TY - JOUR T1 - Antioxidant Potential, Phytochemicals Composition, and Metal Contents of Datura alba. AU - Khan,Waliullah, AU - Subhan,Sidra, AU - Shams,Dilawar Farhan, AU - Afridi,Sahib Gul, AU - Ullah,Riaz, AU - Shahat,Abdelaaty A, AU - Alqahtani,Ali S, Y1 - 2019/06/17/ PY - 2019/03/19/received PY - 2019/05/28/accepted PY - 2019/7/19/entrez PY - 2019/7/19/pubmed PY - 2019/12/21/medline SP - 2403718 EP - 2403718 JF - BioMed research international JO - Biomed Res Int VL - 2019 N2 - This study investigated the phytochemical characteristics and antioxidant activity in leaves, roots, stem, flower, and seed parts of Datura alba (D. alba). The study also assessed the heavy metal (Cr, Mn, Zn, and Cu) accumulation in each part of the plant. Among the phytochemicals, alkaloids were found only in leaves while tannins, flavonoids, and phenols were present in all parts of the plant. For antioxidant activity, free radical scavenging assay for 2,2-diphenyl-1-picrylhydrazyl (DPPH) was performed using ascorbic acid as the standard. Higher activity was shown by stem extract in methanol and leaf extract in n-hexane, ethyl acetate, and chloroform. Furthermore, all the target heavy metals were detected in all plant sections with the highest concentration of Zn in leaves and Cu in stem, root, flower, and seed. Due to stronger antioxidant potential and phytochemical composition, D. alba could prove as valuable prospect in pharmaceutical formulations by taking part in the antioxidant defense system against generation of free radicals. SN - 2314-6141 UR - https://www.unboundmedicine.com/medline/citation/31317024/Antioxidant_Potential_Phytochemicals_Composition_and_Metal_Contents_of_Datura_alba_ DB - PRIME DP - Unbound Medicine ER -