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"For Mass Eye and Ear Special Issue" Adaptive Optics in the Evaluation of Diabetic Retinopathy.
Semin Ophthalmol 2019; 34(4):189-197SO

Abstract

Retinal imaging is a fundamental tool for clinical and research efforts in the evaluation and management of diabetic retinopathy. Adaptive optics (AO) is an imaging technique that enables correction of over 90% of the optical aberrations of an individual eye induced primarily by the tear film, cornea and lens. The two major tasks of any AO system are to measure the optical imperfections of the eye and to then compensate for these aberrations to generate a corrected wavefront of reflected light from the eye. AO scanning laser ophthalmoscopy (AOSLO) provides a theoretical lateral resolution limit of 1.4 μm, allowing the study of microscopic features of the retinal vascular and neural tissue. AOSLO studies have revealed irregularities of the photoreceptor mosaic, vascular loss, and details of vascular lesions in diabetic eyes that may provide new insight into development, regression, and response to therapy of diabetic eye disease.

Authors+Show Affiliations

a Beetham Eye Institute , Joslin Diabetes Center , Boston , MA , USA. b Department of Ophthalmology , Harvard Medical School , Boston , MA , USA.a Beetham Eye Institute , Joslin Diabetes Center , Boston , MA , USA. b Department of Ophthalmology , Harvard Medical School , Boston , MA , USA.a Beetham Eye Institute , Joslin Diabetes Center , Boston , MA , USA. c Department of Medicine , Harvard Medical School , Boston , MA , USA.a Beetham Eye Institute , Joslin Diabetes Center , Boston , MA , USA. b Department of Ophthalmology , Harvard Medical School , Boston , MA , USA.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

31188056

Citation

AbdelAl, Omar, et al. ""For Mass Eye and Ear Special Issue" Adaptive Optics in the Evaluation of Diabetic Retinopathy." Seminars in Ophthalmology, vol. 34, no. 4, 2019, pp. 189-197.
AbdelAl O, Ashraf M, Sampani K, et al. "For Mass Eye and Ear Special Issue" Adaptive Optics in the Evaluation of Diabetic Retinopathy. Semin Ophthalmol. 2019;34(4):189-197.
AbdelAl, O., Ashraf, M., Sampani, K., & Sun, J. K. (2019). "For Mass Eye and Ear Special Issue" Adaptive Optics in the Evaluation of Diabetic Retinopathy. Seminars in Ophthalmology, 34(4), pp. 189-197. doi:10.1080/08820538.2019.1620794.
AbdelAl O, et al. "For Mass Eye and Ear Special Issue" Adaptive Optics in the Evaluation of Diabetic Retinopathy. Semin Ophthalmol. 2019;34(4):189-197. PubMed PMID: 31188056.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - "For Mass Eye and Ear Special Issue" Adaptive Optics in the Evaluation of Diabetic Retinopathy. AU - AbdelAl,Omar, AU - Ashraf,Mohammed, AU - Sampani,Konstantina, AU - Sun,Jennifer K, Y1 - 2019/06/12/ PY - 2019/6/13/pubmed PY - 2019/7/20/medline PY - 2019/6/13/entrez KW - Adaptive optics KW - diabetes mellitus KW - diabetic macular edema KW - diabetic retinopathy KW - scanning laser ophthalmoscopy SP - 189 EP - 197 JF - Seminars in ophthalmology JO - Semin Ophthalmol VL - 34 IS - 4 N2 - Retinal imaging is a fundamental tool for clinical and research efforts in the evaluation and management of diabetic retinopathy. Adaptive optics (AO) is an imaging technique that enables correction of over 90% of the optical aberrations of an individual eye induced primarily by the tear film, cornea and lens. The two major tasks of any AO system are to measure the optical imperfections of the eye and to then compensate for these aberrations to generate a corrected wavefront of reflected light from the eye. AO scanning laser ophthalmoscopy (AOSLO) provides a theoretical lateral resolution limit of 1.4 μm, allowing the study of microscopic features of the retinal vascular and neural tissue. AOSLO studies have revealed irregularities of the photoreceptor mosaic, vascular loss, and details of vascular lesions in diabetic eyes that may provide new insight into development, regression, and response to therapy of diabetic eye disease. SN - 1744-5205 UR - https://www.unboundmedicine.com/medline/citation/31188056/"For_Mass_Eye_and_Ear_Special_Issue"_Adaptive_Optics_in_the_Evaluation_of_Diabetic_Retinopathy L2 - http://www.tandfonline.com/doi/full/10.1080/08820538.2019.1620794 DB - PRIME DP - Unbound Medicine ER -