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Bio-evaluation of functional date bars using rats as model organism against hypercholesterolemia.
Lipids Health Dis. 2019 Jul 04; 18(1):148.LH

Abstract

BACKGROUND

The present research project was designed to evaluate the cholesterol lowering potential of different date varieties including one exotic (Ajwa) and three Pakistani varieties (Aseel, Khudravi, Hallawi).

METHODS

The albino rats were divided into six groups on the basis of different diets which includes, control having basal diet, high cholesterol high sucrose diet, high cholesterol high sucrose diet plus Khudravi dates, high cholesterol high sucrose diet plus Hallawi dates, high cholesterol high sucrose diet plus Aseel dates, high cholesterol high sucrose diet plus Ajwa dates to evaluate maximum cholesterol lowering potential of each date variety.

RESULTS

The results showed that Hallawi and Ajwa have lower crude fiber content as 2.02 ± 0.03% and 2.43 ± 0.04% however, lowest crude fat content (0.26 ± 0.01%) was also observed in ajwa. Mineral profile depicted that sodium (9.50-18.00 mg/100 g) was found to be in lesser amount among all varieties whereas, higher amount of potassium (465.00 to 887.20 mg/100 g) depicted that it is suitable for people having hypertension. Higher amount of reducing sugar was also observed in ajwa (79.45 ± 1.22%) followed by Hallawi (77.68 ± 1.42%). Total phenolic contents were found higher in Aseel (291.36 mg/100 g) whereas, minimum was observed in Khudravi (232.64 mg/100 g). Furthermore, date varieties were also examined rat modeling to evaluate their maximum cholesterol lowering efficiency. Ajwa and Hallawi were observed to suppress the cholesterol efficiently as 110 mg/dL and 103 mg/dL respectively. On the basis of chemical profiling and other parameters, two date varieties Ajwa and Hallawi showed almost similar results and found to have maximum serum cholesterol, LDL and triglyceride reduction potential with good kidney and liver functions. Functional date bar was also developed by using Hallawi variety andsubjected to sensory evaluation.

CONCLUSION

In nutshell, Hallawi date variety was considered as better cholesterol lowering potential among other indigenous varieties and very close to Ajwa variety. So that Hallawi can be used to suppress the deadly effects of obesity and allied discrepancies particularly hypercholesterolemia.

Authors+Show Affiliations

Institute of Home and Food Sciences, Government College University, Faisalabad, Pakistan. sajid_ft@yahoo.com.Institute of Home and Food Sciences, Government College University, Faisalabad, Pakistan.Institute of Home and Food Sciences, Government College University, Faisalabad, Pakistan.Institute of Home and Food Sciences, Government College University, Faisalabad, Pakistan.Institute of Home and Food Sciences, Government College University, Faisalabad, Pakistan.Vice Chancellor Secretariat, University of the Gambia, Banjul, The Gambia.College of Food and Agricultural Sciences, King Saud University, Riyadh, Saudi Arabia.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31272450

Citation

Arshad, Muhammad Sajid, et al. "Bio-evaluation of Functional Date Bars Using Rats as Model Organism Against Hypercholesterolemia." Lipids in Health and Disease, vol. 18, no. 1, 2019, p. 148.
Arshad MS, Batool SM, Khan MK, et al. Bio-evaluation of functional date bars using rats as model organism against hypercholesterolemia. Lipids Health Dis. 2019;18(1):148.
Arshad, M. S., Batool, S. M., Khan, M. K., Imran, M., Ahmad, M. H., Anjum, F. M., & Hussain, S. (2019). Bio-evaluation of functional date bars using rats as model organism against hypercholesterolemia. Lipids in Health and Disease, 18(1), 148. https://doi.org/10.1186/s12944-019-1087-3
Arshad MS, et al. Bio-evaluation of Functional Date Bars Using Rats as Model Organism Against Hypercholesterolemia. Lipids Health Dis. 2019 Jul 4;18(1):148. PubMed PMID: 31272450.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bio-evaluation of functional date bars using rats as model organism against hypercholesterolemia. AU - Arshad,Muhammad Sajid, AU - Batool,Syeda Mamoona, AU - Khan,Muhammad Kamran, AU - Imran,Muhammad, AU - Ahmad,Muhammad Haseeb, AU - Anjum,Faqir Muhammad, AU - Hussain,Shahzad, Y1 - 2019/07/04/ PY - 2019/04/04/received PY - 2019/06/10/accepted PY - 2019/7/6/entrez PY - 2019/7/6/pubmed PY - 2019/12/31/medline KW - Antioxidant profile KW - Date varieties KW - Hypercholesterolemia KW - Rats modelling SP - 148 EP - 148 JF - Lipids in health and disease JO - Lipids Health Dis VL - 18 IS - 1 N2 - BACKGROUND: The present research project was designed to evaluate the cholesterol lowering potential of different date varieties including one exotic (Ajwa) and three Pakistani varieties (Aseel, Khudravi, Hallawi). METHODS: The albino rats were divided into six groups on the basis of different diets which includes, control having basal diet, high cholesterol high sucrose diet, high cholesterol high sucrose diet plus Khudravi dates, high cholesterol high sucrose diet plus Hallawi dates, high cholesterol high sucrose diet plus Aseel dates, high cholesterol high sucrose diet plus Ajwa dates to evaluate maximum cholesterol lowering potential of each date variety. RESULTS: The results showed that Hallawi and Ajwa have lower crude fiber content as 2.02 ± 0.03% and 2.43 ± 0.04% however, lowest crude fat content (0.26 ± 0.01%) was also observed in ajwa. Mineral profile depicted that sodium (9.50-18.00 mg/100 g) was found to be in lesser amount among all varieties whereas, higher amount of potassium (465.00 to 887.20 mg/100 g) depicted that it is suitable for people having hypertension. Higher amount of reducing sugar was also observed in ajwa (79.45 ± 1.22%) followed by Hallawi (77.68 ± 1.42%). Total phenolic contents were found higher in Aseel (291.36 mg/100 g) whereas, minimum was observed in Khudravi (232.64 mg/100 g). Furthermore, date varieties were also examined rat modeling to evaluate their maximum cholesterol lowering efficiency. Ajwa and Hallawi were observed to suppress the cholesterol efficiently as 110 mg/dL and 103 mg/dL respectively. On the basis of chemical profiling and other parameters, two date varieties Ajwa and Hallawi showed almost similar results and found to have maximum serum cholesterol, LDL and triglyceride reduction potential with good kidney and liver functions. Functional date bar was also developed by using Hallawi variety andsubjected to sensory evaluation. CONCLUSION: In nutshell, Hallawi date variety was considered as better cholesterol lowering potential among other indigenous varieties and very close to Ajwa variety. So that Hallawi can be used to suppress the deadly effects of obesity and allied discrepancies particularly hypercholesterolemia. SN - 1476-511X UR - https://www.unboundmedicine.com/medline/citation/31272450/Bio_evaluation_of_functional_date_bars_using_rats_as_model_organism_against_hypercholesterolemia_ L2 - https://lipidworld.biomedcentral.com/articles/10.1186/s12944-019-1087-3 DB - PRIME DP - Unbound Medicine ER -