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Prospective, multi-centric benchmark study assessing delirium: prevalence, incidence and its correlates in hospitalized elderly Lebanese patients.

Abstract

BACKGROUND

With the increase in the proportion of elderly Lebanese patients, little is known about delirium's prevalence, incidence and correlated factors.

AIMS

To identify the prevalence, incidence and factors associated with overall and incident delirium in hospitalized elderly Lebanese patients.

METHODS

A convenient sample was recruited from three university hospitals affiliated to the Lebanese university faculty of medical sciences. We included patients aged more than 65 years. Baseline factors were examined upon presentation and the confusion assessment method (CAM) was used to detect prevalent delirium upon admission or within the first 48 h. Enrolled patients were then assessed every other day to detect incident delirium cases.

RESULTS

Among the 230 patients included, delirium prevalence was 17% and incidence 8.7%. We found that a history of falls (odds ratio (OR) = 5.12; p = 0.001), immobilization (OR = 7.33; p = 0.035), polypharmacy (OR = 5.07; p = 0.026) along with tachycardia (OR = 6.94; p = 0.03) and severe anemia (OR = 12.5; p = 0.005) upon admission were significant factors associated with overall delirium (incident and prevalent delirium cases). Whereas, living alone was significantly associated with lower odds for overall delirium (OR = 0.03; p = 0.02). Moreover, current smoking (OR = 14; p = 0.02), low oxygen saturation (OR = 9.6; p = 0.008) and severe anemia (OR = 8.4; p = 0.013) upon admission remained significantly associated with higher odds for incident delirium along with urine catheter placement (OR = 7.8; p = 0.015).

CONCLUSION

Secondary to the burden of delirium and its impact on mortality among elderly population, trying to understand and adjust modifiable factors would promote more appropriate prevention strategies.

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  • Authors+Show Affiliations

    ,

    Psychiatry Department, Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon. carmenzrour@hotmail.com. , Boulevard de Smet de Naeyer 414, Jette 1090, Brussels, Belgium. carmenzrour@hotmail.com.

    ,

    Psychiatry Department, Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon.

    ,

    Family Medicine Department, Faculty of Medical Sciences, Saint Joseph University, Beirut, Lebanon.

    ,

    Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon.

    ,

    Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon.

    Psychiatry Department, Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon.

    Source

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    31203529

    Citation

    Zrour, Carmen, et al. "Prospective, Multi-centric Benchmark Study Assessing Delirium: Prevalence, Incidence and Its Correlates in Hospitalized Elderly Lebanese Patients." Aging Clinical and Experimental Research, 2019.
    Zrour C, Haddad R, Zoghbi M, et al. Prospective, multi-centric benchmark study assessing delirium: prevalence, incidence and its correlates in hospitalized elderly Lebanese patients. Aging Clin Exp Res. 2019.
    Zrour, C., Haddad, R., Zoghbi, M., Kharsa, Z., Hijazi, M., & Naja, W. (2019). Prospective, multi-centric benchmark study assessing delirium: prevalence, incidence and its correlates in hospitalized elderly Lebanese patients. Aging Clinical and Experimental Research, doi:10.1007/s40520-019-01242-2.
    Zrour C, et al. Prospective, Multi-centric Benchmark Study Assessing Delirium: Prevalence, Incidence and Its Correlates in Hospitalized Elderly Lebanese Patients. Aging Clin Exp Res. 2019 Jun 15; PubMed PMID: 31203529.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Prospective, multi-centric benchmark study assessing delirium: prevalence, incidence and its correlates in hospitalized elderly Lebanese patients. AU - Zrour,Carmen, AU - Haddad,Ramzi, AU - Zoghbi,Marouan, AU - Kharsa,Zahraa, AU - Hijazi,Mariam, AU - Naja,Wadih, Y1 - 2019/06/15/ PY - 2019/03/29/received PY - 2019/06/05/accepted PY - 2019/6/17/entrez PY - 2019/6/17/pubmed PY - 2019/6/17/medline KW - Correlated factors KW - Delirium KW - Hospitalized elderly patients KW - Incidence KW - Overall prevalence JF - Aging clinical and experimental research JO - Aging Clin Exp Res N2 - BACKGROUND: With the increase in the proportion of elderly Lebanese patients, little is known about delirium's prevalence, incidence and correlated factors. AIMS: To identify the prevalence, incidence and factors associated with overall and incident delirium in hospitalized elderly Lebanese patients. METHODS: A convenient sample was recruited from three university hospitals affiliated to the Lebanese university faculty of medical sciences. We included patients aged more than 65 years. Baseline factors were examined upon presentation and the confusion assessment method (CAM) was used to detect prevalent delirium upon admission or within the first 48 h. Enrolled patients were then assessed every other day to detect incident delirium cases. RESULTS: Among the 230 patients included, delirium prevalence was 17% and incidence 8.7%. We found that a history of falls (odds ratio (OR) = 5.12; p = 0.001), immobilization (OR = 7.33; p = 0.035), polypharmacy (OR = 5.07; p = 0.026) along with tachycardia (OR = 6.94; p = 0.03) and severe anemia (OR = 12.5; p = 0.005) upon admission were significant factors associated with overall delirium (incident and prevalent delirium cases). Whereas, living alone was significantly associated with lower odds for overall delirium (OR = 0.03; p = 0.02). Moreover, current smoking (OR = 14; p = 0.02), low oxygen saturation (OR = 9.6; p = 0.008) and severe anemia (OR = 8.4; p = 0.013) upon admission remained significantly associated with higher odds for incident delirium along with urine catheter placement (OR = 7.8; p = 0.015). CONCLUSION: Secondary to the burden of delirium and its impact on mortality among elderly population, trying to understand and adjust modifiable factors would promote more appropriate prevention strategies. SN - 1720-8319 UR - https://www.unboundmedicine.com/medline/citation/31203529/Prospective,_multi-centric_benchmark_study_assessing_delirium:_prevalence,_incidence_and_its_correlates_in_hospitalized_elderly_Lebanese_patients L2 - https://dx.doi.org/10.1007/s40520-019-01242-2 DB - PRIME DP - Unbound Medicine ER -