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[Measurement of intestinal permeability to sugars: application in the diagnosis of celiac disease and cow's milk protein enteropathy].
Pathol Biol (Paris). 1987 Oct; 35(8):1179-82.PB

Abstract

Intestinal permeability to macromolecules was studied by measuring differential urinary elimination of two orally ingested non-metabolizable sugars of different molecular size, mannitol and lactulose. In 25 control children, mannitol and lactulose urinary elimination were 16.30 +/- 5.77% and 0.33 +/- 0.10% of ingested dose, respectively, with a mean lactulose/mannitol (M/M) urinary ratio of 2.73 +/- 0.70%. In 7 celiac children, L/M ratio exhibited a significant rise: 8.53 +/- 2.54% (p less than 0.001). In 7 children with cow's milk sensitive enteropathy under exclusion diet, L/M ratio was normal in fasting condition: 2.63 +/- 1.28% and raised significantly during provocation test with milk: 7.22 +/- 3.88% (p less than 0.01). Intestinal permeability test is a reliable index of villous atrophy and cow's milk sensitive enteropathy.

Authors+Show Affiliations

Fondation de Recherche en Hormonologie, Fresnes, France.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

fre

PubMed ID

3120136

Citation

Dupont, C, et al. "[Measurement of Intestinal Permeability to Sugars: Application in the Diagnosis of Celiac Disease and Cow's Milk Protein Enteropathy]." Pathologie-biologie, vol. 35, no. 8, 1987, pp. 1179-82.
Dupont C, Barau E, Dehennin L, et al. [Measurement of intestinal permeability to sugars: application in the diagnosis of celiac disease and cow's milk protein enteropathy]. Pathol Biol. 1987;35(8):1179-82.
Dupont, C., Barau, E., Dehennin, L., & Molkhou, P. (1987). [Measurement of intestinal permeability to sugars: application in the diagnosis of celiac disease and cow's milk protein enteropathy]. Pathologie-biologie, 35(8), 1179-82.
Dupont C, et al. [Measurement of Intestinal Permeability to Sugars: Application in the Diagnosis of Celiac Disease and Cow's Milk Protein Enteropathy]. Pathol Biol. 1987;35(8):1179-82. PubMed PMID: 3120136.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Measurement of intestinal permeability to sugars: application in the diagnosis of celiac disease and cow's milk protein enteropathy]. AU - Dupont,C, AU - Barau,E, AU - Dehennin,L, AU - Molkhou,P, PY - 1987/10/1/pubmed PY - 1987/10/1/medline PY - 1987/10/1/entrez SP - 1179 EP - 82 JF - Pathologie-biologie JO - Pathol. Biol. VL - 35 IS - 8 N2 - Intestinal permeability to macromolecules was studied by measuring differential urinary elimination of two orally ingested non-metabolizable sugars of different molecular size, mannitol and lactulose. In 25 control children, mannitol and lactulose urinary elimination were 16.30 +/- 5.77% and 0.33 +/- 0.10% of ingested dose, respectively, with a mean lactulose/mannitol (M/M) urinary ratio of 2.73 +/- 0.70%. In 7 celiac children, L/M ratio exhibited a significant rise: 8.53 +/- 2.54% (p less than 0.001). In 7 children with cow's milk sensitive enteropathy under exclusion diet, L/M ratio was normal in fasting condition: 2.63 +/- 1.28% and raised significantly during provocation test with milk: 7.22 +/- 3.88% (p less than 0.01). Intestinal permeability test is a reliable index of villous atrophy and cow's milk sensitive enteropathy. SN - 0369-8114 UR - https://www.unboundmedicine.com/medline/citation/3120136/[Measurement_of_intestinal_permeability_to_sugars:_application_in_the_diagnosis_of_celiac_disease_and_cow's_milk_protein_enteropathy]_ L2 - http://www.diseaseinfosearch.org/result/1186 DB - PRIME DP - Unbound Medicine ER -