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Phytochemicals in Prostate Cancer: From Bioactive Molecules to Upcoming Therapeutic Agents.
Nutrients 2019; 11(7)N

Abstract

Prostate cancer is a heterogeneous disease, the second deadliest malignancy in men and the most commonly diagnosed cancer among men. Traditional plants have been applied to handle various diseases and to develop new drugs. Medicinal plants are potential sources of natural bioactive compounds that include alkaloids, phenolic compounds, terpenes, and steroids. Many of these naturally-occurring bioactive constituents possess promising chemopreventive properties. In this sense, the aim of the present review is to provide a detailed overview of the role of plant-derived phytochemicals in prostate cancers, including the contribution of plant extracts and its corresponding isolated compounds.

Authors+Show Affiliations

Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam 44340847, Iran.Antimicrobial and Biocontrol Agents Unit, Department of Biochemistry, Faculty of Science, University of Yaounde I, Ngoa Ekelle, Annex Fac. Sci, Yaounde 812, Cameroon.Institute for Medical Research and Medicinal Plants Studies, Yaoundé 13033, Cameroon.Antimicrobial Agents Unit, Laboratory for Phytobiochemistry and Medicinal Plants Studies, Department of Biochemistry, Faculty of Science, University of Yaoundé I, Messa-Yaoundé 812, Cameroon.Applied Microbiology, Biotechnology and Nanotechnology Laboratory, Department of Microbiology, Edo University, Iyamho, Edo State 300271, Nigeria.Department of Urology, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran 1989934148, Iran.Department of Agriculture and Animal Health, University of South Africa, Private Bag X6, Florida 1710, South Africa.Department of Nutrition and Dietetics, Faculty of Pharmacy, University of Concepcion, Concepcion 4070386, Chile. mmartorell@udec.cl.Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA.LEPABE-Department of Chemical Engineering, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, s/n, 4200-465 Porto, Portugal. c.fortunae@gmail.com.Faculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal. ncmartins@med.up.pt. Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal. ncmartins@med.up.pt.Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong SAR, China. williamcscho@gmail.com.Zabol Medicinal Plants Research Center, Zabol University of Medical Sciences, Zabol 61615-585, Iran. javad.sharifirad@gmail.com.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

31261861

Citation

Salehi, Bahare, et al. "Phytochemicals in Prostate Cancer: From Bioactive Molecules to Upcoming Therapeutic Agents." Nutrients, vol. 11, no. 7, 2019.
Salehi B, Fokou PVT, Yamthe LRT, et al. Phytochemicals in Prostate Cancer: From Bioactive Molecules to Upcoming Therapeutic Agents. Nutrients. 2019;11(7).
Salehi, B., Fokou, P. V. T., Yamthe, L. R. T., Tali, B. T., Adetunji, C. O., Rahavian, A., ... Sharifi-Rad, J. (2019). Phytochemicals in Prostate Cancer: From Bioactive Molecules to Upcoming Therapeutic Agents. Nutrients, 11(7), doi:10.3390/nu11071483.
Salehi B, et al. Phytochemicals in Prostate Cancer: From Bioactive Molecules to Upcoming Therapeutic Agents. Nutrients. 2019 Jun 29;11(7) PubMed PMID: 31261861.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Phytochemicals in Prostate Cancer: From Bioactive Molecules to Upcoming Therapeutic Agents. AU - Salehi,Bahare, AU - Fokou,Patrick Valere Tsouh, AU - Yamthe,Lauve Rachel Tchokouaha, AU - Tali,Brice Tchatat, AU - Adetunji,Charles Oluwaseun, AU - Rahavian,Amirhossein, AU - Mudau,Fhatuwani Nixwell, AU - Martorell,Miquel, AU - Setzer,William N, AU - Rodrigues,Célia F, AU - Martins,Natália, AU - Cho,William C, AU - Sharifi-Rad,Javad, Y1 - 2019/06/29/ PY - 2019/05/14/received PY - 2019/06/22/revised PY - 2019/06/27/accepted PY - 2019/7/3/entrez PY - 2019/7/3/pubmed PY - 2019/7/3/medline KW - medicinal plants KW - phytotherapy KW - plant formulas KW - prostate cancer KW - secondary metabolites JF - Nutrients JO - Nutrients VL - 11 IS - 7 N2 - Prostate cancer is a heterogeneous disease, the second deadliest malignancy in men and the most commonly diagnosed cancer among men. Traditional plants have been applied to handle various diseases and to develop new drugs. Medicinal plants are potential sources of natural bioactive compounds that include alkaloids, phenolic compounds, terpenes, and steroids. Many of these naturally-occurring bioactive constituents possess promising chemopreventive properties. In this sense, the aim of the present review is to provide a detailed overview of the role of plant-derived phytochemicals in prostate cancers, including the contribution of plant extracts and its corresponding isolated compounds. SN - 2072-6643 UR - https://www.unboundmedicine.com/medline/citation/31261861/Phytochemicals_in_Prostate_Cancer:_From_Bioactive_Molecules_to_Upcoming_Therapeutic_Agents DB - PRIME DP - Unbound Medicine ER -