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Antioxidant Potential, Phytochemicals Composition, and Metal Contents of Datura alba.
Biomed Res Int 2019; 2019:2403718BR

Abstract

This study investigated the phytochemical characteristics and antioxidant activity in leaves, roots, stem, flower, and seed parts of Datura alba (D. alba). The study also assessed the heavy metal (Cr, Mn, Zn, and Cu) accumulation in each part of the plant. Among the phytochemicals, alkaloids were found only in leaves while tannins, flavonoids, and phenols were present in all parts of the plant. For antioxidant activity, free radical scavenging assay for 2,2-diphenyl-1-picrylhydrazyl (DPPH) was performed using ascorbic acid as the standard. Higher activity was shown by stem extract in methanol and leaf extract in n-hexane, ethyl acetate, and chloroform. Furthermore, all the target heavy metals were detected in all plant sections with the highest concentration of Zn in leaves and Cu in stem, root, flower, and seed. Due to stronger antioxidant potential and phytochemical composition, D. alba could prove as valuable prospect in pharmaceutical formulations by taking part in the antioxidant defense system against generation of free radicals.

Authors+Show Affiliations

Department of Chemistry, Abdul Wali Khan University, Mardan, Pakistan.Department of Chemistry, Abdul Wali Khan University, Mardan, Pakistan.Department of Environmental Sciences, Abdul Wali Khan University, Mardan, Pakistan.Department of Biochemistry, Abdul Wali Khan University, Mardan, Pakistan.Medicinal, Aromatic and Poisonous Plants Research Center (MAPRC), College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.Medicinal, Aromatic and Poisonous Plants Research Center (MAPRC), College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia. Phytochemistry Department, National Research Centre, P.O. Box 1262233, El Bohouth St., Dokki, Giza, Egypt. Department of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.Medicinal, Aromatic and Poisonous Plants Research Center (MAPRC), College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia. Department of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31317024

Citation

Khan, Waliullah, et al. "Antioxidant Potential, Phytochemicals Composition, and Metal Contents of Datura Alba." BioMed Research International, vol. 2019, 2019, p. 2403718.
Khan W, Subhan S, Shams DF, et al. Antioxidant Potential, Phytochemicals Composition, and Metal Contents of Datura alba. Biomed Res Int. 2019;2019:2403718.
Khan, W., Subhan, S., Shams, D. F., Afridi, S. G., Ullah, R., Shahat, A. A., & Alqahtani, A. S. (2019). Antioxidant Potential, Phytochemicals Composition, and Metal Contents of Datura alba. BioMed Research International, 2019, p. 2403718. doi:10.1155/2019/2403718.
Khan W, et al. Antioxidant Potential, Phytochemicals Composition, and Metal Contents of Datura Alba. Biomed Res Int. 2019;2019:2403718. PubMed PMID: 31317024.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant Potential, Phytochemicals Composition, and Metal Contents of Datura alba. AU - Khan,Waliullah, AU - Subhan,Sidra, AU - Shams,Dilawar Farhan, AU - Afridi,Sahib Gul, AU - Ullah,Riaz, AU - Shahat,Abdelaaty A, AU - Alqahtani,Ali S, Y1 - 2019/06/17/ PY - 2019/03/19/received PY - 2019/05/28/accepted PY - 2019/7/19/entrez PY - 2019/7/19/pubmed PY - 2019/7/19/medline SP - 2403718 EP - 2403718 JF - BioMed research international JO - Biomed Res Int VL - 2019 N2 - This study investigated the phytochemical characteristics and antioxidant activity in leaves, roots, stem, flower, and seed parts of Datura alba (D. alba). The study also assessed the heavy metal (Cr, Mn, Zn, and Cu) accumulation in each part of the plant. Among the phytochemicals, alkaloids were found only in leaves while tannins, flavonoids, and phenols were present in all parts of the plant. For antioxidant activity, free radical scavenging assay for 2,2-diphenyl-1-picrylhydrazyl (DPPH) was performed using ascorbic acid as the standard. Higher activity was shown by stem extract in methanol and leaf extract in n-hexane, ethyl acetate, and chloroform. Furthermore, all the target heavy metals were detected in all plant sections with the highest concentration of Zn in leaves and Cu in stem, root, flower, and seed. Due to stronger antioxidant potential and phytochemical composition, D. alba could prove as valuable prospect in pharmaceutical formulations by taking part in the antioxidant defense system against generation of free radicals. SN - 2314-6141 UR - https://www.unboundmedicine.com/medline/citation/31317024/Antioxidant_Potential,_Phytochemicals_Composition,_and_Metal_Contents_of_Datura_alba L2 - https://dx.doi.org/10.1155/2019/2403718 DB - PRIME DP - Unbound Medicine ER -