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Spatial and Temporal Characteristics of Visual Field Progression in Glaucoma Assessed by Parallel Factor Analysis.
Korean J Ophthalmol 2019; 33(3):279-286KJ

Abstract

PURPOSE

To explore spatial and temporal characteristics of glaucomatous visual field (VF) progression through multi-way decomposition of data.

METHODS

Six serial VF exams with intervals of 6.0 ± 1.0 months in 121 pre-perimetric glaucoma eyes and 80 perimetric glaucoma eyes were arranged into a three-dimensional cube. The data were decomposed using parallel factor analysis.

RESULTS

Three tri-linear components (i.e., spatial scores, temporal loadings, and subject-specific loadings) were identified. Component 1 clearly showed differences between superior and inferior hemispheres, linear trends over time, and wide variability in perimetric glaucoma. Findings were compatible with well-known characteristics of glaucomatous VF defects. Component 2 showed nasal and central areas in contrast with superior, inferior, and temporal peripheral locations, whereas component 3 showed a contrast between nasal and temporal hemispheres. Both components 2 and 3 failed to show clear temporal trends.

CONCLUSIONS

Identification of spatio-temporal patterns shows new possibilities for a multi-way decomposition methodology for earlier diagnosis and prediction of glaucomatous VF progression.

Authors+Show Affiliations

Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. sungeye@gmail.com.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31179660

Citation

Kim, Seungmo, et al. "Spatial and Temporal Characteristics of Visual Field Progression in Glaucoma Assessed By Parallel Factor Analysis." Korean Journal of Ophthalmology : KJO, vol. 33, no. 3, 2019, pp. 279-286.
Kim S, Shon K, Sung KR. Spatial and Temporal Characteristics of Visual Field Progression in Glaucoma Assessed by Parallel Factor Analysis. Korean J Ophthalmol. 2019;33(3):279-286.
Kim, S., Shon, K., & Sung, K. R. (2019). Spatial and Temporal Characteristics of Visual Field Progression in Glaucoma Assessed by Parallel Factor Analysis. Korean Journal of Ophthalmology : KJO, 33(3), pp. 279-286. doi:10.3341/kjo.2019.0004.
Kim S, Shon K, Sung KR. Spatial and Temporal Characteristics of Visual Field Progression in Glaucoma Assessed By Parallel Factor Analysis. Korean J Ophthalmol. 2019;33(3):279-286. PubMed PMID: 31179660.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Spatial and Temporal Characteristics of Visual Field Progression in Glaucoma Assessed by Parallel Factor Analysis. AU - Kim,Seungmo, AU - Shon,Kilhwan, AU - Sung,Kyung Rim, PY - 2019/02/06/received PY - 2019/02/22/revised PY - 2019/02/27/accepted PY - 2019/6/11/entrez PY - 2019/6/11/pubmed PY - 2019/7/31/medline KW - Glaucoma KW - Multi-way decomposition KW - Parallel factor analysis KW - Visual fields SP - 279 EP - 286 JF - Korean journal of ophthalmology : KJO JO - Korean J Ophthalmol VL - 33 IS - 3 N2 - PURPOSE: To explore spatial and temporal characteristics of glaucomatous visual field (VF) progression through multi-way decomposition of data. METHODS: Six serial VF exams with intervals of 6.0 ± 1.0 months in 121 pre-perimetric glaucoma eyes and 80 perimetric glaucoma eyes were arranged into a three-dimensional cube. The data were decomposed using parallel factor analysis. RESULTS: Three tri-linear components (i.e., spatial scores, temporal loadings, and subject-specific loadings) were identified. Component 1 clearly showed differences between superior and inferior hemispheres, linear trends over time, and wide variability in perimetric glaucoma. Findings were compatible with well-known characteristics of glaucomatous VF defects. Component 2 showed nasal and central areas in contrast with superior, inferior, and temporal peripheral locations, whereas component 3 showed a contrast between nasal and temporal hemispheres. Both components 2 and 3 failed to show clear temporal trends. CONCLUSIONS: Identification of spatio-temporal patterns shows new possibilities for a multi-way decomposition methodology for earlier diagnosis and prediction of glaucomatous VF progression. SN - 2092-9382 UR - https://www.unboundmedicine.com/medline/citation/31179660/Spatial_and_Temporal_Characteristics_of_Visual_Field_Progression_in_Glaucoma_Assessed_by_Parallel_Factor_Analysis L2 - https://ekjo.org/DOIx.php?id=10.3341/kjo.2019.0004 DB - PRIME DP - Unbound Medicine ER -