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Pineal region tumors: Long-term results of endoscopic third ventriculostomy and concurrent tumor biopsy with a single entry approach in a series of 64 cases.
Clin Neurol Neurosurg 2019; 184:105418CN

Abstract

OBJECTIVES

Endoscopic third ventriculostomy and concurrent biopsy is increasingly used in management of the pineal region tumors. Our objective was to assess the results of single entry approach to surgically manage the tumors of the pineal region.

PATIENTS AND METHODS

A retrospective study was designed, and a series of 64 consecutive patients (31 male, 33 female) with pineal region tumor undergoing endoscopic third ventriculostomy and concurrent biopsy of the tumor was undertaken.

RESULTS

A total of 64 patients underwent simultaneous endoscopic third ventriculostomy and biopsy of the pineal tumors with a single entry approach. A positive initial diagnosis was established in 97% of patients. 5 patients (7%) required the insertion of an external ventricular drain which was removed in all patients after 72 h but in one case (1%) undergoing permanent VP shunt insertion. The postoperative complications were divided into two transient and permanent complications. The transient complications included intraventricular hemorrhage (18%), seizure (1 to two episodes of seizure) (5%), diabetes insipidus (3%) and meningitis (3%) all were successfully managed. The only permanent complication was memory deficits occurred in one patient (1%). There was no mortality rate in current study.

CONCLUSION

The results of this study support the safety and efficacy of endoscopic third ventriculostomy and concurrent biopsy of the pineal region tumors as a less invasive surgical method associated with low morbidity and mortality rate. Our data demonstrated how simultaneous endoscopic third ventriculostomy and biopsy of the pineal region tumors with a single entry approach can produce favorable results.

Authors+Show Affiliations

Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: mdsamadian@gmail.com.Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: Ehsannazari1992@yahoo.com.Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: bluestar.1500@yahoo.com.Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: dr.kavehebrahimzadeh@gmail.com.Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: Gibnow@yahoo.com.Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: alimousavi65@yahoo.com.Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: dromidvarrezaei@gmail.com.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31319237

Citation

Samadian, Mohammad, et al. "Pineal Region Tumors: Long-term Results of Endoscopic Third Ventriculostomy and Concurrent Tumor Biopsy With a Single Entry Approach in a Series of 64 Cases." Clinical Neurology and Neurosurgery, vol. 184, 2019, p. 105418.
Samadian M, Maloumeh EN, Shiravand S, et al. Pineal region tumors: Long-term results of endoscopic third ventriculostomy and concurrent tumor biopsy with a single entry approach in a series of 64 cases. Clin Neurol Neurosurg. 2019;184:105418.
Samadian, M., Maloumeh, E. N., Shiravand, S., Ebrahimzadeh, K., Sharifi, G., Mousavinejad, A., & Rezaei, O. (2019). Pineal region tumors: Long-term results of endoscopic third ventriculostomy and concurrent tumor biopsy with a single entry approach in a series of 64 cases. Clinical Neurology and Neurosurgery, 184, p. 105418. doi:10.1016/j.clineuro.2019.105418.
Samadian M, et al. Pineal Region Tumors: Long-term Results of Endoscopic Third Ventriculostomy and Concurrent Tumor Biopsy With a Single Entry Approach in a Series of 64 Cases. Clin Neurol Neurosurg. 2019;184:105418. PubMed PMID: 31319237.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pineal region tumors: Long-term results of endoscopic third ventriculostomy and concurrent tumor biopsy with a single entry approach in a series of 64 cases. AU - Samadian,Mohammad, AU - Maloumeh,Ehsan Nazari, AU - Shiravand,Sepideh, AU - Ebrahimzadeh,Kaveh, AU - Sharifi,Guive, AU - Mousavinejad,Ali, AU - Rezaei,Omidvar, Y1 - 2019/07/08/ PY - 2019/05/30/received PY - 2019/07/04/revised PY - 2019/07/06/accepted PY - 2019/7/19/pubmed PY - 2019/7/19/medline PY - 2019/7/19/entrez KW - Endoscopic third ventriculostomy KW - Hydrocephalus KW - Pineal region tumors KW - Tumor biopsy SP - 105418 EP - 105418 JF - Clinical neurology and neurosurgery JO - Clin Neurol Neurosurg VL - 184 N2 - OBJECTIVES: Endoscopic third ventriculostomy and concurrent biopsy is increasingly used in management of the pineal region tumors. Our objective was to assess the results of single entry approach to surgically manage the tumors of the pineal region. PATIENTS AND METHODS: A retrospective study was designed, and a series of 64 consecutive patients (31 male, 33 female) with pineal region tumor undergoing endoscopic third ventriculostomy and concurrent biopsy of the tumor was undertaken. RESULTS: A total of 64 patients underwent simultaneous endoscopic third ventriculostomy and biopsy of the pineal tumors with a single entry approach. A positive initial diagnosis was established in 97% of patients. 5 patients (7%) required the insertion of an external ventricular drain which was removed in all patients after 72 h but in one case (1%) undergoing permanent VP shunt insertion. The postoperative complications were divided into two transient and permanent complications. The transient complications included intraventricular hemorrhage (18%), seizure (1 to two episodes of seizure) (5%), diabetes insipidus (3%) and meningitis (3%) all were successfully managed. The only permanent complication was memory deficits occurred in one patient (1%). There was no mortality rate in current study. CONCLUSION: The results of this study support the safety and efficacy of endoscopic third ventriculostomy and concurrent biopsy of the pineal region tumors as a less invasive surgical method associated with low morbidity and mortality rate. Our data demonstrated how simultaneous endoscopic third ventriculostomy and biopsy of the pineal region tumors with a single entry approach can produce favorable results. SN - 1872-6968 UR - https://www.unboundmedicine.com/medline/citation/31319237/Pineal_region_tumors:_Long-term_results_of_endoscopic_third_ventriculostomy_and_concurrent_tumor_biopsy_with_a_single_entry_approach_in_a_series_of_64_cases L2 - https://linkinghub.elsevier.com/retrieve/pii/S0303-8467(19)30214-8 DB - PRIME DP - Unbound Medicine ER -