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Natural Products for the Treatment of Neurodegenerative Diseases.
Curr Med Chem. 2020; 27(34):5790-5828.CM

Abstract

Neurodegenerative diseases are a heterogeneous group of disorders characterized by the progressive degeneration of the structure and function of the central nervous system or peripheral nervous system. Alzheimer's Disease (AD), Parkinson's Disease (PD) and Spinal Cord Injury (SCI) are the common neurodegenerative diseases, which typically occur in people over the age of 60. With the rapid development of an aged society, over 60 million people worldwide are suffering from these uncurable diseases. Therefore, the search for new drugs and therapeutic methods has become an increasingly important research topic. Natural products especially those from the Traditional Chinese Medicines (TCMs), are the most important sources of drugs, and have received extensive interest among pharmacist. In this review, in order to facilitate further chemical modification of those useful natural products by pharmacists, we will bring together recent studies in single natural compound from TCMs with neuroprotective effect.

Authors+Show Affiliations

Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi Guizhou 563003, China. Generic Drug Research Center of Guizhou Province, School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, 563003, P.R. China.Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi Guizhou 563003, China. Generic Drug Research Center of Guizhou Province, School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, 563003, P.R. China.Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi Guizhou 563003, China.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

31131744

Citation

Wang, Ze, et al. "Natural Products for the Treatment of Neurodegenerative Diseases." Current Medicinal Chemistry, vol. 27, no. 34, 2020, pp. 5790-5828.
Wang Z, He C, Shi JS. Natural Products for the Treatment of Neurodegenerative Diseases. Curr Med Chem. 2020;27(34):5790-5828.
Wang, Z., He, C., & Shi, J. S. (2020). Natural Products for the Treatment of Neurodegenerative Diseases. Current Medicinal Chemistry, 27(34), 5790-5828. https://doi.org/10.2174/0929867326666190527120614
Wang Z, He C, Shi JS. Natural Products for the Treatment of Neurodegenerative Diseases. Curr Med Chem. 2020;27(34):5790-5828. PubMed PMID: 31131744.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Natural Products for the Treatment of Neurodegenerative Diseases. AU - Wang,Ze, AU - He,Chunyang, AU - Shi,Jing-Shan, PY - 2019/01/28/received PY - 2019/05/06/revised PY - 2019/05/09/accepted PY - 2019/5/28/pubmed PY - 2020/12/15/medline PY - 2019/5/28/entrez KW - Alzheimer's disease KW - CDM KW - Natural Products KW - Neurodegenerative diseases KW - Parkinson's disease KW - Spinal Cord Injury SP - 5790 EP - 5828 JF - Current medicinal chemistry JO - Curr Med Chem VL - 27 IS - 34 N2 - Neurodegenerative diseases are a heterogeneous group of disorders characterized by the progressive degeneration of the structure and function of the central nervous system or peripheral nervous system. Alzheimer's Disease (AD), Parkinson's Disease (PD) and Spinal Cord Injury (SCI) are the common neurodegenerative diseases, which typically occur in people over the age of 60. With the rapid development of an aged society, over 60 million people worldwide are suffering from these uncurable diseases. Therefore, the search for new drugs and therapeutic methods has become an increasingly important research topic. Natural products especially those from the Traditional Chinese Medicines (TCMs), are the most important sources of drugs, and have received extensive interest among pharmacist. In this review, in order to facilitate further chemical modification of those useful natural products by pharmacists, we will bring together recent studies in single natural compound from TCMs with neuroprotective effect. SN - 1875-533X UR - https://www.unboundmedicine.com/medline/citation/31131744/Natural_Products_for_the_Treatment_of_Neurodegenerative_Diseases_ DB - PRIME DP - Unbound Medicine ER -