Tags

Type your tag names separated by a space and hit enter

Congenital infiltrating lipomatosis of the face: A subtype of hemifacial hyperplasia.
Int J Pediatr Otorhinolaryngol 2019; 125:107-112IJ

Abstract

OBJECTIVE

To investigate the clinical, imaging and pathological features of congenital infiltrating lipomatosis of the face (CILF) and to discuss whether it is a subtype of hemifacial hyperplasia (HH).

METHODS

Sixteen patients diagnosed with CILF were included in this study. All patients had undergone panoramic radiography and spiral CT examinations. Thirteen patients received biopsy, surgery treatment and pathological examination. The clinical documentation and imaging data were retrospectively reviewed.

RESULTS

The cheeks (14/16), parotid glands (12/16), tongues (9/16), masticatory muscles (8/16) and the lips (7/16) were the most frequently affected soft tissue organs. The maxilla (14/16), zygoma (13/16), mandible (13/16) were involved among the maxillofacial bones. Dental malformations included macrodontia (8/16), poor formation of the roots (7/16), accelerated tooth germ development or premature eruption of permanent teeth (7/16) and missing of the permanent teeth (4/16). All malformations were restricted to one side of the face and did not trespass the middle line. Pathologically, CILF was featured by the diffuse infiltration of redundant mature adipose tissue into the tissue of the affected organ.

CONCLUSION

CILF is a congenital developmental facial malformation characterized by infiltration of nonencapsulated, mature adipose tissue, resulting in facial soft and hard tissue hypertrophy and dental malformations in hemifacial structures. CILF could be considered as a subtype of HH.

Authors+Show Affiliations

Department of Oral and Maxillofacial Radiology, School and Hospital of Stomatology, Peking University, 22 South Zhongguancun Avenue, Haidian District, Beijing, 100081, PR China; National Engineering Laboratory for Digital and Material Technology of Stomatology, School and Hospital of Stomatology, Peking University, 22 South Zhongguancun Avenue, Haidian District, Beijing, 100081, PR China. Electronic address: pkusunru1994@163.com.National Engineering Laboratory for Digital and Material Technology of Stomatology, School and Hospital of Stomatology, Peking University, 22 South Zhongguancun Avenue, Haidian District, Beijing, 100081, PR China; Key Laboratory of Oral Pathology, School and Hospital of Stomatology, Peking University, 22 South Zhongguancun Avenue, Haidian District, Beijing, 100081, PR China. Electronic address: lisa_sun@bjmu.edu.cn.Department of Oral and Maxillofacial Radiology, School and Hospital of Stomatology, Peking University, 22 South Zhongguancun Avenue, Haidian District, Beijing, 100081, PR China; National Engineering Laboratory for Digital and Material Technology of Stomatology, School and Hospital of Stomatology, Peking University, 22 South Zhongguancun Avenue, Haidian District, Beijing, 100081, PR China. Electronic address: kqgang@bjmu.edu.cn.Department of Oral and Maxillofacial Radiology, School and Hospital of Stomatology, Peking University, 22 South Zhongguancun Avenue, Haidian District, Beijing, 100081, PR China; National Engineering Laboratory for Digital and Material Technology of Stomatology, School and Hospital of Stomatology, Peking University, 22 South Zhongguancun Avenue, Haidian District, Beijing, 100081, PR China. Electronic address: sunzhipeng@bjmu.edu.cn.Department of Oral and Maxillofacial Radiology, School and Hospital of Stomatology, Peking University, 22 South Zhongguancun Avenue, Haidian District, Beijing, 100081, PR China; National Engineering Laboratory for Digital and Material Technology of Stomatology, School and Hospital of Stomatology, Peking University, 22 South Zhongguancun Avenue, Haidian District, Beijing, 100081, PR China. Electronic address: kqzhao@bjmu.edu.cn.Department of Oral and Maxillofacial Radiology, School and Hospital of Stomatology, Peking University, 22 South Zhongguancun Avenue, Haidian District, Beijing, 100081, PR China; National Engineering Laboratory for Digital and Material Technology of Stomatology, School and Hospital of Stomatology, Peking University, 22 South Zhongguancun Avenue, Haidian District, Beijing, 100081, PR China. Electronic address: kqxcma@bjmu.edu.cn.Department of Oral and Maxillofacial Radiology, School and Hospital of Stomatology, Peking University, 22 South Zhongguancun Avenue, Haidian District, Beijing, 100081, PR China; National Engineering Laboratory for Digital and Material Technology of Stomatology, School and Hospital of Stomatology, Peking University, 22 South Zhongguancun Avenue, Haidian District, Beijing, 100081, PR China. Electronic address: 771946970@qq.com.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31280031

