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Outpatient management of diabetic ketoacidosis.
Am J Dis Child 1988; 142(4):448-50AJ

Abstract

An analysis of 63 pediatric diabetic patient visits to an emergency department for diabetic ketoacidosis was performed. Of 27 patients with a serum pH less than 7.20 or bicarbonate concentration less than 10 mmol/L (10 mEq/L) at admission, 25 (92%) had persistence of metabolic acidosis after three hours of outpatient therapy and were hospitalized. Of 36 patients with a serum pH greater than or equal to 7.20 or a bicarbonate concentration greater than or equal to 10 mmol/L (10 mEq/L) at admission, 34 (94%) had resolution of metabolic acidosis within three hours of initiating outpatient therapy and were discharged from the emergency department. The relapse rate in each group was similar. The initial serum glucose concentration accurately predicted duration of therapy necessary to resolve metabolic acidosis in the majority of patients discharged. Certain diabetic children can be treated for diabetic ketoacidosis with therapy administered in an outpatient setting. Most patients with an initial serum pH of 7.20 or higher or a bicarbonate concentration of 10 mmol/L (10 mEq/L) or higher will experience resolution of acidosis and tolerate feeding within three hours of initiating treatment.

Authors+Show Affiliations

Department of Pediatrics, Medical College of Wisconsin, Children's Hospital, Milwaukee 53233.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

3126645

Citation

Bonadio, W A., et al. "Outpatient Management of Diabetic Ketoacidosis." American Journal of Diseases of Children (1960), vol. 142, no. 4, 1988, pp. 448-50.
Bonadio WA, Gutzeit MF, Losek JD, et al. Outpatient management of diabetic ketoacidosis. Am J Dis Child. 1988;142(4):448-50.
Bonadio, W. A., Gutzeit, M. F., Losek, J. D., & Smith, D. S. (1988). Outpatient management of diabetic ketoacidosis. American Journal of Diseases of Children (1960), 142(4), pp. 448-50.
Bonadio WA, et al. Outpatient Management of Diabetic Ketoacidosis. Am J Dis Child. 1988;142(4):448-50. PubMed PMID: 3126645.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outpatient management of diabetic ketoacidosis. AU - Bonadio,W A, AU - Gutzeit,M F, AU - Losek,J D, AU - Smith,D S, PY - 1988/4/1/pubmed PY - 1988/4/1/medline PY - 1988/4/1/entrez SP - 448 EP - 50 JF - American journal of diseases of children (1960) JO - Am. J. Dis. Child. VL - 142 IS - 4 N2 - An analysis of 63 pediatric diabetic patient visits to an emergency department for diabetic ketoacidosis was performed. Of 27 patients with a serum pH less than 7.20 or bicarbonate concentration less than 10 mmol/L (10 mEq/L) at admission, 25 (92%) had persistence of metabolic acidosis after three hours of outpatient therapy and were hospitalized. Of 36 patients with a serum pH greater than or equal to 7.20 or a bicarbonate concentration greater than or equal to 10 mmol/L (10 mEq/L) at admission, 34 (94%) had resolution of metabolic acidosis within three hours of initiating outpatient therapy and were discharged from the emergency department. The relapse rate in each group was similar. The initial serum glucose concentration accurately predicted duration of therapy necessary to resolve metabolic acidosis in the majority of patients discharged. Certain diabetic children can be treated for diabetic ketoacidosis with therapy administered in an outpatient setting. Most patients with an initial serum pH of 7.20 or higher or a bicarbonate concentration of 10 mmol/L (10 mEq/L) or higher will experience resolution of acidosis and tolerate feeding within three hours of initiating treatment. SN - 0002-922X UR - https://www.unboundmedicine.com/medline/citation/3126645/Outpatient_management_of_diabetic_ketoacidosis_ DB - PRIME DP - Unbound Medicine ER -