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Screening of pharmacological uses of Urtica dioica and others benefits.
Prog Biophys Mol Biol. 2020 01; 150:67-77.PB

Abstract

BACKGROUND

Natural products, whether pure compounds or standardized plant extracts, offer unlimited opportunities for other drug sources due to the unequaled availability of chemical diversity. Stinging Nettle (Urtica dioica) is a unique herbaceous perennial flowering plant with stinging hairs. The leaf extract of nettle was one of the herbal remedies which the experimental, clinical and trials have complemented each other. It is a very well-known plant with a wide historical background use of stems, leaves and roots. It has a long history of use as power sources such as soup or curry, and also used as fiber and a medicinal plant. Urtica dioica has traditionally been used in the control of cardiovascular disorders especially hypertension. The leaf extract of Urtica dioica has been reported to improve glucose homeostasis in vivo. Nettle root could prevent some of the effects of prostatic hyperplasia. Extracts of nettle leaf are used as anti-inflammatory remedies for rheumatoid arthritis. Urtica dioica extract significantly increased the sensitivity of breast cancer cells to paclitaxel. This article aims to review the very wide ranging of pharmacological effects of Urtica dioica extract.

METHODS

Articles on PuBmed between 1980 and 2019.

RESULTS

Description and critical review of the pharmacological effects of Urtica dioica and other uses.

CONCLUSION

The nettle is actually a plant with many qualities and uses. The interest in it is deserved and it is given by other studies and investigations.

Authors+Show Affiliations

Laboratory of Pharmacology, Faculty of Medicine of Sfax - University of Sfax, Tunisia.Laboratory of Pharmacology, Faculty of Medicine of Sfax - University of Sfax, Tunisia. Electronic address: affeshanen13@yahoo.fr.Laboratory of Pharmacology, Faculty of Medicine of Sfax - University of Sfax, Tunisia.Laboratory of Pharmacology, Faculty of Medicine of Sfax - University of Sfax, Tunisia.Laboratory of Pharmacology, Faculty of Medicine of Sfax - University of Sfax, Tunisia.Laboratory of Pharmacology, Faculty of Medicine of Sfax - University of Sfax, Tunisia.Laboratory of Pharmacology, Faculty of Medicine of Sfax - University of Sfax, Tunisia.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

31163183

Citation

Dhouibi, Raouia, et al. "Screening of Pharmacological Uses of Urtica Dioica and Others Benefits." Progress in Biophysics and Molecular Biology, vol. 150, 2020, pp. 67-77.
Dhouibi R, Affes H, Ben Salem M, et al. Screening of pharmacological uses of Urtica dioica and others benefits. Prog Biophys Mol Biol. 2020;150:67-77.
Dhouibi, R., Affes, H., Ben Salem, M., Hammami, S., Sahnoun, Z., Zeghal, K. M., & Ksouda, K. (2020). Screening of pharmacological uses of Urtica dioica and others benefits. Progress in Biophysics and Molecular Biology, 150, 67-77. https://doi.org/10.1016/j.pbiomolbio.2019.05.008
Dhouibi R, et al. Screening of Pharmacological Uses of Urtica Dioica and Others Benefits. Prog Biophys Mol Biol. 2020;150:67-77. PubMed PMID: 31163183.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Screening of pharmacological uses of Urtica dioica and others benefits. AU - Dhouibi,Raouia, AU - Affes,Hanen, AU - Ben Salem,Maryem, AU - Hammami,Serria, AU - Sahnoun,Zouheir, AU - Zeghal,Khaled Mounir, AU - Ksouda,Kamilia, Y1 - 2019/06/01/ PY - 2019/05/03/received PY - 2019/05/22/revised PY - 2019/05/29/accepted PY - 2019/6/5/pubmed PY - 2020/12/18/medline PY - 2019/6/5/entrez KW - Antioxidant KW - Cancer KW - Cardiovascular KW - Pharmacological effects KW - Urtica dioica KW - nettle SP - 67 EP - 77 JF - Progress in biophysics and molecular biology JO - Prog Biophys Mol Biol VL - 150 N2 - BACKGROUND: Natural products, whether pure compounds or standardized plant extracts, offer unlimited opportunities for other drug sources due to the unequaled availability of chemical diversity. Stinging Nettle (Urtica dioica) is a unique herbaceous perennial flowering plant with stinging hairs. The leaf extract of nettle was one of the herbal remedies which the experimental, clinical and trials have complemented each other. It is a very well-known plant with a wide historical background use of stems, leaves and roots. It has a long history of use as power sources such as soup or curry, and also used as fiber and a medicinal plant. Urtica dioica has traditionally been used in the control of cardiovascular disorders especially hypertension. The leaf extract of Urtica dioica has been reported to improve glucose homeostasis in vivo. Nettle root could prevent some of the effects of prostatic hyperplasia. Extracts of nettle leaf are used as anti-inflammatory remedies for rheumatoid arthritis. Urtica dioica extract significantly increased the sensitivity of breast cancer cells to paclitaxel. This article aims to review the very wide ranging of pharmacological effects of Urtica dioica extract. METHODS: Articles on PuBmed between 1980 and 2019. RESULTS: Description and critical review of the pharmacological effects of Urtica dioica and other uses. CONCLUSION: The nettle is actually a plant with many qualities and uses. The interest in it is deserved and it is given by other studies and investigations. SN - 1873-1732 UR - https://www.unboundmedicine.com/medline/citation/31163183/Screening_of_pharmacological_uses_of_Urtica_dioica_and_others_benefits_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0079-6107(19)30098-7 DB - PRIME DP - Unbound Medicine ER -