Citation

Sun, Ru, et al. "Congenital Infiltrating Lipomatosis of the Face: a Subtype of Hemifacial Hyperplasia." International Journal of Pediatric Otorhinolaryngology, vol. 125, 2019, pp. 107-112.
Sun R, Sun L, Li G, et al. Congenital infiltrating lipomatosis of the face: A subtype of hemifacial hyperplasia. Int J Pediatr Otorhinolaryngol. 2019;125:107-112.
Sun, R., Sun, L., Li, G., Sun, Z., Zhao, Y., Ma, X., & Sun, C. (2019). Congenital infiltrating lipomatosis of the face: A subtype of hemifacial hyperplasia. International Journal of Pediatric Otorhinolaryngology, 125, pp. 107-112. doi:10.1016/j.ijporl.2019.06.032.
Sun R, et al. Congenital Infiltrating Lipomatosis of the Face: a Subtype of Hemifacial Hyperplasia. Int J Pediatr Otorhinolaryngol. 2019 Jun 30;125:107-112. PubMed PMID: 31280031.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Congenital infiltrating lipomatosis of the face: A subtype of hemifacial hyperplasia. AU - Sun,Ru, AU - Sun,Lisha, AU - Li,Gang, AU - Sun,Zhipeng, AU - Zhao,Yanping, AU - Ma,Xuchen, AU - Sun,Chongke, Y1 - 2019/06/30/ PY - 2019/01/30/received PY - 2019/06/27/revised PY - 2019/06/28/accepted PY - 2019/7/8/pubmed PY - 2019/7/8/medline PY - 2019/7/8/entrez KW - Congenital KW - Dental KW - Face KW - Hyperplasia KW - Lipomatosis KW - Malformation SP - 107 EP - 112 JF - International journal of pediatric otorhinolaryngology JO - Int. J. Pediatr. Otorhinolaryngol. VL - 125 N2 - OBJECTIVE: To investigate the clinical, imaging and pathological features of congenital infiltrating lipomatosis of the face (CILF) and to discuss whether it is a subtype of hemifacial hyperplasia (HH). METHODS: Sixteen patients diagnosed with CILF were included in this study. All patients had undergone panoramic radiography and spiral CT examinations. Thirteen patients received biopsy, surgery treatment and pathological examination. The clinical documentation and imaging data were retrospectively reviewed. RESULTS: The cheeks (14/16), parotid glands (12/16), tongues (9/16), masticatory muscles (8/16) and the lips (7/16) were the most frequently affected soft tissue organs. The maxilla (14/16), zygoma (13/16), mandible (13/16) were involved among the maxillofacial bones. Dental malformations included macrodontia (8/16), poor formation of the roots (7/16), accelerated tooth germ development or premature eruption of permanent teeth (7/16) and missing of the permanent teeth (4/16). All malformations were restricted to one side of the face and did not trespass the middle line. Pathologically, CILF was featured by the diffuse infiltration of redundant mature adipose tissue into the tissue of the affected organ. CONCLUSION: CILF is a congenital developmental facial malformation characterized by infiltration of nonencapsulated, mature adipose tissue, resulting in facial soft and hard tissue hypertrophy and dental malformations in hemifacial structures. CILF could be considered as a subtype of HH. SN - 1872-8464 UR - https://www.unboundmedicine.com/medline/citation/31280031/Congenital_infiltrating_lipomatosis_of_the_face:_A_subtype_of_hemifacial_hyperplasia L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-5876(19)30306-4 DB - PRIME DP - Unbound Medicine ER -