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Update on human African trypanosomiasis (sleeping sickness).
J Neurol. 2019 Sep; 266(9):2334-2337.JN

Abstract

Human African trypanosomiasis (HAT), also known as sleeping sickness, is one of the Africa's 'neglected diseases' and is caused by infection with protozoan parasites of the Trypanosoma genus. Transmitted by the bite of the tsetse fly, it puts 70 million people at risk throughout sub-Saharan Africa and is usually fatal if untreated or inadequately treated. In this brief overview, some important recent developments in this disease are outlined. These cover various aspects including a reduction in disease incidence, newly recognised parasite reservoir sites in humans, disease outcome, novel diagnostic methods, new and improved treatment, and disease neuropathogenesis.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Kennedy PGE
Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Garscube Campus, Glasgow, G61 1QH, Scotland, UK. Peter.Kennedy@glasgow.ac.uk.

MeSH

AnimalsBenzamidesBoron CompoundsHumansNeglected DiseasesTrypanosoma brucei gambienseTrypanosoma brucei rhodesienseTrypanosomiasis, African

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

31209574

Citation

Kennedy, Peter G E.. "Update On Human African Trypanosomiasis (sleeping Sickness)." Journal of Neurology, vol. 266, no. 9, 2019, pp. 2334-2337.
Kennedy PGE. Update on human African trypanosomiasis (sleeping sickness). J Neurol. 2019;266(9):2334-2337.
Kennedy, P. G. E. (2019). Update on human African trypanosomiasis (sleeping sickness). Journal of Neurology, 266(9), 2334-2337. https://doi.org/10.1007/s00415-019-09425-7
Kennedy PGE. Update On Human African Trypanosomiasis (sleeping Sickness). J Neurol. 2019;266(9):2334-2337. PubMed PMID: 31209574.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Update on human African trypanosomiasis (sleeping sickness). A1 - Kennedy,Peter G E, Y1 - 2019/06/17/ PY - 2019/05/28/received PY - 2019/06/06/accepted PY - 2019/6/19/pubmed PY - 2020/1/29/medline PY - 2019/6/19/entrez KW - CNS KW - Diagnostic staging KW - Human African trypanosomiasis KW - Parasite KW - Sleeping sickness KW - Sub-Saharan Africa KW - Tsetse fly SP - 2334 EP - 2337 JF - Journal of neurology JO - J Neurol VL - 266 IS - 9 N2 - Human African trypanosomiasis (HAT), also known as sleeping sickness, is one of the Africa's 'neglected diseases' and is caused by infection with protozoan parasites of the Trypanosoma genus. Transmitted by the bite of the tsetse fly, it puts 70 million people at risk throughout sub-Saharan Africa and is usually fatal if untreated or inadequately treated. In this brief overview, some important recent developments in this disease are outlined. These cover various aspects including a reduction in disease incidence, newly recognised parasite reservoir sites in humans, disease outcome, novel diagnostic methods, new and improved treatment, and disease neuropathogenesis. SN - 1432-1459 UR - https://www.unboundmedicine.com/medline/citation/31209574/Update_on_human_African_trypanosomiasis__sleeping_sickness__ DB - PRIME DP - Unbound Medicine ER -