCOS although it could reduce the ratio. Tung's acupuncture might have some effect on long-term weight control and menstruation frequency. Further studies addressing this study's limitations are recommended.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Cao Y
Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Beijing, China.
Chen H
School of Public Health, Peking University, Beijing, China.
Zhao D
Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Beijing, China.
Zhang L
Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Beijing, China.
Yu X
Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Beijing, China.
Zhou X
The 307th Hospital of Military Chinese People's Liberation Army, Beijing, China.
Liu Z
Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. Electronic address: liuzhishun@aliyun.com.

MeSH

AcupunctureAcupuncture TherapyAdultBody Mass IndexCyproterone AcetateDrug CombinationsEthinyl EstradiolFemaleGonadal Steroid HormonesHumansPolycystic Ovary Syndrome

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

31126554

Citation

Cao, Yu, et al. "The Efficacy of Tung's Acupuncture for Sex Hormones in Polycystic Ovary Syndrome: a Randomized Controlled Trial." Complementary Therapies in Medicine, vol. 44, 2019, pp. 182-188.
Cao Y, Chen H, Zhao D, et al. The efficacy of Tung's acupuncture for sex hormones in polycystic ovary syndrome: A randomized controlled trial. Complement Ther Med. 2019;44:182-188.
Cao, Y., Chen, H., Zhao, D., Zhang, L., Yu, X., Zhou, X., & Liu, Z. (2019). The efficacy of Tung's acupuncture for sex hormones in polycystic ovary syndrome: A randomized controlled trial. Complementary Therapies in Medicine, 44, 182-188. https://doi.org/10.1016/j.ctim.2019.04.016
Cao Y, et al. The Efficacy of Tung's Acupuncture for Sex Hormones in Polycystic Ovary Syndrome: a Randomized Controlled Trial. Complement Ther Med. 2019;44:182-188. PubMed PMID: 31126554.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The efficacy of Tung's acupuncture for sex hormones in polycystic ovary syndrome: A randomized controlled trial. AU - Cao,Yu, AU - Chen,He, AU - Zhao,Danyang, AU - Zhang,Li, AU - Yu,Xiaogang, AU - Zhou,Xinmin, AU - Liu,Zhishun, Y1 - 2019/04/24/ PY - 2019/01/28/received PY - 2019/04/14/revised PY - 2019/04/22/accepted PY - 2019/5/26/entrez PY - 2019/5/28/pubmed PY - 2019/12/18/medline KW - Polycystic ovary syndrome (PCOS) KW - Randomized controlled trial (RCT) KW - The ratio of luteinizing hormone to follicle-stimulating hormone (LH/FSH) KW - Total testosterone (TT) KW - Tung’s acupuncture SP - 182 EP - 188 JF - Complementary therapies in medicine JO - Complement Ther Med VL - 44 N2 - BACKGROUND: Polycystic ovary syndrome (PCOS) is a common and heterogeneous endocrine disorder in reproductive-age women. Tung's acupuncture, a Traditional Chinese Medicine (TCM) treatment, is widely used for PCOS in East Asia, but evidence on its efficacy is rare. The aim of this RCT study was to examine whether the Tung's acupuncture could be a complementary treatment method for PCOS. METHODS: A total of 60 PCOS patients were randomly assigned to a Tung's acupuncture group (n = 30) or a cyproterone acetate/ethinylestradiol (CPA/EE) group (n = 30). Each participant received treatments for 12 weeks to assess the short-term treatment efficacy and then followed up for another 12 weeks to assess the long-term treatment efficacy. The primary outcome examined was change in the ratio of luteinizing hormone (LH) to follicle-stimulating hormone (FSH); the secondary outcomes examined were changes in body mass index (BMI), LH, FSH, total testosterone (TT), ovarian volume, polycystic ovary number and menstrual frequency. RESULTS: Both groups showed significant reductions in the LH/FSH ratio, LH and TT after 12-week treatment (p < 0.001) and 12-week follow-up (p < 0.05). No significant differences existed between the two groups (p > 0.05). Both groups showed significant improvement in BMI, menstrual frequency and polycystic ovary number after 12-week treatment (p < 0.05). CONCLUSION: Compared with CPA/EE, Tung's acupuncture showed no better improvement on LH/FSH ratio for PCOS although it could reduce the ratio. Tung's acupuncture might have some effect on long-term weight control and menstruation frequency. Further studies addressing this study's limitations are recommended. SN - 1873-6963 UR - https://www.unboundmedicine.com/medline/citation/31126554/The_efficacy_of_Tung's_acupuncture_for_sex_hormones_in_polycystic_ovary_syndrome:_A_randomized_controlled_trial_ DB - PRIME DP - Unbound Medicine ER -