Tags

Type your tag names separated by a space and hit enter

Influenza vaccination and secondary prevention of cardiovascular disease among Taiwanese elders-A propensity score-matched follow-up study.
PLoS One. 2019; 14(7):e0219172.Plos

Abstract

The present study aimed to evaluate the association between influenza vaccination and the secondary prevention of cardiovascular disease (CVD) among elderly persons. This retrospective cohort study used the Geriatric Dataset of Taiwan's National Health Insurance Research Database (2000-2013). Patients aged ≥ 65 years who had been hospitalized for the first episodes of myocardial infarction were eligible. The vaccinated cohort comprised patients who received one dose of influenza vaccine within 180 days after discharge. The unvaccinated cohort included those who did not receive influenza vaccination and was propensity score-matched (1:1) for known CVD risk factors. All-cause death, acute myocardial infarction or cardiovascular death, and hospitalization for heart failure were assessed 1 year after the 181st day after hospital discharge. Compared with the matched cohort (n = 4,350), the vaccinated cohort (n = 4,350) had significantly lower incidences of all-cause death (hazard ratios [HR] 0.82, 95% CI [confidence interval] 0.73-0.92), myocardial infarction or cardiovascular death (HR 0.84, 95% CI 0.74-0.96), and hospitalization for heart failure (HR 0.83, 95% CI 0.74-0.92). The association between influenza vaccination and reduction of CVDs was similar across different subgroups. Cumulative incidence curves of the CVDs of interest for the two cohorts separated within the initial 3 months of follow-up (P < 0.05). Influenza vaccination was associated with a reduced risk of CVD in the elderly population with previous myocardial infarction.

Authors+Show Affiliations

Division of Infection Control and Biosafety, Centers for Disease Control, Taipei, Taiwan.Division of Infectious Diseases, Department of Internal Medicine, National Yang-Ming University Hospital, Yilan County, Taiwan.National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli County, Taiwan.Divisions of Nephrology, Taipei Veterans General Hospital, Taipei, Taiwan. Department of Medicine, Taipei City Hospital Heping Fuyou Branch, Taipei, Taiwan.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

31260487

Citation

Wu, Hao-Hsin, et al. "Influenza Vaccination and Secondary Prevention of Cardiovascular Disease Among Taiwanese elders-A Propensity Score-matched Follow-up Study." PloS One, vol. 14, no. 7, 2019, pp. e0219172.
Wu HH, Chang YY, Kuo SC, et al. Influenza vaccination and secondary prevention of cardiovascular disease among Taiwanese elders-A propensity score-matched follow-up study. PLoS ONE. 2019;14(7):e0219172.
Wu, H. H., Chang, Y. Y., Kuo, S. C., & Chen, Y. T. (2019). Influenza vaccination and secondary prevention of cardiovascular disease among Taiwanese elders-A propensity score-matched follow-up study. PloS One, 14(7), e0219172. https://doi.org/10.1371/journal.pone.0219172
Wu HH, et al. Influenza Vaccination and Secondary Prevention of Cardiovascular Disease Among Taiwanese elders-A Propensity Score-matched Follow-up Study. PLoS ONE. 2019;14(7):e0219172. PubMed PMID: 31260487.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Influenza vaccination and secondary prevention of cardiovascular disease among Taiwanese elders-A propensity score-matched follow-up study. AU - Wu,Hao-Hsin, AU - Chang,Yea-Yuan, AU - Kuo,Shu-Chen, AU - Chen,Yung-Tai, Y1 - 2019/07/01/ PY - 2018/04/10/received PY - 2019/06/18/accepted PY - 2019/7/2/entrez PY - 2019/7/2/pubmed PY - 2019/7/2/medline SP - e0219172 EP - e0219172 JF - PloS one JO - PLoS ONE VL - 14 IS - 7 N2 - The present study aimed to evaluate the association between influenza vaccination and the secondary prevention of cardiovascular disease (CVD) among elderly persons. This retrospective cohort study used the Geriatric Dataset of Taiwan's National Health Insurance Research Database (2000-2013). Patients aged ≥ 65 years who had been hospitalized for the first episodes of myocardial infarction were eligible. The vaccinated cohort comprised patients who received one dose of influenza vaccine within 180 days after discharge. The unvaccinated cohort included those who did not receive influenza vaccination and was propensity score-matched (1:1) for known CVD risk factors. All-cause death, acute myocardial infarction or cardiovascular death, and hospitalization for heart failure were assessed 1 year after the 181st day after hospital discharge. Compared with the matched cohort (n = 4,350), the vaccinated cohort (n = 4,350) had significantly lower incidences of all-cause death (hazard ratios [HR] 0.82, 95% CI [confidence interval] 0.73-0.92), myocardial infarction or cardiovascular death (HR 0.84, 95% CI 0.74-0.96), and hospitalization for heart failure (HR 0.83, 95% CI 0.74-0.92). The association between influenza vaccination and reduction of CVDs was similar across different subgroups. Cumulative incidence curves of the CVDs of interest for the two cohorts separated within the initial 3 months of follow-up (P < 0.05). Influenza vaccination was associated with a reduced risk of CVD in the elderly population with previous myocardial infarction. SN - 1932-6203 UR - https://www.unboundmedicine.com/medline/citation/31260487/Influenza_vaccination_and_secondary_prevention_of_cardiovascular_disease_among_Taiwanese_elders_A_propensity_score_matched_follow_up_study_ L2 - http://dx.plos.org/10.1371/journal.pone.0219172 DB - PRIME DP - Unbound Medicine ER -