Tags

Type your tag names separated by a space and hit enter

An overview on role of some trace elements in human reproductive health, sperm function and fertilization process.

Abstract

Human semen contains several trace elements such as calcium (Ca), copper (Cu), manganese (Mn), magnesium (Mg), zinc (Zn) and selenium (Se) which are necessary for reproductive health, normal spermatogenesis, sperm maturation, motility and capacitation, as well as normal sperm function. In this review, the potential role of these trace elements in male reproductive health, normal function of spermatozoa and fertility potency were considered. We selected and reviewed articles that considered crucial roles of trace elements in human sperm function and fertility. Ca is essential for sperm motility and its hyperactivation, sperm capacitation and acrosome reaction, as well as sperm chemotaxis. Sodium (Na) and potassium (K) are involved in sperm motility and capacitation. Mg is necessary for normal ejaculation, spermatogenesis and sperm motility. Zn is one of the most significant nutrients in human semen. Seminal deficiency of Zn can be associated with delayed testicular development, impaired spermatogenesis, deficiency of sex hormones, oxidative stress and inflammation, and apoptosis. Se is another significant element which has antioxidative properties and is essential for spermatogenesis and the maintenance of male fertility. Mn is a potent stimulator for sperm motility; however, increased level of seminal plasma Se can be toxic for sperm. Like Se, Cu has antioxidative properties and has a positive effect on sperm parameters. Decreased level of these trace elements can negatively affect human reproductive health, semen quality, sperm normal function and as the result, fertility potency in men. Measurement of these trace elements in men with idiopathic infertility is necessary.

Authors+Show Affiliations

Department of Medical Radiation Engineering, Central Tehran Branch, Islamic Azad University, Tehran, Iran.Department of Medical Radiation Engineering, Central Tehran Branch, Islamic Azad University, Tehran, Iran.Laboratory of Regenerative Medicine and Biomedical Innovations, Pasteur Institute of Iran, Tehran, Iran.University Scientific Education and Research Network, Tehran, Iran.Department of Medical Genetics, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, P.O. Box: 19945-581, Tehran, Iran.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

31203261

Citation

Mirnamniha, Mahdiyeh, et al. "An Overview On Role of some Trace Elements in Human Reproductive Health, Sperm Function and Fertilization Process." Reviews On Environmental Health, 2019.
Mirnamniha M, Faroughi F, Tahmasbpour E, et al. An overview on role of some trace elements in human reproductive health, sperm function and fertilization process. Rev Environ Health. 2019.
Mirnamniha, M., Faroughi, F., Tahmasbpour, E., Ebrahimi, P., & Beigi Harchegani, A. (2019). An overview on role of some trace elements in human reproductive health, sperm function and fertilization process. Reviews On Environmental Health, doi:10.1515/reveh-2019-0008.
Mirnamniha M, et al. An Overview On Role of some Trace Elements in Human Reproductive Health, Sperm Function and Fertilization Process. Rev Environ Health. 2019 Jun 14; PubMed PMID: 31203261.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An overview on role of some trace elements in human reproductive health, sperm function and fertilization process. AU - Mirnamniha,Mahdiyeh, AU - Faroughi,Fereshteh, AU - Tahmasbpour,Eisa, AU - Ebrahimi,Pirooz, AU - Beigi Harchegani,Asghar, Y1 - 2019/06/14/ PY - 2019/02/04/received PY - 2019/04/28/accepted PY - 2019/6/17/pubmed PY - 2019/6/17/medline PY - 2019/6/17/entrez KW - male infertility KW - reproductive health KW - sperm KW - spermatogenesis KW - trace elements JF - Reviews on environmental health JO - Rev Environ Health N2 - Human semen contains several trace elements such as calcium (Ca), copper (Cu), manganese (Mn), magnesium (Mg), zinc (Zn) and selenium (Se) which are necessary for reproductive health, normal spermatogenesis, sperm maturation, motility and capacitation, as well as normal sperm function. In this review, the potential role of these trace elements in male reproductive health, normal function of spermatozoa and fertility potency were considered. We selected and reviewed articles that considered crucial roles of trace elements in human sperm function and fertility. Ca is essential for sperm motility and its hyperactivation, sperm capacitation and acrosome reaction, as well as sperm chemotaxis. Sodium (Na) and potassium (K) are involved in sperm motility and capacitation. Mg is necessary for normal ejaculation, spermatogenesis and sperm motility. Zn is one of the most significant nutrients in human semen. Seminal deficiency of Zn can be associated with delayed testicular development, impaired spermatogenesis, deficiency of sex hormones, oxidative stress and inflammation, and apoptosis. Se is another significant element which has antioxidative properties and is essential for spermatogenesis and the maintenance of male fertility. Mn is a potent stimulator for sperm motility; however, increased level of seminal plasma Se can be toxic for sperm. Like Se, Cu has antioxidative properties and has a positive effect on sperm parameters. Decreased level of these trace elements can negatively affect human reproductive health, semen quality, sperm normal function and as the result, fertility potency in men. Measurement of these trace elements in men with idiopathic infertility is necessary. SN - 2191-0308 UR - https://www.unboundmedicine.com/medline/citation/31203261/An_overview_on_role_of_some_trace_elements_in_human_reproductive_health,_sperm_function_and_fertilization_process L2 - https://www.degruyter.com/doi/10.1515/reveh-2019-0008 DB - PRIME DP - Unbound Medicine ER -