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Composition and Potential Health Benefits of Pomegranate: A Review.
Curr Pharm Des. 2019; 25(16):1817-1827.CP

Abstract

BACKGROUND

Pomegranate (Punica granatum L.) fruits are widely consumed and used as preventive and therapeutic agents since ancient times. Pomegranate is a rich source of a variety of phytochemicals, which are responsible for its strong antioxidative and anti-inflammatory potential.

OBJECTIVE

The aim of this review is to provide an up-to-date overview of the current knowledge of chemical structure and potential health benefits of pomegranate.

METHODS

A comprehensive search of available literature.

RESULTS

The review of the literature confirms that juice and extracts obtained from different parts of this plant, including fruit peel, seeds, and leaves exert health benefits in both in vitro and in vivo studies. The antidiabetic, antihypertensive, antimicrobial and anti-tumour effects of pomegranate fruit are of particular scientific and clinical interest.

CONCLUSION

Further investigations are required to clarify the mechanism of action of the bioactive ingredients and to reveal full potential of pomegranate as both preventive and therapeutic agent.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Vučić V
Centre of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, University of Belgrade, studentskitry 1, Belgrade, Serbia.
Grabež M
Faculty of Medicine, University of Banja Luka, Bosnia and Herzegovina, Republika Srpska.
Trchounian A
Department of Biochemistry, Microbiology and Biotechnology, Yerevan State University, Yerevan 0025, Armenia.
Arsić A
Centre of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, University of Belgrade, studentskitry 1, Belgrade, Serbia.

MeSH

Anti-Inflammatory AgentsAntioxidantsFruitFruit and Vegetable JuicesPhytochemicalsPlant ExtractsPomegranate

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

31298147

Citation

Vučić, Vesna, et al. "Composition and Potential Health Benefits of Pomegranate: a Review." Current Pharmaceutical Design, vol. 25, no. 16, 2019, pp. 1817-1827.
Vučić V, Grabež M, Trchounian A, et al. Composition and Potential Health Benefits of Pomegranate: A Review. Curr Pharm Des. 2019;25(16):1817-1827.
Vučić, V., Grabež, M., Trchounian, A., & Arsić, A. (2019). Composition and Potential Health Benefits of Pomegranate: A Review. Current Pharmaceutical Design, 25(16), 1817-1827. https://doi.org/10.2174/1381612825666190708183941
Vučić V, et al. Composition and Potential Health Benefits of Pomegranate: a Review. Curr Pharm Des. 2019;25(16):1817-1827. PubMed PMID: 31298147.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Composition and Potential Health Benefits of Pomegranate: A Review. AU - Vučić,Vesna, AU - Grabež,Milkica, AU - Trchounian,Armen, AU - Arsić,Aleksandra, PY - 2019/03/30/received PY - 2019/06/24/accepted PY - 2019/7/13/pubmed PY - 2020/3/4/medline PY - 2019/7/13/entrez KW - Pomegranate KW - antioxidant KW - cancer KW - inflammatory disease KW - metabolic disease KW - polyphenols KW - pomegranate juice KW - pomegranate peel. SP - 1817 EP - 1827 JF - Current pharmaceutical design JO - Curr Pharm Des VL - 25 IS - 16 N2 - BACKGROUND: Pomegranate (Punica granatum L.) fruits are widely consumed and used as preventive and therapeutic agents since ancient times. Pomegranate is a rich source of a variety of phytochemicals, which are responsible for its strong antioxidative and anti-inflammatory potential. OBJECTIVE: The aim of this review is to provide an up-to-date overview of the current knowledge of chemical structure and potential health benefits of pomegranate. METHODS: A comprehensive search of available literature. RESULTS: The review of the literature confirms that juice and extracts obtained from different parts of this plant, including fruit peel, seeds, and leaves exert health benefits in both in vitro and in vivo studies. The antidiabetic, antihypertensive, antimicrobial and anti-tumour effects of pomegranate fruit are of particular scientific and clinical interest. CONCLUSION: Further investigations are required to clarify the mechanism of action of the bioactive ingredients and to reveal full potential of pomegranate as both preventive and therapeutic agent. SN - 1873-4286 UR - https://www.unboundmedicine.com/medline/citation/31298147/Composition_and_Potential_Health_Benefits_of_Pomegranate:_A_Review_ DB - PRIME DP - Unbound Medicine ER -