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Examination of formal thought disorder and its clinical correlates with the Turkish Version of the Thought and Language Disorder Scale (TALD-TR) in schizophrenia.
Compr Psychiatry 2019; 93:7-13CP

Abstract

BACKGROUND

Formal thought disorder (FTD) is considered to be a fundamental feature of schizophrenia. This study aims to analyze psychometric properties of the Turkish version of "Thought and Language Disorder Scale (TALD)" and investigate the relationship between FTD and various clinical characteristics in patients with schizophrenia.

METHODS

TALD was adapted into Turkish and applied to a total of 149 participants of which 114 had DSM-5 psychiatric diagnoses (schizophrenia N = 70, mania N = 20, depression N = 24) and 35 were healthy controls. Positive and Negative Syndrome Scale (PANSS), Hamilton Depression Rating Scale, Young Mania Rating Scale, and Clinical Global Impression were administered to detect illness severity.

RESULTS

The principal component analyses revealed that the Turkish version of TALD (TALD-TR) consisted of four factors including the Objective Positive (OP), Subjective Negative (SN), Objective Negative (ON) and Subjective Positive (SP) symptom dimensions which were in line with the original TALD factorial structure. It was concluded that TALD-TR shows strong construct validity and high interrater reliability. The correlation analyses with TALD-TR and PANSS showed that there are positive correlations between the TALD-TR total score and the PANSS total and subscale scores. Each diagnostic group showed the distinct pattern of FTD. The mania group exhibited the highest mean total score in the OP, whereas the schizophrenia group exhibited the highest mean total score in the ON factor. In the schizophrenia group, the severity of FTD correlated positively with duration of illness and negatively with age at onset of illness.

CONCLUSION

Adaptation of TALD into different languages seems to be possible, bringing in an international tool for research on FTD.

Authors+Show Affiliations

Department of Psychiatry, Hacettepe University Faculty of Medicine, Ankara, Turkey. Electronic address: mutluemre12@gmail.com.Department of Psychiatry, Hacettepe University Faculty of Medicine, Ankara, Turkey.Department of Psychiatry, Hacettepe University Faculty of Medicine, Ankara, Turkey.Department of Psychiatry, Hacettepe University Faculty of Medicine, Ankara, Turkey.Department of Psychiatry, Hacettepe University Faculty of Medicine, Ankara, Turkey.Department of Psychiatry, Numune Training and Research Hospital, Ankara, Turkey.Department of Psychiatry, Numune Training and Research Hospital, Ankara, Turkey.Department of Psychiatry, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31276902

Citation

Mutlu, Emre, et al. "Examination of Formal Thought Disorder and Its Clinical Correlates With the Turkish Version of the Thought and Language Disorder Scale (TALD-TR) in Schizophrenia." Comprehensive Psychiatry, vol. 93, 2019, pp. 7-13.
Mutlu E, Yazıcı MK, Barışkın E, et al. Examination of formal thought disorder and its clinical correlates with the Turkish Version of the Thought and Language Disorder Scale (TALD-TR) in schizophrenia. Compr Psychiatry. 2019;93:7-13.
Mutlu, E., Yazıcı, M. K., Barışkın, E., Ertuğrul, A., Gürel, Ş. C., Gürkan, Ş., ... Yağcıoğlu, A. E. A. (2019). Examination of formal thought disorder and its clinical correlates with the Turkish Version of the Thought and Language Disorder Scale (TALD-TR) in schizophrenia. Comprehensive Psychiatry, 93, pp. 7-13. doi:10.1016/j.comppsych.2019.06.003.
Mutlu E, et al. Examination of Formal Thought Disorder and Its Clinical Correlates With the Turkish Version of the Thought and Language Disorder Scale (TALD-TR) in Schizophrenia. Compr Psychiatry. 2019;93:7-13. PubMed PMID: 31276902.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Examination of formal thought disorder and its clinical correlates with the Turkish Version of the Thought and Language Disorder Scale (TALD-TR) in schizophrenia. AU - Mutlu,Emre, AU - Yazıcı,M Kâzım, AU - Barışkın,Elif, AU - Ertuğrul,Aygün, AU - Gürel,Ş Can, AU - Gürkan,Şahin, AU - Göka,Erol, AU - Yağcıoğlu,A Elif Anıl, Y1 - 2019/06/17/ PY - 2018/12/30/received PY - 2019/06/02/revised PY - 2019/06/03/accepted PY - 2019/7/6/pubmed PY - 2019/7/6/medline PY - 2019/7/6/entrez KW - Depression KW - Formal thought disorder KW - Language processing KW - Mania KW - Schizophrenia SP - 7 EP - 13 JF - Comprehensive psychiatry JO - Compr Psychiatry VL - 93 N2 - BACKGROUND: Formal thought disorder (FTD) is considered to be a fundamental feature of schizophrenia. This study aims to analyze psychometric properties of the Turkish version of "Thought and Language Disorder Scale (TALD)" and investigate the relationship between FTD and various clinical characteristics in patients with schizophrenia. METHODS: TALD was adapted into Turkish and applied to a total of 149 participants of which 114 had DSM-5 psychiatric diagnoses (schizophrenia N = 70, mania N = 20, depression N = 24) and 35 were healthy controls. Positive and Negative Syndrome Scale (PANSS), Hamilton Depression Rating Scale, Young Mania Rating Scale, and Clinical Global Impression were administered to detect illness severity. RESULTS: The principal component analyses revealed that the Turkish version of TALD (TALD-TR) consisted of four factors including the Objective Positive (OP), Subjective Negative (SN), Objective Negative (ON) and Subjective Positive (SP) symptom dimensions which were in line with the original TALD factorial structure. It was concluded that TALD-TR shows strong construct validity and high interrater reliability. The correlation analyses with TALD-TR and PANSS showed that there are positive correlations between the TALD-TR total score and the PANSS total and subscale scores. Each diagnostic group showed the distinct pattern of FTD. The mania group exhibited the highest mean total score in the OP, whereas the schizophrenia group exhibited the highest mean total score in the ON factor. In the schizophrenia group, the severity of FTD correlated positively with duration of illness and negatively with age at onset of illness. CONCLUSION: Adaptation of TALD into different languages seems to be possible, bringing in an international tool for research on FTD. SN - 1532-8384 UR - https://www.unboundmedicine.com/medline/citation/31276902/Examination_of_formal_thought_disorder_and_its_clinical_correlates_with_the_Turkish_Version_of_the_Thought_and_Language_Disorder_Scale__TALD_TR__in_schizophrenia_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0010-440X(19)30026-4 DB - PRIME DP - Unbound Medicine ER -