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[Cytometric study of the effects of destruxin E on leukemic cells in mice].
C R Acad Sci III. 1987; 305(14):575-8.CR

Abstract

The activity of destruxin E, a cryptogamic toxin isolated from the hyphomycete Metarhizium anisopliae, was studied on mouse leukemia cells (L 1210 and P 388) in culture. Besides a cytotoxic effect, a cytostatic effect (increase of diploïd cells proportion) was observed with all doses for P 388 (from 10 micrograms/ml to 0.001 microgram/ml) and to a concentration of 0.1 microgram/ml for L 1210. At the lower doses, the effect on cellular DNA content appears distinctly.

Authors+Show Affiliations

Laboratoire de Biologie cellulaire et d'Immunogénétique, Faculté de Médecine de Montpellier-Nîmes.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

fre

PubMed ID

3121146

Citation

Odier, F, et al. "[Cytometric Study of the Effects of Destruxin E On Leukemic Cells in Mice]." Comptes Rendus De l'Academie Des Sciences. Serie III, Sciences De La Vie, vol. 305, no. 14, 1987, pp. 575-8.
Odier F, Vago P, Quiot JM, et al. [Cytometric study of the effects of destruxin E on leukemic cells in mice]. C R Acad Sci III. 1987;305(14):575-8.
Odier, F., Vago, P., Quiot, J. M., Devauchelle, G., & Bureau, J. P. (1987). [Cytometric study of the effects of destruxin E on leukemic cells in mice]. Comptes Rendus De l'Academie Des Sciences. Serie III, Sciences De La Vie, 305(14), 575-8.
Odier F, et al. [Cytometric Study of the Effects of Destruxin E On Leukemic Cells in Mice]. C R Acad Sci III. 1987;305(14):575-8. PubMed PMID: 3121146.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Cytometric study of the effects of destruxin E on leukemic cells in mice]. AU - Odier,F, AU - Vago,P, AU - Quiot,J M, AU - Devauchelle,G, AU - Bureau,J P, PY - 1987/1/1/pubmed PY - 1987/1/1/medline PY - 1987/1/1/entrez SP - 575 EP - 8 JF - Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie JO - C R Acad Sci III VL - 305 IS - 14 N2 - The activity of destruxin E, a cryptogamic toxin isolated from the hyphomycete Metarhizium anisopliae, was studied on mouse leukemia cells (L 1210 and P 388) in culture. Besides a cytotoxic effect, a cytostatic effect (increase of diploïd cells proportion) was observed with all doses for P 388 (from 10 micrograms/ml to 0.001 microgram/ml) and to a concentration of 0.1 microgram/ml for L 1210. At the lower doses, the effect on cellular DNA content appears distinctly. SN - 0764-4469 UR - https://www.unboundmedicine.com/medline/citation/3121146/[Cytometric_study_of_the_effects_of_destruxin_E_on_leukemic_cells_in_mice]_ DB - PRIME DP - Unbound Medicine ER -