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Cathodal tDCS increases stop-signal reaction time.
Cogn Affect Behav Neurosci. 2019 10; 19(5):1129-1142.CA

Abstract

Transcranial direct current stimulation (tDCS) is a noninvasive method of modulating human brain activity and potentially alters performance in cognitive tasks. Often it is assumed that effects of tDCS modulation depend on the polarity-anodal stimulation typically boost cognitive processes whereas cathodal stimulation hampers them. While most tDCS research focusses on the effects of anodal stimulation, cathodal tDCS effects are underexplored. In the present study, cathodal tDCS over the right dorsolateral prefrontal cortex (rDLPFC) was used to potentially hamper the response inhibition process as measured by the stop-signal task (SST). A 9 cm2 cathode was always positioned over the rDLPFC while the 35 cm2 anode was placed over the left deltoid. We contrasted a cathodal stimulation condition (that is assumed to reduce neural processing) with sham stimulation and expected a decrease in SST performance after cathodal tDCS, as evidenced by an increase in stop-signal reaction time (SSRT). In a sample of N = 45 healthy adults, a significant Time × tDCS condition interaction emerged, indicating an increase in SSRT after cathodal tDCS. In a recent study by Friehs and Frings (Journal of Experimental Psychology: Human Perception and Performance, 2018), using a similar study design and stimulation protocol, single-session anodal tDCS over the rDLPFC was used to enhance SST performance as indicated by an acceleration of SSRT. In concert, these results suggest that response inhibition is tied to the neural state of the rDLPFC.

Authors+Show Affiliations

Cognitive Psychology, University of Trier, Trier, Germany. friehs@uni-trier.de.Cognitive Psychology, University of Trier, Trier, Germany.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31313248

Citation

Friehs, Maximilian A., and Christian Frings. "Cathodal tDCS Increases Stop-signal Reaction Time." Cognitive, Affective & Behavioral Neuroscience, vol. 19, no. 5, 2019, pp. 1129-1142.
Friehs MA, Frings C. Cathodal tDCS increases stop-signal reaction time. Cogn Affect Behav Neurosci. 2019;19(5):1129-1142.
Friehs, M. A., & Frings, C. (2019). Cathodal tDCS increases stop-signal reaction time. Cognitive, Affective & Behavioral Neuroscience, 19(5), 1129-1142. https://doi.org/10.3758/s13415-019-00740-0
Friehs MA, Frings C. Cathodal tDCS Increases Stop-signal Reaction Time. Cogn Affect Behav Neurosci. 2019;19(5):1129-1142. PubMed PMID: 31313248.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cathodal tDCS increases stop-signal reaction time. AU - Friehs,Maximilian A, AU - Frings,Christian, PY - 2019/7/18/pubmed PY - 2020/9/15/medline PY - 2019/7/18/entrez KW - Cognitive control KW - Neural network KW - Prefrontal cortex KW - Stop-Signal Task KW - tDCS SP - 1129 EP - 1142 JF - Cognitive, affective & behavioral neuroscience JO - Cogn Affect Behav Neurosci VL - 19 IS - 5 N2 - Transcranial direct current stimulation (tDCS) is a noninvasive method of modulating human brain activity and potentially alters performance in cognitive tasks. Often it is assumed that effects of tDCS modulation depend on the polarity-anodal stimulation typically boost cognitive processes whereas cathodal stimulation hampers them. While most tDCS research focusses on the effects of anodal stimulation, cathodal tDCS effects are underexplored. In the present study, cathodal tDCS over the right dorsolateral prefrontal cortex (rDLPFC) was used to potentially hamper the response inhibition process as measured by the stop-signal task (SST). A 9 cm2 cathode was always positioned over the rDLPFC while the 35 cm2 anode was placed over the left deltoid. We contrasted a cathodal stimulation condition (that is assumed to reduce neural processing) with sham stimulation and expected a decrease in SST performance after cathodal tDCS, as evidenced by an increase in stop-signal reaction time (SSRT). In a sample of N = 45 healthy adults, a significant Time × tDCS condition interaction emerged, indicating an increase in SSRT after cathodal tDCS. In a recent study by Friehs and Frings (Journal of Experimental Psychology: Human Perception and Performance, 2018), using a similar study design and stimulation protocol, single-session anodal tDCS over the rDLPFC was used to enhance SST performance as indicated by an acceleration of SSRT. In concert, these results suggest that response inhibition is tied to the neural state of the rDLPFC. SN - 1531-135X UR - https://www.unboundmedicine.com/medline/citation/31313248/Cathodal_tDCS_increases_stop_signal_reaction_time_ L2 - https://dx.doi.org/10.3758/s13415-019-00740-0 DB - PRIME DP - Unbound Medicine ER -