Tags

Type your tag names separated by a space and hit enter

Central Giant Cell Granuloma Treated with Intralesional Corticosteroid Injections and Bisphosphonates: A Long-Term Follow-Up Case Study.

Abstract

Central giant cell granuloma (CGCG) is a benign intraosseous lesion of the head and neck with potential for aggressive and locally destructive behaviour. Lesions of the maxilla tend to expand more than those of the mandible due to the thinner cortices and spongy tissue of this location. Surgical removal is the most common treatment; however, it may be disfiguring in aggressive cases, especially for lesions located in the maxilla. Alternative treatments, such as intralesional corticosteroid injections, have been performed with satisfactory results. We report a case of a 12-year-old female patient with a CGCG of the left maxilla that was treated with 40 doses of intralesional triamcinolone acetonide infiltrations combined with alendronate sodium and calcium carbonate. Clinical and imaging follow-up over 12 years demonstrates improvement in the patient's condition.

Authors+Show Affiliations

Department of Oral Pathology, School of Dentistry, Federal University of Ceara, Rua Monsenhor Furtado, Fortaleza, Ceara, 60430-355, Brazil.Department of Oral Pathology, School of Dentistry, Federal University of Para, Avenida Augusto Correa, 01, Belem, Para, 66075-110, Brazil.Department of Oral and Maxillofacial Surgery, School of Dentistry, Federal University of Para, Avenida Augusto Correa, Avenida Augusto Correa, 01, Belem, Para, 66075-110, Brazil.Department of Oral Pathology, School of Dentistry, Federal University of Para, Avenida Augusto Correa, 01, Belem, Para, 66075-110, Brazil.Department of Oral Pathology, School of Dentistry, Federal University of Para, Avenida Augusto Correa, 01, Belem, Para, 66075-110, Brazil., Belem, Brazil.Department of Oral and Maxillofacial Surgery, School of Dentistry, Federal University of Para, Avenida Augusto Correa, Avenida Augusto Correa, 01, Belem, Para, 66075-110, Brazil.Department of Oral Pathology, School of Dentistry, Federal University of Para, Avenida Augusto Correa, 01, Belem, Para, 66075-110, Brazil. radface@hotmail.com. Cell Culture Laboratory, Department of Oral Pathology, School of Dentistry, Federal University of Para - UFPA - Institute of Health Sciences, Avenida Augusto Correa, 01, Belem, Para, 66075-110, Brazil. radface@hotmail.com.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31297738

Citation

de Mendonça, Raíssa Pinheiro, et al. "Central Giant Cell Granuloma Treated With Intralesional Corticosteroid Injections and Bisphosphonates: a Long-Term Follow-Up Case Study." Head and Neck Pathology, 2019.
de Mendonça RP, Mitre GP, Real FH, et al. Central Giant Cell Granuloma Treated with Intralesional Corticosteroid Injections and Bisphosphonates: A Long-Term Follow-Up Case Study. Head Neck Pathol. 2019.
de Mendonça, R. P., Mitre, G. P., Real, F. H., da Silva Kataoka, M. S., de Melo Alves Júnior, S., Vianna, P., ... de Jesus Viana Pinheiro, J. (2019). Central Giant Cell Granuloma Treated with Intralesional Corticosteroid Injections and Bisphosphonates: A Long-Term Follow-Up Case Study. Head and Neck Pathology, doi:10.1007/s12105-019-01053-x.
de Mendonça RP, et al. Central Giant Cell Granuloma Treated With Intralesional Corticosteroid Injections and Bisphosphonates: a Long-Term Follow-Up Case Study. Head Neck Pathol. 2019 Jul 11; PubMed PMID: 31297738.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Central Giant Cell Granuloma Treated with Intralesional Corticosteroid Injections and Bisphosphonates: A Long-Term Follow-Up Case Study. AU - de Mendonça,Raíssa Pinheiro, AU - Mitre,Geovanni Pereira, AU - Real,Flavio Henrique, AU - da Silva Kataoka,Maria Sueli, AU - de Melo Alves Júnior,Sérgio, AU - Vianna,Paulo, AU - Da Silva Júnior,Newton Guerreiro, AU - de Jesus Viana Pinheiro,João, Y1 - 2019/07/11/ PY - 2019/03/18/received PY - 2019/07/06/accepted PY - 2019/7/13/entrez KW - Corticosteroid KW - Giant cell KW - Granuloma KW - Injections KW - Intralesional KW - Triamcinolone acetonide JF - Head and neck pathology JO - Head Neck Pathol N2 - Central giant cell granuloma (CGCG) is a benign intraosseous lesion of the head and neck with potential for aggressive and locally destructive behaviour. Lesions of the maxilla tend to expand more than those of the mandible due to the thinner cortices and spongy tissue of this location. Surgical removal is the most common treatment; however, it may be disfiguring in aggressive cases, especially for lesions located in the maxilla. Alternative treatments, such as intralesional corticosteroid injections, have been performed with satisfactory results. We report a case of a 12-year-old female patient with a CGCG of the left maxilla that was treated with 40 doses of intralesional triamcinolone acetonide infiltrations combined with alendronate sodium and calcium carbonate. Clinical and imaging follow-up over 12 years demonstrates improvement in the patient's condition. SN - 1936-0568 UR - https://www.unboundmedicine.com/medline/citation/31297738/Central_Giant_Cell_Granuloma_Treated_with_Intralesional_Corticosteroid_Injections_and_Bisphosphonates:_A_Long-Term_Follow-Up_Case_Study L2 - https://dx.doi.org/10.1007/s12105-019-01053-x DB - PRIME DP - Unbound Medicine ER -