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New classifications of gastroesophageal reflux disease: an improvement for patient management?
Expert Rev Gastroenterol Hepatol 2019; 13(8):761-769ER

Abstract

Introduction: Gastroesophageal reflux disease (GERD) is a very common and often debilitating disease. In the broad spectrum of GERD phenotypes, three main groups may be traditionally distinguished: 1) patients only affected by esophageal and/or extra-esophageal symptoms; 2) patients with erosive esophagitis and 3) patients with further complications. Areas covered: This review provides an overview on the current classifications of GERD patients, and their impact on their management. Expert opinion: In 2017, the GERD Consensus Working Group focused the attention on patients unresponsive to PPIs. In this scenario, a diagnosis of GERD might be confirmed by evident signs of erosive esophagitis and the finding of pH or multichannel intraluminal impedance-pH tests, such as more than 6%. The 'Lyon Consensus' panel of experts confirmed that positive indices of reflux-symptom association, without other altered parameters, represent reflux hypersensitivity. GERD requires a customized management; it is crucial to assess frequency and severity of symptoms and their response to an optimal course of therapy as well as to explore the endoscopic alterations and consider other diagnoses responsible for persistent symptoms.

Authors+Show Affiliations

a Unit of Gastroenterology and Digestive Endoscopy, University Campus Bio Medico , Rome , Italy.a Unit of Gastroenterology and Digestive Endoscopy, University Campus Bio Medico , Rome , Italy.a Unit of Gastroenterology and Digestive Endoscopy, University Campus Bio Medico , Rome , Italy.a Unit of Gastroenterology and Digestive Endoscopy, University Campus Bio Medico , Rome , Italy.a Unit of Gastroenterology and Digestive Endoscopy, University Campus Bio Medico , Rome , Italy.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31327288

Citation

Ribolsi, Mentore, et al. "New Classifications of Gastroesophageal Reflux Disease: an Improvement for Patient Management?" Expert Review of Gastroenterology & Hepatology, vol. 13, no. 8, 2019, pp. 761-769.
Ribolsi M, Giordano A, Guarino MPL, et al. New classifications of gastroesophageal reflux disease: an improvement for patient management? Expert Rev Gastroenterol Hepatol. 2019;13(8):761-769.
Ribolsi, M., Giordano, A., Guarino, M. P. L., Tullio, A., & Cicala, M. (2019). New classifications of gastroesophageal reflux disease: an improvement for patient management? Expert Review of Gastroenterology & Hepatology, 13(8), pp. 761-769. doi:10.1080/17474124.2019.1645596.
Ribolsi M, et al. New Classifications of Gastroesophageal Reflux Disease: an Improvement for Patient Management. Expert Rev Gastroenterol Hepatol. 2019;13(8):761-769. PubMed PMID: 31327288.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New classifications of gastroesophageal reflux disease: an improvement for patient management? AU - Ribolsi,Mentore, AU - Giordano,Antonio, AU - Guarino,Michele Pier Luca, AU - Tullio,Alessandro, AU - Cicala,Michele, Y1 - 2019/07/25/ PY - 2019/7/23/pubmed PY - 2019/7/23/medline PY - 2019/7/23/entrez KW - GERD KW - NERD KW - PPIs KW - lyon consensus KW - multichannel intraluminal impedance-pH SP - 761 EP - 769 JF - Expert review of gastroenterology & hepatology JO - Expert Rev Gastroenterol Hepatol VL - 13 IS - 8 N2 - Introduction: Gastroesophageal reflux disease (GERD) is a very common and often debilitating disease. In the broad spectrum of GERD phenotypes, three main groups may be traditionally distinguished: 1) patients only affected by esophageal and/or extra-esophageal symptoms; 2) patients with erosive esophagitis and 3) patients with further complications. Areas covered: This review provides an overview on the current classifications of GERD patients, and their impact on their management. Expert opinion: In 2017, the GERD Consensus Working Group focused the attention on patients unresponsive to PPIs. In this scenario, a diagnosis of GERD might be confirmed by evident signs of erosive esophagitis and the finding of pH or multichannel intraluminal impedance-pH tests, such as more than 6%. The 'Lyon Consensus' panel of experts confirmed that positive indices of reflux-symptom association, without other altered parameters, represent reflux hypersensitivity. GERD requires a customized management; it is crucial to assess frequency and severity of symptoms and their response to an optimal course of therapy as well as to explore the endoscopic alterations and consider other diagnoses responsible for persistent symptoms. SN - 1747-4132 UR - https://www.unboundmedicine.com/medline/citation/31327288/New_classifications_of_gastroesophageal_reflux_disease:_an_improvement_for_patient_management L2 - http://www.tandfonline.com/doi/full/10.1080/17474124.2019.1645596 DB - PRIME DP - Unbound Medicine ER -