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Pharmacoeconomic Review Report: Sucroferric Oxyhydroxide (Velphoro): (Vifor Fresenius Medical Care Renal Pharma Ltd.): Indication: For the control of serum phosphorus levels in adult patients with end-stage renal disease on dialysis

Abstract
Sucroferric oxyhydroxide (500 mg; Velphoro) is a non-calcium, iron-based, chewable phosphate binder indicated for the control of serum phosphorus levels in patients with end-stage renal disease (ESRD) receiving dialysis. The starting dosage is three tablets per day (1,500 mg iron) administered as one tablet (500 mg iron) three times daily with meals. The dose is titrated up or down in increments of 500 mg iron (one tablet) per day every two to four weeks until an acceptable serum phosphorus level is reached. The submitted price of sucroferric oxyhydroxide is $4.62 per tablet (daily cost: $13.87 to $18.49). The manufacturer submitted a cost-utility analysis comparing sucroferric oxyhydroxide with sevelamer hydrochloride in adult patients with ESRD receiving dialysis. The analysis was conducted over a lifetime time horizon (assumed to be 10 years) from the perspective of the Canadian health care payer.

Publisher

Canadian Agency for Drugs and Technologies in Health
Ottawa (ON)

Language

eng

PubMed ID

31233296

Citation

Pharmacoeconomic Review Report: Sucroferric Oxyhydroxide (Velphoro): (Vifor Fresenius Medical Care Renal Pharma Ltd.): Indication: For the control of serum phosphorus levels in adult patients with end-stage renal disease on dialysis. Canadian Agency for Drugs and Technologies in Health, 2019, Ottawa (ON).
Pharmacoeconomic Review Report: Sucroferric Oxyhydroxide (Velphoro): (Vifor Fresenius Medical Care Renal Pharma Ltd.): Indication: For the control of serum phosphorus levels in adult patients with end-stage renal disease on dialysis. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019.
(2019). In Pharmacoeconomic Review Report: Sucroferric Oxyhydroxide (Velphoro): (Vifor Fresenius Medical Care Renal Pharma Ltd.): Indication: For the control of serum phosphorus levels in adult patients with end-stage renal disease on dialysis. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health;
Pharmacoeconomic Review Report: Sucroferric Oxyhydroxide (Velphoro): (Vifor Fresenius Medical Care Renal Pharma Ltd.): Indication: For the control of serum phosphorus levels in adult patients with end-stage renal disease on dialysis. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2019.
* Article titles in AMA citation format should be in sentence-case
TY - BOOK T1 - Pharmacoeconomic Review Report: Sucroferric Oxyhydroxide (Velphoro): (Vifor Fresenius Medical Care Renal Pharma Ltd.): Indication: For the control of serum phosphorus levels in adult patients with end-stage renal disease on dialysis Y1 - 2019/02// PY - 2019/6/25/pubmed PY - 2019/6/25/medline PY - 2019/6/25/entrez N2 - Sucroferric oxyhydroxide (500 mg; Velphoro) is a non-calcium, iron-based, chewable phosphate binder indicated for the control of serum phosphorus levels in patients with end-stage renal disease (ESRD) receiving dialysis. The starting dosage is three tablets per day (1,500 mg iron) administered as one tablet (500 mg iron) three times daily with meals. The dose is titrated up or down in increments of 500 mg iron (one tablet) per day every two to four weeks until an acceptable serum phosphorus level is reached. The submitted price of sucroferric oxyhydroxide is $4.62 per tablet (daily cost: $13.87 to $18.49). The manufacturer submitted a cost-utility analysis comparing sucroferric oxyhydroxide with sevelamer hydrochloride in adult patients with ESRD receiving dialysis. The analysis was conducted over a lifetime time horizon (assumed to be 10 years) from the perspective of the Canadian health care payer. PB - Canadian Agency for Drugs and Technologies in Health CY - Ottawa (ON) UR - https://www.unboundmedicine.com/medline/citation/31233296/Pharmacoeconomic_Review_Report:_Sucroferric_Oxyhydroxide_(Velphoro):_(Vifor_Fresenius_Medical_Care_Renal_Pharma_Ltd.):_Indication:_For_the_control_of_serum_phosphorus_levels_in_adult_patients_with_end-stage_renal_disease_on_dialysis L2 - https://www.ncbi.nlm.nih.gov/books/NBK542813 DB - PRIME DP - Unbound Medicine ER -
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