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Selenium and Health: An Update on the Situation in the Middle East and North Africa.
Nutrients 2019; 11(7)N

Abstract

Selenium (Se) is an important trace element that should be present in the diet of all age groups to provide an adequate intake. Se is incorporated in 25 known selenoproteins, which mediate the biological effects of Se including, immune response regulation, maintenance of thyroid function, antioxidant defense, and anti-inflammatory actions. A balanced intake of Se is critical to achieve health benefits because depending on its status, Se has been found to play physiological roles or contribute to the pathophysiology of various diseases including, neurodegenerative diseases, diabetes, cancer, and cardiovascular disorders. Se status and intake are very important to be known for a specific population as the levels of Se are highly variable among different populations and regions. In the Middle East and North African (MENA) region, very little is known about the status of Se. Studies available show that Se status is widely variable with some countries being deficient, some over sufficient, and some sufficient. This variability was apparent even within the same country between regions. In this review, we summarized the key roles of Se in health and disease and discussed the available data on Se status and intake among countries of the MENA region.

Authors+Show Affiliations

Department of Pharmaceutical Sciences, College of Pharmacy, QU health, Qatar University, P.O. Box 2713, Doha, Qatar.Department of Nutrition, College of Health Sciences, QU health, Qatar University, P.O. Box 2713, Doha, Qatar.Department of Pharmaceutical Sciences, College of Pharmacy, QU health, Qatar University, P.O. Box 2713, Doha, Qatar. aagouni@qu.edu.qa.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31252568

Citation

Ibrahim, Sohayla A Z., et al. "Selenium and Health: an Update On the Situation in the Middle East and North Africa." Nutrients, vol. 11, no. 7, 2019.
Ibrahim SAZ, Kerkadi A, Agouni A. Selenium and Health: An Update on the Situation in the Middle East and North Africa. Nutrients. 2019;11(7).
Ibrahim, S. A. Z., Kerkadi, A., & Agouni, A. (2019). Selenium and Health: An Update on the Situation in the Middle East and North Africa. Nutrients, 11(7), doi:10.3390/nu11071457.
Ibrahim SAZ, Kerkadi A, Agouni A. Selenium and Health: an Update On the Situation in the Middle East and North Africa. Nutrients. 2019 Jun 27;11(7) PubMed PMID: 31252568.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Selenium and Health: An Update on the Situation in the Middle East and North Africa. AU - Ibrahim,Sohayla A Z, AU - Kerkadi,Abdelhamid, AU - Agouni,Abdelali, Y1 - 2019/06/27/ PY - 2019/05/29/received PY - 2019/06/15/revised PY - 2019/06/19/accepted PY - 2019/6/30/entrez PY - 2019/6/30/pubmed PY - 2019/6/30/medline KW - Middle East KW - North Africa KW - chronic diseases KW - selenium JF - Nutrients JO - Nutrients VL - 11 IS - 7 N2 - Selenium (Se) is an important trace element that should be present in the diet of all age groups to provide an adequate intake. Se is incorporated in 25 known selenoproteins, which mediate the biological effects of Se including, immune response regulation, maintenance of thyroid function, antioxidant defense, and anti-inflammatory actions. A balanced intake of Se is critical to achieve health benefits because depending on its status, Se has been found to play physiological roles or contribute to the pathophysiology of various diseases including, neurodegenerative diseases, diabetes, cancer, and cardiovascular disorders. Se status and intake are very important to be known for a specific population as the levels of Se are highly variable among different populations and regions. In the Middle East and North African (MENA) region, very little is known about the status of Se. Studies available show that Se status is widely variable with some countries being deficient, some over sufficient, and some sufficient. This variability was apparent even within the same country between regions. In this review, we summarized the key roles of Se in health and disease and discussed the available data on Se status and intake among countries of the MENA region. SN - 2072-6643 UR - https://www.unboundmedicine.com/medline/citation/31252568/Selenium_and_Health:_An_Update_on_the_Situation_in_the_Middle_East_and_North_Africa L2 - http://www.mdpi.com/resolver?pii=nu11071457 DB - PRIME DP - Unbound Medicine ER -