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Nutritional therapy of Crohn's disease in childhood.
Dig Dis Sci. 1987 Dec; 32(12 Suppl):82S-88S.DD

Abstract

Crohn's disease is a chronic, incurable inflammatory bowel disease commonly diagnosed in childhood and adolescence. Growth failure represents a common, serious complication unique to the pediatric age group. Although the etiology of growth failure is multifactorial, malnutrition due to inadequate nutrient intake is the primary cause. Recent studies have demonstrated that nutritional supplementation through an enteral or parenteral route restores body composition and reverses linear and ponderal growth failure. The development of elemental diets that can be administered nasogastrically at home has afforded a more practical, less expensive, and less hazardous method of providing Crohn's disease patients with nutritional supplementation and bowel rest. Elemental-diet therapy has also been shown to be a safe, effective method of inducing a remission in acute Crohn's disease. Further studies are required to develop optimal nutritional therapy which may sustain long-term remission in this disease.

Authors+Show Affiliations

Division of Gastroenterology, Hospital Sainte-Justine, Montreal, Quebec, Canada.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

3121269

Citation

Seidman, E G., et al. "Nutritional Therapy of Crohn's Disease in Childhood." Digestive Diseases and Sciences, vol. 32, no. 12 Suppl, 1987, 82S-88S.
Seidman EG, Roy CC, Weber AM, et al. Nutritional therapy of Crohn's disease in childhood. Dig Dis Sci. 1987;32(12 Suppl):82S-88S.
Seidman, E. G., Roy, C. C., Weber, A. M., & Morin, C. L. (1987). Nutritional therapy of Crohn's disease in childhood. Digestive Diseases and Sciences, 32(12 Suppl), 82S-88S.
Seidman EG, et al. Nutritional Therapy of Crohn's Disease in Childhood. Dig Dis Sci. 1987;32(12 Suppl):82S-88S. PubMed PMID: 3121269.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nutritional therapy of Crohn's disease in childhood. AU - Seidman,E G, AU - Roy,C C, AU - Weber,A M, AU - Morin,C L, PY - 1987/12/1/pubmed PY - 1987/12/1/medline PY - 1987/12/1/entrez SP - 82S EP - 88S JF - Digestive diseases and sciences JO - Dig Dis Sci VL - 32 IS - 12 Suppl N2 - Crohn's disease is a chronic, incurable inflammatory bowel disease commonly diagnosed in childhood and adolescence. Growth failure represents a common, serious complication unique to the pediatric age group. Although the etiology of growth failure is multifactorial, malnutrition due to inadequate nutrient intake is the primary cause. Recent studies have demonstrated that nutritional supplementation through an enteral or parenteral route restores body composition and reverses linear and ponderal growth failure. The development of elemental diets that can be administered nasogastrically at home has afforded a more practical, less expensive, and less hazardous method of providing Crohn's disease patients with nutritional supplementation and bowel rest. Elemental-diet therapy has also been shown to be a safe, effective method of inducing a remission in acute Crohn's disease. Further studies are required to develop optimal nutritional therapy which may sustain long-term remission in this disease. SN - 0163-2116 UR - https://www.unboundmedicine.com/medline/citation/3121269/Nutritional_therapy_of_Crohn's_disease_in_childhood_ L2 - http://www.diseaseinfosearch.org/result/2013 DB - PRIME DP - Unbound Medicine ER -