Tags

Type your tag names separated by a space and hit enter

Is There a Correlation Between Preoperative or Postoperative Vitamin D Levels with Pseudarthrosis, Hardware Failure, and Revisions After Lumbar Spine Fusion?
World Neurosurg. 2019 Oct; 130:e431-e437.WN

Abstract

BACKGROUND

Vitamin D deficiency is a well-known cause of postoperative complications in patients undergoing orthopedic surgery. Orthopedic complications seen in vitamin D deficiency include nonunion, pseudarthrosis, and hardware failure. We seek to investigate the relationship between vitamin D deficiency and outcomes after lumbar spinal fusions.

METHODS

A retrospective patient chart review was conducted at a single center for all patients who underwent lumbar spinal fusions from January 2015 to September 2017 with preoperative or postoperative vitamin D laboratory values. We recorded demographics, social history, medications, pre-existing medical conditions, bone density (dual-energy x-ray absorptiometry) T-scores, procedural details, 1-year postoperative Visual Analog Score (VAS), documented pseudarthrosis, revisions, and hardware failure. A total of 150 patients were initially included in the cohort for analysis.

RESULTS

Overall, preoperative and postoperative vitamin D levels were not significantly associated with a vast majority of the patient characteristics studied, including comorbidities, medications, or surgical diagnoses (P > 0.05). Age at surgery was significantly associated with vitamin D levels; older patients had higher serum levels of vitamin D both preoperatively (P = 0.03) and postoperatively (P = 0.01). Those with a higher average body mass index had lower vitamin D in both groups (P = 0.02). Vitamin D levels were not significantly associated with rates of postoperative pseudarthrosis, revision, or hardware complications (P > 0.05). VAS pain score at 1 year and smoking status preoperatively or postoperatively were not associated with vitamin D levels (P > 0.05).

CONCLUSIONS

Both preoperative and postoperative vitamin D levels were not significantly associated with an increased or decreased risk of pseudarthrosis, revision surgery, hardware failure, or 1-year VAS pain score after lumbar spine fusion surgery.

Authors+Show Affiliations

Department of Orthopedic Surgery, University of Miami Hospital, Miami, Florida, USA. Electronic address: Chester.Donnally@jhsmiami.org.Department of Education, University of Miami Leonard M. Miller School of Medicine, Miami, Florida, USA.Department of Education, University of Miami Leonard M. Miller School of Medicine, Miami, Florida, USA.Department of Education, University of Miami Leonard M. Miller School of Medicine, Miami, Florida, USA.Department of Education, University of Miami Leonard M. Miller School of Medicine, Miami, Florida, USA.Department of Orthopedic Surgery, University of Miami Hospital, Miami, Florida, USA.Department of Orthopedic Surgery, University of Miami Hospital, Miami, Florida, USA.Department of Orthopedic Surgery, University of Miami Hospital, Miami, Florida, USA.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31238168

Citation

Donnally, Chester J., et al. "Is There a Correlation Between Preoperative or Postoperative Vitamin D Levels With Pseudarthrosis, Hardware Failure, and Revisions After Lumbar Spine Fusion?" World Neurosurgery, vol. 130, 2019, pp. e431-e437.
Donnally CJ, Sheu JI, Bondar KJ, et al. Is There a Correlation Between Preoperative or Postoperative Vitamin D Levels with Pseudarthrosis, Hardware Failure, and Revisions After Lumbar Spine Fusion? World Neurosurg. 2019;130:e431-e437.
Donnally, C. J., Sheu, J. I., Bondar, K. J., Mouhanna, J. N., Li, D. J., Butler, A. J., Rush, A. J., & Gjolaj, J. P. (2019). Is There a Correlation Between Preoperative or Postoperative Vitamin D Levels with Pseudarthrosis, Hardware Failure, and Revisions After Lumbar Spine Fusion? World Neurosurgery, 130, e431-e437. https://doi.org/10.1016/j.wneu.2019.06.109
Donnally CJ, et al. Is There a Correlation Between Preoperative or Postoperative Vitamin D Levels With Pseudarthrosis, Hardware Failure, and Revisions After Lumbar Spine Fusion. World Neurosurg. 2019;130:e431-e437. PubMed PMID: 31238168.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Is There a Correlation Between Preoperative or Postoperative Vitamin D Levels with Pseudarthrosis, Hardware Failure, and Revisions After Lumbar Spine Fusion? AU - Donnally,Chester J,3rd AU - Sheu,Jonathan I, AU - Bondar,Kevin J, AU - Mouhanna,Joelle N, AU - Li,Deborah J, AU - Butler,Alexander J, AU - Rush,Augustus J,3rd AU - Gjolaj,Joseph P, Y1 - 2019/06/22/ PY - 2019/05/09/received PY - 2019/06/13/revised PY - 2019/06/14/accepted PY - 2019/6/27/pubmed PY - 2020/1/23/medline PY - 2019/6/26/entrez KW - Hardware failure KW - Outcomes KW - Pseudoarthrosis KW - Spine fusion KW - Spine surgery KW - Vitamin D SP - e431 EP - e437 JF - World neurosurgery JO - World Neurosurg VL - 130 N2 - BACKGROUND: Vitamin D deficiency is a well-known cause of postoperative complications in patients undergoing orthopedic surgery. Orthopedic complications seen in vitamin D deficiency include nonunion, pseudarthrosis, and hardware failure. We seek to investigate the relationship between vitamin D deficiency and outcomes after lumbar spinal fusions. METHODS: A retrospective patient chart review was conducted at a single center for all patients who underwent lumbar spinal fusions from January 2015 to September 2017 with preoperative or postoperative vitamin D laboratory values. We recorded demographics, social history, medications, pre-existing medical conditions, bone density (dual-energy x-ray absorptiometry) T-scores, procedural details, 1-year postoperative Visual Analog Score (VAS), documented pseudarthrosis, revisions, and hardware failure. A total of 150 patients were initially included in the cohort for analysis. RESULTS: Overall, preoperative and postoperative vitamin D levels were not significantly associated with a vast majority of the patient characteristics studied, including comorbidities, medications, or surgical diagnoses (P > 0.05). Age at surgery was significantly associated with vitamin D levels; older patients had higher serum levels of vitamin D both preoperatively (P = 0.03) and postoperatively (P = 0.01). Those with a higher average body mass index had lower vitamin D in both groups (P = 0.02). Vitamin D levels were not significantly associated with rates of postoperative pseudarthrosis, revision, or hardware complications (P > 0.05). VAS pain score at 1 year and smoking status preoperatively or postoperatively were not associated with vitamin D levels (P > 0.05). CONCLUSIONS: Both preoperative and postoperative vitamin D levels were not significantly associated with an increased or decreased risk of pseudarthrosis, revision surgery, hardware failure, or 1-year VAS pain score after lumbar spine fusion surgery. SN - 1878-8769 UR - https://www.unboundmedicine.com/medline/citation/31238168/Is_There_a_Correlation_Between_Preoperative_or_Postoperative_Vitamin_D_Levels_with_Pseudarthrosis_Hardware_Failure_and_Revisions_After_Lumbar_Spine_Fusion L2 - https://linkinghub.elsevier.com/retrieve/pii/S1878-8750(19)31661-4 DB - PRIME DP - Unbound Medicine ER -