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Solitary orbital myofibroma in a child: A rare case report with literature review.
Indian J Ophthalmol 2019; 67(7):1240-1245IJ

Abstract

Myofibroma is a rare benign mesenchymal tumor of uncertain histogenesis. A six-year-old boy presented with a unilateral lower eyelid mass of six weeks' duration. MRI revealed a circumscribed mass in the inferolateral orbit with bony erosion. A systemic examination was unremarkable. Excision with histopathology revealed a partially infiltrative spindle cell tumor with bland nuclear morphology expressing smooth muscle actin and muscle-specific actin, compatible with myofibroma. Solitary myofibroma is a rare childhood orbital tumor and may clinico-radiologically closely mimic a malignancy. Histopathology and immunohistochemistry can help reach a definitive diagnosis. Systemic evaluation and close follow up are crucial in such cases.

Authors+Show Affiliations

Ophthalmic Plastic Surgery, Orbit and Ocular Oncology Services, The Operation Eyesight Universal Institute for Eye Cancer, Bhubaneswar, Odisha, India.Ophthalmic Plastic Surgery, Orbit and Ocular Oncology Services, The Operation Eyesight Universal Institute for Eye Cancer, Bhubaneswar, Odisha, India.Kanupriya Dalmia Ophthalmic Pathology Laboratory, L.V. Prasad Eye Institute, Mithu Tulsi Chanrai Campus, Bhubaneswar, Odisha, India.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

31238482

Citation

Madhuri, Bejjanki Kavya, et al. "Solitary Orbital Myofibroma in a Child: a Rare Case Report With Literature Review." Indian Journal of Ophthalmology, vol. 67, no. 7, 2019, pp. 1240-1245.
Madhuri BK, Tripathy D, Mittal R. Solitary orbital myofibroma in a child: A rare case report with literature review. Indian J Ophthalmol. 2019;67(7):1240-1245.
Madhuri, B. K., Tripathy, D., & Mittal, R. (2019). Solitary orbital myofibroma in a child: A rare case report with literature review. Indian Journal of Ophthalmology, 67(7), pp. 1240-1245. doi:10.4103/ijo.IJO_1553_18.
Madhuri BK, Tripathy D, Mittal R. Solitary Orbital Myofibroma in a Child: a Rare Case Report With Literature Review. Indian J Ophthalmol. 2019;67(7):1240-1245. PubMed PMID: 31238482.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Solitary orbital myofibroma in a child: A rare case report with literature review. AU - Madhuri,Bejjanki Kavya, AU - Tripathy,Devjyoti, AU - Mittal,Ruchi, PY - 2019/6/27/entrez PY - 2019/6/27/pubmed PY - 2019/9/5/medline KW - Benign KW - bone erosion KW - children KW - myofibromatosis KW - orbital myofibroma SP - 1240 EP - 1245 JF - Indian journal of ophthalmology JO - Indian J Ophthalmol VL - 67 IS - 7 N2 - Myofibroma is a rare benign mesenchymal tumor of uncertain histogenesis. A six-year-old boy presented with a unilateral lower eyelid mass of six weeks' duration. MRI revealed a circumscribed mass in the inferolateral orbit with bony erosion. A systemic examination was unremarkable. Excision with histopathology revealed a partially infiltrative spindle cell tumor with bland nuclear morphology expressing smooth muscle actin and muscle-specific actin, compatible with myofibroma. Solitary myofibroma is a rare childhood orbital tumor and may clinico-radiologically closely mimic a malignancy. Histopathology and immunohistochemistry can help reach a definitive diagnosis. Systemic evaluation and close follow up are crucial in such cases. SN - 1998-3689 UR - https://www.unboundmedicine.com/medline/citation/31238482/Solitary_orbital_myofibroma_in_a_child:_A_rare_case_report_with_literature_review L2 - http://www.ijo.in/article.asp?issn=0301-4738;year=2019;volume=67;issue=7;spage=1240;epage=1245;aulast=Madhuri DB - PRIME DP - Unbound Medicine ER -